Protease Inhibitor–Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus (Q35164008)

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scientific article published on November 4, 2010

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English	Protease Inhibitor–Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus	scientific article published on November 4, 2010

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instance of

scholarly article

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Europe PubMed Central

PubMed publication ID

21056040

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6 August 2017

title

Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus (English)

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stated in

Europe PubMed Central

PubMed publication ID

21056040

retrieved

6 August 2017

Protease Inhibitor–Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus (English)

1 reference

stated in

Crossref

DOI

10.1053/J.GASTRO.2010.10.056

reference URL

https://api.crossref.org/works/10.1053/J.GASTRO.2010.10.056

retrieved

21 August 2024

main subject

Hepatitis C virus

1 reference

based on heuristic

inferred from title

virus

1 reference

based on heuristic

inferred from title

hepatitis C

1 reference

based on heuristic

inferred from title

fitness

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21056040

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

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21 August 2024

author

Stefan Zeuzem

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6

object named as

Stefan Zeuzem

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Europe PubMed Central

PubMed publication ID

21056040

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6 August 2017

Christoph Welsch

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2

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Christoph Welsch

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Europe PubMed Central

PubMed publication ID

21056040

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

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21 August 2024

David R. McGivern

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4

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David R. McGivern

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Europe PubMed Central

PubMed publication ID

21056040

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

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21 August 2024

author name string

Tetsuro Shimakami

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1

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Europe PubMed Central

PubMed publication ID

21056040

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6 August 2017

Daisuke Yamane

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3

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Europe PubMed Central

PubMed publication ID

21056040

retrieved

6 August 2017

Minkyung Yi

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5

1 reference

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Europe PubMed Central

PubMed publication ID

21056040

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6 August 2017

Stanley M. Lemon

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7

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Europe PubMed Central

PubMed publication ID

21056040

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

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language of work or name

English

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publication date

4 November 2010

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Europe PubMed Central

PubMed publication ID

21056040

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6 August 2017

full work available at URL

http://www.gastrojournal.org/article/S0016508510015969/pdf

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Portable Document Format

online access status

open access

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Europe PubMed Central

PubMed publication ID

21056040

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

retrieved

21 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21056040/pdf/?tool=EBI

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Portable Document Format

online access status

open access

content deliverer

PubMed Central

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Europe PubMed Central

PubMed publication ID

21056040

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

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21 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21056040/?tool=EBI

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HTML

online access status

open access

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PubMed Central

1 reference

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Europe PubMed Central

PubMed publication ID

21056040

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

retrieved

21 August 2024

https://europepmc.org/articles/PMC3155954

file format

HTML

online access status

open access

content deliverer

Europe PubMed Central

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21056040

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

retrieved

21 August 2024

https://europepmc.org/articles/PMC3155954?pdf=render

file format

Portable Document Format

online access status

open access

content deliverer

Europe PubMed Central

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21056040

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

retrieved

21 August 2024

https://doi.org/10.1053/j.gastro.2010.10.056

online access status

open access

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21056040

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21056040

retrieved

21 August 2024

https://api.elsevier.com/content/article/PII:S0016508510015969?httpAccept=text/xml

1 reference

stated in

Crossref

DOI

10.1053/J.GASTRO.2010.10.056

reference URL

https://api.crossref.org/works/10.1053/J.GASTRO.2010.10.056

retrieved

21 August 2024

https://api.elsevier.com/content/article/PII:S0016508510015969?httpAccept=text/plain

1 reference

stated in

Crossref

DOI

10.1053/J.GASTRO.2010.10.056

reference URL

https://api.crossref.org/works/10.1053/J.GASTRO.2010.10.056

retrieved

21 August 2024

published in

Gastroenterology

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stated in

Europe PubMed Central

PubMed publication ID

21056040

retrieved

6 August 2017

volume

140

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stated in

Europe PubMed Central

PubMed publication ID

21056040

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6 August 2017

issue

2

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Europe PubMed Central

PubMed publication ID

21056040

retrieved

6 August 2017

page(s)

667-675

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Europe PubMed Central

PubMed publication ID

21056040

retrieved

6 August 2017

cites work

Induction and evasion of innate antiviral responses by hepatitis C virus

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155954

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13 July 2018

MK-7009, a Potent and Selective Inhibitor of Hepatitis C Virus NS3/4A Protease

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13 July 2018

Hepatitis C: recent successes and continuing challenges in the development of improved treatment modalities

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Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection

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13 July 2018

Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients

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13 July 2018

Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)

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13 July 2018

NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly

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13 July 2018

Relative Replication Capacity and Selective Advantage Profiles of Protease Inhibitor-Resistant Hepatitis C Virus (HCV) NS3 Protease Mutants in the HCV Genotype 1b Replicon System

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13 July 2018

Phenotypic Characterization of Resistant Val36 Variants of Hepatitis C Virus NS3-4A Serine Protease

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13 July 2018

Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha

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13 July 2018

Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells

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Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034.

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13 July 2018

Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations

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Adaptive mutations producing efficient replication of genotype 1a hepatitis C virus RNA in normal Huh7 cells

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Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

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A novel recombinant single-chain hepatitis C virus ns3-ns4a protein with improved helicase activity

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Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

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Rapid HCV-RNA decline with once daily TMC435: a phase I study in healthy volunteers and hepatitis C patients

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Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients

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27 September 2018

Telaprevir and peginterferon with or without ribavirin for chronic HCV infection

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PubMed Central

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27 September 2018

Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment-naive subjects

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Characterization of resistance mutations against HCV ketoamide protease inhibitors

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Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir

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SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders

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RNA virus fitness.

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27 September 2018

Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins

series ordinal

26

1 reference

stated in

Crossref

DOI

10.1053/J.GASTRO.2010.10.056

reference URL

https://api.crossref.org/works/10.1053/J.GASTRO.2010.10.056

retrieved

21 August 2024

Identifiers

DOI

10.1053/J.GASTRO.2010.10.056

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21056040

retrieved

6 August 2017

PMC publication ID

3155954

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21056040

retrieved

6 August 2017

PubMed publication ID

21056040

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21056040

retrieved

6 August 2017

ResearchGate publication ID

47699984

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