Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53. (Q35208579)

7 August 2017

title

Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53. (English)

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7 August 2017

simian virus 40

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1 reference

S A McCarthy

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7 August 2017

H S Symonds

series ordinal

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7 August 2017

T Van Dyke

series ordinal

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7 August 2017

language of work or name

English

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publication date

1 April 1994

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Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

3979-3983

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p53 is required for radiation-induced apoptosis in mouse thymocytes

7 August 2017

cites work

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Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant

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13 July 2018

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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

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Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic mice

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13 July 2018

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13 July 2018

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

13 July 2018

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Mls--a retrovirus exploits the immune system

13 July 2018

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13 July 2018

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Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication

13 July 2018

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13 July 2018

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13 July 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

13 July 2018

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13 July 2018

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Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

13 July 2018

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The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein

13 July 2018

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Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

13 July 2018

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p53: the ultimate tumor suppressor gene?

13 July 2018

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Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription

13 July 2018

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

13 July 2018

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T-antigen mutant activities in vivo: roles of p53 and pRB binding in tumorigenesis of the choroid plexus

13 July 2018

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

13 July 2018

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Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death

26 September 2018

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Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

26 September 2018

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12 December 2020

Wild-type p53 activates transcription in vitro

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12 December 2020

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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12 December 2020

The effects of immunosuppressive drugs on the regulation of activation-induced apoptotic cell death in thymocytes

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12 December 2020

Identifiers

DOI

10.1073/PNAS.91.9.3979

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7 August 2017

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7 August 2017

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