The echinocandin antifungals: an overview of the pharmacology, spectrum and clinical efficacy (Q35185757)

7 August 2017

1 reference

title

The echinocandin antifungals: an overview of the pharmacology, spectrum and clinical efficacy (English)

1 reference

7 August 2017

1 reference

Nathan Paul Wiederhold

1 reference

ORCID Public Data File 2021

author name string

Nathan P Wiederhold

series ordinal

1 reference

7 August 2017

Russell E Lewis

series ordinal

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 August 2003

1 reference

Expert Opinion on Investigational Drugs

7 August 2017

published in

1 reference

7 August 2017

1 reference

7 August 2017

1 reference

7 August 2017

page(s)

1313-1333

1 reference

Antibiotics that inhibit fungal cell wall development

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Efficacy of cilofungin alone and in combination with amphotericin B in a murine model of disseminated aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Clinical efficacy of echinocandin antifungals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Antifungal activities of fluconazole, caspofungin (MK0991), and anidulafungin (LY 303366) alone and in combination against Candida spp. and Crytococcus neoformans via time-kill methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Killing activity of micafungin against Aspergillus fumigatus hyphae assessed by specific fluorescent staining for cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Antifungal activity of the echinocandin anidulafungin (VER002, LY-303366) against yeast pathogens: a comparative study with M27-A microdilution method

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

In vitro activity of two echinocandin derivatives, LY303366 and MK-0991 (L-743,792), against clinical isolates of Aspergillus, Fusarium, Rhizopus, and other filamentous fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

In vitro antifungal activity of Micafungin (FK463) against dimorphic fungi: comparison of yeast-like and mycelial forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

In vitro activity of FK463, a novel lipopeptide antifungal agent, against a variety of clinically important molds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

In vitro activity of three new triazoles and one echinocandin against Candida bloodstream isolates from cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Overexpression of Sbe2p, a Golgi protein, results in resistance to caspofungin in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of disseminated candidiasis and aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Antifungal susceptibility testing: practical aspects and current challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Comparative evaluation of disk diffusion with microdilution assay in susceptibility testing of caspofungin against Aspergillus and Fusarium isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Evaluation of Etest method for determining caspofungin (MK-0991) susceptibilities of 726 clinical isolates of Candida species

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Dosage-dependent antifungal efficacy of V-echinocandin (LY303366) against experimental fluconazole-resistant oropharyngeal and esophageal candidiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

In vivo pharmacodynamics of HMR 3270, a glucan synthase inhibitor, in a murine candidiasis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Cilofungin (LY121019), an antifungal agent with specific activity against Candida albicans and Candida tropicalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

In vitro pharmacodynamic properties of three antifungal agents against preformed Candida albicans biofilms determined by time-kill studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Riddle of biofilm resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Emergence of Candida parapsilosis as the predominant species causing candidemia in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Single- and multiple-dose pharmacokinetics of caspofungin in healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Refractory Aspergillus pneumonia in patients with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Randomized, double-blind, multicenter study of caspofungin versus amphotericin B for treatment of oropharyngeal and esophageal candidiases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Efficacy of caspofungin in the treatment of esophageal candidiasis resistant to fluconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Safety and tolerability of caspofungin acetate in the treatment of fungal infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Efficacies of two new antifungal agents, the triazole ravuconazole and the echinocandin LY-303366, in an experimental model of invasive aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Pharmacokinetic and pharmacodynamic modeling of anidulafungin (LY303366): reappraisal of its efficacy in neutropenic animal models of opportunistic mycoses using optimal plasma sampling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Comparison of the echinocandin caspofungin with amphotericin B for treatment of histoplasmosis following pulmonary challenge in a murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Correlation between antifungal susceptibilities of Coccidioides immitis in vitro and antifungal treatment with caspofungin in a mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Efficacies of fluconazole, caspofungin, and amphotericin B in Candida glabrata-infected p47phox-/- knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of pulmonary aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Efficacy of FK463, a (1,3)-beta-D-glucan synthase inhibitor, in disseminated azole-resistant candida albicans infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Prophylactic effect of FK463, a novel antifungal lipopeptide, against Pneumocystis carinii infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

Activity of micafungin (FK463) against an itraconazole-resistant strain of Aspergillus fumigatus and a strain of Aspergillus terreus demonstrating in vivo resistance to amphotericin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.8.1313

10.1517/13543784.12.8.1313

21 January 2018

Identifiers

DOI

1 reference

7 August 2017

1 reference