Identifying apicoplast-targeting antimalarials using high-throughput compatible approaches (Q35225061)

7 August 2017

title

Identifying apicoplast-targeting antimalarials using high-throughput compatible approaches (English)

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7 August 2017

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David A Fidock

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Eric H Ekland

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7 August 2017

Jessica Schneider

series ordinal

1 reference

7 August 2017

language of work or name

English

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publication date

11 July 2011

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7 August 2017

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

3583-3593

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Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites

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27 July 2018

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Spiroindolones, a potent compound class for the treatment of malaria

27 July 2018

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Malaria, Plasmodium falciparum and its apicoplast

27 July 2018

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Thousands of chemical starting points for antimalarial lead identification

27 July 2018

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Treatment with coartem (artemether-lumefantrine) in Papua New Guinea

27 July 2018

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Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria

27 July 2018

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ABC - antibiotics-based combinations for the treatment of severe malaria?

27 July 2018

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Artemisinin Resistance in Plasmodium falciparum Malaria

27 July 2018

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A var gene promoter implicated in severe malaria nucleates silencing and is regulated by 3' untranslated region and intronic cis-elements

27 July 2018

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Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

27 July 2018

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GFP-targeting allows visualization of the apicoplast throughout the life cycle of live malaria parasites

27 July 2018

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Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy

27 July 2018

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The evolution of drug-resistant malaria

27 July 2018

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Interactions of the malaria parasite and its mammalian host

27 July 2018

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

27 July 2018

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Apicoplast translation, transcription and genome replication: targets for antimalarial antibiotics

27 July 2018

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In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes

27 July 2018

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Malaria: progress, perils, and prospects for eradication

27 July 2018

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Telithromycin and quinupristin-dalfopristin induce delayed death in Plasmodium falciparum

27 July 2018

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A randomized controlled pilot trial of azithromycin or artesunate added to sulfadoxine-pyrimethamine as treatment for malaria in pregnant women

27 July 2018

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Antimalarial drug toxicity: a review

27 July 2018

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High-throughput Plasmodium falciparum growth assay for malaria drug discovery

27 July 2018

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In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin

27 July 2018

1 reference

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Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum

27 July 2018

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Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

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Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase

27 July 2018

1 reference

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Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast

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Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data

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Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.

27 July 2018

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Growth of Toxoplasma gondii is inhibited by aryloxyphenoxypropionate herbicides targeting acetyl-CoA carboxylase

27 July 2018

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Bacteraemia complicating severe malaria in children

27 July 2018

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Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

27 July 2018

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Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum

27 July 2018

1 reference

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Use of hydroethidine and flow cytometry to assess the effects of leukocytes on the malarial parasite Plasmodium falciparum

27 July 2018

1 reference

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Drug resistance in Plasmodium berghei Vincke and Lips, 1948. I. Chloroquine resistance

27 July 2018

1 reference

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Doxycycline for malaria chemoprophylaxis and treatment: report from the CDC expert meeting on malaria chemoprophylaxis

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Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites

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1 reference

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1 reference

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1 reference

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Chemical genetics of Plasmodium falciparum

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1 reference

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1 reference

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Apicoplast and mitochondrion in gametocytogenesis of Plasmodium falciparum.

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177575

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26 September 2018

1 reference

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Re-evaluating acridine orange for rapid flow cytometric enumeration of parasitemia in malaria-infected rodents.

26 September 2018

1 reference

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The effects of anti-bacterials on the malaria parasite Plasmodium falciparum.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177575

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1 reference

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Improvement of detection specificity of Plasmodium-infected murine erythrocytes by flow cytometry using autofluorescence and YOYO-1.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177575

Protein farnesyltransferase inhibitors exhibit potent antimalarial activity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177575

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26 September 2018

1 reference

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1 reference

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26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177575

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21746861

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

KITASAMYCIN. EXPERIMENTAL "IN VITRO" STUDY AND 1ST CLINICAL RESULTS

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21746861

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1096/FJ.11-187401

1 reference

7 August 2017

1 reference

7 August 2017

1 reference