Affective disorders, antidepressant drugs and brain metabolism (Q35204087)

7 August 2017

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title

Affective disorders, antidepressant drugs and brain metabolism (English)

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7 August 2017

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Moretti A

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7 August 2017

Gorini A

series ordinal

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7 August 2017

Villa RF

series ordinal

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7 August 2017

language of work or name

English

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publication date

1 September 2003

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7 August 2017

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

773-785

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Initiation and adaptation: a paradigm for understanding psychotropic drug action

7 August 2017

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21 January 2018

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G proteins: implications for psychiatry

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Second messenger-regulated protein kinases in the brain: their functional role and the action of antidepressant drugs

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Abnormalities of cAMP signaling in affective disorders: implication for pathophysiology and treatment

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Signal transduction pathways. Molecular targets for lithium's actions

21 January 2018

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G proteins in signal transduction

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The Albert Lasker Medical Awards. G proteins and regulation of adenylyl cyclase

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Homologous and heterologous regulation of receptor-stimulated phosphoinositide hydrolysis

21 January 2018

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Anti-bipolar therapy: mechanism of action of lithium

21 January 2018

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Neuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function

21 January 2018

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Cyclic nucleotide-dependent protein kinases

21 January 2018

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Transcriptional regulation by cyclic AMP

21 January 2018

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The protein kinase C family for neuronal signaling

21 January 2018

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Localization of protein kinases by anchoring proteins: a theme in signal transduction

21 January 2018

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Cerebral cortex Gs alpha protein levels and forskolin-stimulated cyclic AMP formation are increased in bipolar affective disorder

21 January 2018

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G Protein-coupled cyclic AMP signaling in postmortem brain of subjects with mood disorders: effects of diagnosis, suicide, and treatment at the time of death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Increased cyclic AMP-dependent protein kinase activity in postmortem brain from patients with bipolar affective disorder

21 January 2018

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Increased association of brain protein kinase C with the receptor for activated C kinase-1 (RACK1) in bipolar affective disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Abnormal G protein alpha(s) - and alpha(i2)-subunit mRNA expression in bipolar affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Abnormalities of cAMP-dependent endogenous phosphorylation in platelets from patients with bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Abnormalities in protein kinase C signaling and the pathophysiology of bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Lithium regulates PKC-mediated intracellular cross-talk and gene expression in the CNS in vivo

21 January 2018

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Melatonin release from pineal cells of diurnal and nocturnal birds

21 January 2018

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Brain [3H]cAMP binding sites are unaltered in depressed suicides, but decreased by antidepressants

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Increased temporal cortex CREB concentrations and antidepressant treatment in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

cAMP-dependent phosphorylation system after short and long-term administration of moclobemide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Selective adenylate cyclase increase in the limbic area of long-term imipramine-treated rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Effects of imipramine and sertraline on protein kinase activity in rat frontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Effects of fluvoxamine on the protein phosphorylation system associated with rat neuronal microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Serine/threonine kinases as molecular targets of antidepressants: implications for pharmacological treatment and pathophysiology of affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

The effect of prolonged imipramine and electroconvulsive shock treatment on calcium/calmodulin-dependent protein kinase II in the hippocampus of rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Modifications in brain CaM kinase II after long-term treatment with desmethylimipramine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Neural plasticity to stress and antidepressant treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Neurogenesis in the adult human hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Cortical grey matter reductions associated with treatment-resistant chronic unipolar depression. Controlled magnetic resonance imaging study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Hippocampal volume reduction in major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

The anatomy of mood disorders--review of structural neuroimaging studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Neuroplasticity and cellular resilience in mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Regulation of adult neurogenesis by antidepressant treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Antidepressant-like effect of brain-derived neurotrophic factor (BDNF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Effects of chronic lithium treatment on protein kinase C and cyclic AMP-dependent protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Altered protein phosphorylation in the rat brain following chronic lithium and carbamazepine treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Lithium treatment inhibits protein kinase C translocation in rat brain cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Modulation of protein kinase C isozymes and substrates by lithium: the role of myo-inositol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Positron emission tomography provides molecular imaging of biological processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Neuroimaging in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Neuroimaging studies of mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Neuroimaging in bipolar disorder: what have we learned?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

PET measurements of brain glucose metabolism and blood flow in major depressive disorder: a critical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Functional neuroimaging studies of depression: the anatomy of melancholia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Subgenual prefrontal cortex abnormalities in mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Prefrontal cortical-amygdalar metabolism in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy: preliminary findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Effect of sertraline on regional metabolic rate in patients with affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Cingulate function in depression: a potential predictor of treatment response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Effect of sleep deprivation on brain metabolism of depressed patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Brain metabolic changes associated with symptom factor improvement in major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

The tricyclic antidepressant clomipramine dose-dependently reduces regional cerebral metabolic rates for glucose in awake rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Uptake of 99mTc-exametazime shown by single photon emission computed tomography before and after lithium withdrawal in bipolar patients: associations with mania

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Magnetic resonance spectroscopy in affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Multinuclear magnetic resonance spectroscopy studies of brain purines in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Reduction of brain phosphocreatine in bipolar II disorder detected by phosphorus-31 magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Brain phosphorous metabolism in depressive disorders detected by phosphorus-31 magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Alterations in brain phosphorous metabolism in bipolar disorder detected by in vivo 31P and 7Li magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Decreased brain intracellular pH measured by 31P-MRS in bipolar disorder: a confirmation in drug-free patients and correlation with white matter hyperintensity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

31P magnetic resonance spectroscopy in the frontal lobe of major depressed patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Lower levels of nucleoside triphosphate in the basal ganglia of depressed subjects: a phosphorous-31 magnetic resonance spectroscopy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Effect of photic stimulation on human visual cortex lactate and phosphates using 1H and 31P magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

The Na,K-ATPase hypothesis for bipolar illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

N-acetylaspartate in neuropsychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Decreased dorsolateral prefrontal N-acetyl aspartate in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

The relationship between dorsolateral prefrontal N-acetylaspartate measures and striatal dopamine activity in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Magnetic resonance assessment of cerebral perfusion in depressed cardiac patients: preliminary findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Cerebrovascular disease and depression symptoms in the cardiovascular health study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Na+,K(+)-ATPase activity in CNS and noradrenergic neurotransmission: time course of differential desipramine (DMI) effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Mitochondrial DNA polymorphisms in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Mitochondrial dysfunction in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

ATPases of synaptic plasma membranes from hippocampus after ischemia and recovery during ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Effect of hypoxia on protein composition of synaptic plasma membranes from cerebral cortex during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Mitochondrial factors involved in Parkinson's disease by MPTP toxicity in Macaca fascicularis and drug effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

ATPases enzyme activities during ageing in different types of somatic and synaptic plasma membranes from rat frontal cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Cerebral Metabolic Responses to Clomipramine Are Greatly Reduced Following Pretreatment with the Specific Serotonin Neurotoxin Para-Chloroamphetamine (PCA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

Agonist-induced, GTP-dependent phosphoinositide hydrolysis in postmortem human brain membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Receptor-mediated activation of G proteins is increased in postmortem brains of bipolar affective disorder subjects.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Reduced adenylyl cyclase immunolabeling and activity in postmortem temporal cortex of depressed suicide victims

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Reduced [3H]cyclic AMP binding in postmortem brain from subjects with bipolar affective disorder.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

The phosphoinositide signal transduction system is impaired in bipolar affective disorder brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Elevated platelet membrane phosphatidylinositol-4,5-bisphosphate in bipolar mania

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Altered Rap1 endogenous phosphorylation and levels in platelets from patients with bipolar disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Mononuclear leukocyte levels of G proteins in depressed patients with bipolar disorder or major depressive disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

High levels of Gs alpha in platelets of euthymic patients with bipolar affective disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Imbalance of the Gs and Gi/o function in post-mortem human brain of depressed patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

[(3)H]cAMP binding sites and protein kinase a activity in the prefrontal cortex of suicide victims

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Alterations in phosphoinositide signaling and G-protein levels in depressed suicide brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

cAMP-dependent protein kinase activity in major depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Cyclic AMP-dependent protein kinase in subtypes of major depression and normal volunteers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Protein kinase A and Rap1 levels in platelets of untreated patients with major depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Effects of tricyclic antidepressants on protein kinase C activity in rabbit and human platelets in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Time-course changes in rat cerebral cortex subcellular distribution of the cyclic-AMP binding after treatment with selective serotonin reuptake inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Chronic antidepressant administration alters the subcellular distribution of cyclic AMP-dependent protein kinase in rat frontal cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Long-term blockade of serotonin reuptake affects synaptotagmin phosphorylation in the hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Effects of chronic lithium treatment on agonist-enhanced extracellular concentrations of cyclic AMP in the dorsal hippocampus of freely moving rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Inhibitory effect of lithium on cAMP dependent phosphorylation system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Changes in regional cerebral blood flow on recovery from depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Brain metabolic changes in major depressive disorder from pre- to post-treatment with paroxetine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

State changes in brain activity shown by the uptake of 99mTc-exametazime with single photon emission tomography in major depression before and after treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Lateralized abnormality of high energy phosphate metabolism in the frontal lobes of patients with bipolar disorder detected by phase-encoded 31P-MRS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Abnormal frontal lobe phosphorous metabolism in bipolar disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Altered brain energy metabolism in lithium-resistant bipolar disorder detected by photic stimulated 31P-MR spectroscopy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Stimulation of Na+,K+-ATPase activity in certain membranes of the rat central nervous system (CNS) by acute administration of desipramine (DMI)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Influence of dose and route of administration on the kinetics of fluoxetine and its metabolite norfluoxetine in the rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Increased levels of a mitochondrial DNA deletion in the brain of patients with bipolar disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

A critique on the preparation and enzymatic characterization of synaptic and nonsynaptic mitochondria from hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001353

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001353

1 reference

7 August 2017

1 reference