Calpeptin attenuated inflammation, cell death, and axonal damage in animal model of multiple sclerosis (Q35189764)

7 August 2017

title

Calpeptin attenuated inflammation, cell death, and axonal damage in animal model of multiple sclerosis (English)

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7 August 2017

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M Kelly Guyton

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7 August 2017

Arabinda Das

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7 August 2017

Supriti Samantaray

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7 August 2017

Gerald C Wallace

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7 August 2017

Jonathan T Butler

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7 August 2017

Swapan K Ray

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7 August 2017

Naren L Banik

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7 August 2017

language of work or name

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1 August 2010

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Journal of Neuroscience Research

7 August 2017

published in

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

2398-2408

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The human host defense peptide LL-37 induces apoptosis in a calpain- and apoptosis-inducing factor-dependent manner involving Bax activity.

7 August 2017

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Pathophysiological role of calpain in experimental demyelination

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28 July 2018

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28 July 2018

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Changes in cathepsins B-1 and D, neutral proteinase and 2',3'-cyclic nucleotide-3'-phosphohydrolase activities in monkey brain with experimental allergic encephalomyelitis

28 July 2018

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28 July 2018

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Calpain inhibitor inhibits p35-p25-Cdk5 activation, decreases tau hyperphosphorylation, and improves neurological function after spinal cord hemisection in rats

28 July 2018

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Crossref

https://api.crossref.org/works/10.1002%2FJNR.22408

Inhibition of calpain attenuates encephalitogenicity of MBP-specific T cells

21 January 2018

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Distribution of parvalbumin and calretinin immunoreactive interneurons in motor cortex from multiple sclerosis post-mortem tissue

27 September 2018

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Protein co-expression with axonal injury in multiple sclerosis plaques.

27 September 2018

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Inhibition of calpain and caspase-3 prevented apoptosis and preserved electrophysiological properties of voltage-gated and ligand-gated ion channels in rat primary cortical neurons exposed to glutamate

27 September 2018

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Aminoguanidine inhibits caspase-3 and calpain activation without affecting microglial activation following neonatal transient cerebral ischemia

27 September 2018

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Proliferation and death of oligodendrocytes and myelin proteins are differentially regulated in male and female rodents.

27 September 2018

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Calpain activation in apoptosis of ventral spinal cord 4.1 (VSC4.1) motoneurons exposed to glutamate: calpain inhibition provides functional neuroprotection

27 September 2018

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Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors.

27 September 2018

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Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax.

27 September 2018

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Calpain expression and infiltration of activated T cells in experimental allergic encephalomyelitis over time: increased calpain activity begins with onset of disease

27 September 2018

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Inhibition of calpain-mediated apoptosis by E-64 d-reduced immediate early gene (IEG) expression and reactive astrogliosis in the lesion and penumbra following spinal cord injury in rats

27 September 2018

1 reference

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Combined TUNEL and double immunofluorescent labeling for detection of apoptotic mononuclear phagocytes in autoimmune demyelinating disease

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164817

Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164817

Calpastatin is up-regulated in response to hypoxia and is a suicide substrate to calpain after neonatal cerebral hypoxia-ischemia

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164817

Balancing function vs. self defense: the CNS as an active regulator of immune responses

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164817

Upregulation of calpain activity and expression in experimental allergic encephalomyelitis: a putative role for calpain in demyelination

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164817

A new mechanism of methylprednisolone and other corticosteroids action demonstrated in vitro: inhibition of a proteinase (calpain) prevents myelin and cytoskeletal protein degradation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164817

Peptide bond specificity of calpain: proteolysis of human myelin basic protein

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164817

Calpeptin and methylprednisolone inhibit apoptosis in rat spinal cord injury

27 September 2018

1 reference

12 December 2020

Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients

1 reference

12 December 2020

The effects of calpain inhibition upon IL-2 and CD25 expression in human peripheral blood mononuclear cells

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12 December 2020

Prevalence estimates for MS in the United States and evidence of an increasing trend for women

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12 December 2020

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12 December 2020

Synthesis of a new cell penetrating calpain inhibitor (calpeptin)

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12 December 2020

Bax cleavage is mediated by calpain during drug-induced apoptosis

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12 December 2020

Calpain activity and expression are increased in splenic inflammatory cells associated with experimental allergic encephalomyelitis

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12 December 2020

LFA-1 to LFA-1 signals involve zeta-associated protein-70 (ZAP-70) tyrosine kinase: relevance for invasion and migration of a T cell hybridoma

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12 December 2020

Upregulation of calpain correlates with increased neurodegeneration in acute experimental auto-immune encephalomyelitis

1 reference

12 December 2020

A novel calpain inhibitor for the treatment of acute experimental autoimmune encephalomyelitis

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12 December 2020

Identifiers

DOI

10.1002/JNR.22408

1 reference

7 August 2017

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7 August 2017

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