Discovery of modulators of HIV-1 infection from the human peptidome (Q35222585)

7 August 2017

3 references

21 May 2022

22 August 2022

25 October 2022

Discovery of modulators of HIV-1 infection from the human peptidome (English)

1 reference

antimicrobial cationic peptides

7 August 2017

main subject

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human immunodeficiency virus infectious disease

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HIV type 1

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host-pathogen interaction

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immunologic factor

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peptide

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Frank Kirchhoff

1 reference

7 August 2017

Jan Münch

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7 August 2017

Ludger Ständker

series ordinal

1 reference

7 August 2017

Wolf-Georg Forssmann

series ordinal

1 reference

7 August 2017

language of work or name

English

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publication date

11 August 2014

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Nature Reviews Microbiology

7 August 2017

1 October 2014

3 references

21 May 2022

22 August 2022

25 October 2022

4 references

7 August 2017

21 May 2022

22 August 2022

25 October 2022

1 reference

7 August 2017

1 reference

7 August 2017

page(s)

715-722

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Initial sequencing and analysis of the human genome

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Modification-specific proteomics: characterization of post-translational modifications by mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

The blood peptidome: a higher dimension of information content for cancer biomarker discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Casocidin-I: a casein-alpha s2 derived peptide exhibits antibacterial activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

LEKTI, a novel 15-domain type of human serine proteinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Human hemoglobin-derived peptides exhibit antimicrobial activity: a class of host defense peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Antimicrobial activity of peptides derived from human ß-amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

C-terminal peptides of tissue factor pathway inhibitor are novel host defense molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Proteolytic activation transforms heparin cofactor II into a host defense molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Context mediates antimicrobial efficacy of kinocidin congener peptide RP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Antimicrobial peptides: general overview and clinical implications in human health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Defensins in viral infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

21 January 2018

Antimicrobial peptides

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Defensins. Natural peptide antibiotics of human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Histatins are the major wound-closure stimulating factors in human saliva as identified in a cell culture assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

On a Remarkable Bacteriolytic Element Found in Tissues and Secretions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Dermcidin: a novel human antibiotic peptide secreted by sweat glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Antimicrobial Peptides: Primeval Molecules or Future Drugs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Antimicrobial peptide elicitors: new hope for the post-antibiotic era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Antimicrobial peptides stage a comeback

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

The future of peptide-based drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Emerging themes and therapeutic prospects for anti-infective peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Peptide bank generated by large-scale preparation of circulating human peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Composition of the peptide fraction in human blood plasma: database of circulating human peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

HIV-1 inhibition by a peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Synthesized peptide inhibitors of HIV-1 gp41-dependent membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Identification of a major co-receptor for primary isolates of HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

The restriction factors of human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Hemofiltrate CC chemokine 1[9-74] causes effective internalization of CCR5 and is a potent inhibitor of R5-tropic human immunodeficiency virus type 1 strains in primary T cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Identification of the platelet-derived chemokine CXCL4/PF-4 as a broad-spectrum HIV-1 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Mutagenesis of a conserved fusion peptide-like motif and membrane-proximal heptad-repeat region of hepatitis C virus glycoprotein E1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Characterization of a highly conserved domain within the severe acute respiratory syndrome coronavirus spike protein S2 domain with characteristics of a viral fusion peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Prediction of arenavirus fusion peptides on the basis of computer analysis of envelope protein sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Structural properties of the putative fusion peptide of hepatitis B virus upon interaction with phospholipids. Circular dichroism and Fourier-transform infrared spectroscopy studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

The antibacterial chemokine MIG/CXCL9 is constitutively expressed in epithelial cells of the male urogenital tract and is present in seminal plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Antibacterial properties of the sperm-binding proteins and peptides of human epididymis 2 (HE2) family; salt sensitivity, structural dependence and their interaction with outer and cytoplasmic membranes of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Cationic polypeptides contribute to the anti-HIV-1 activity of human seminal plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Semen-derived amyloid fibrils drastically enhance HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Oligovalent amyloid-binding agents reduce SEVI-mediated enhancement of HIV-1 infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Amyloid-binding small molecules efficiently block SEVI (semen-derived enhancer of virus infection)- and semen-mediated enhancement of HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Seminal plasma and semen amyloids enhance cytomegalovirus infection in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Semen-derived enhancer of viral infection (SEVI) binds bacteria, enhances bacterial phagocytosis by macrophages, and can protect against vaginal infection by a sexually transmitted bacterial pathogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Preclinical predictors of anticancer drug efficacy: critical assessment with emphasis on whether nanomolar potency should be required of candidate agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

n-Nonanoyl-CC chemokine ligand 14, a potent CC chemokine ligand 14 analogue that prevents the recruitment of eosinophils in allergic airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Regulation of inflammation by extracellular acidification and proton-sensing GPCRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

hBD-1: a novel beta-defensin from human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

A peptide inhibitor of cytomegalovirus infection from human hemofiltrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Mass spectrometry-based proteomics: existing capabilities and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Antibacterial peptides for therapeutic use: obstacles and realistic outlook

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Development of resistance to VIR-353 with cross-resistance to the natural HIV-1 entry virus inhibitory peptide (VIRIP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

From antimicrobial to anticancer peptides. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Cathelicidin a potential therapeutic peptide for gastrointestinal inflammation and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Immune modulation by multifaceted cationic host defense (antimicrobial) peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Quantitative enzyme-linked immunosorbent assay determination of an abundant hemoglobin-derived anti-infective peptide in human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

21 January 2018

Therapeutic peptides.

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Antimicrobial activity of fibrinogen and fibrinogen-derived peptides – a novel link between coagulation and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Isolation of human cationic antimicrobial protein-18 from seminal plasma and its association with prostasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Liquid chromatography and electrospray mass spectrometric mapping of peptides from human plasma filtrate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Targeting the sticky fingers of HIV-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Constitutive expression of the antibacterial CXC chemokine GCP-2/CXCL6 by epithelial cells of the male reproductive tract

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3312

Systematic isolation of circulating human peptides: the concept of peptide trapping

31 March 2020

1 reference

12 December 2020

Cationic host defence peptides: multifaceted role in immune modulation and inflammation.

1 reference

12 December 2020

The influence of semen-derived enhancer of virus infection on the efficiency of retroviral gene transfer

1 reference

12 December 2020

Purification of novel peptide antibiotics from human milk

1 reference

12 December 2020

Hydrophobic binding of the ectodomain of influenza hemagglutinin to membranes occurs through the "fusion peptide"

1 reference

12 December 2020

Human natriuretic peptides exhibit antimicrobial activity.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRMICRO3312

1 reference

7 August 2017

0 references

1 reference