Angiopoietins in angiogenesis and beyond (Q35143988)

6 August 2017

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title

Angiopoietins in angiogenesis and beyond (English)

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6 August 2017

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Stelios Tsigkos

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6 August 2017

Micheal Koutsilieris

series ordinal

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6 August 2017

Andreas Papapetropoulos

series ordinal

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6 August 2017

language of work or name

English

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publication date

1 June 2003

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Expert Opinion on Investigational Drugs

6 August 2017

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

933-941

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Mechanisms of angiogenesis

6 August 2017

cites work

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https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Mechanisms of angiogenesis and arteriogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-1, unlike angiopoietin-2, is incorporated into the extracellular matrix via its linker peptide region

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Evidence for heterotypic interaction between the receptor tyrosine kinases TIE-1 and TIE-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Vascular endothelial growth factor modulates the Tie-2:Tie-1 receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Tie2 Expression and Phosphorylation in Angiogenic and Quiescent Adult Tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Expression of angiopoietin-1 and its receptor TEK in hematopoietic cells from patients with myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Tie2 receptor expression is stimulated by hypoxia and proinflammatory cytokines in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietins 3 and 4: diverging gene counterparts in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Orchestration of angiogenesis and arteriovenous contribution by angiopoietins and vascular endothelial growth factor (VEGF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Expression of angiopoietin-2 by human endometrial endothelial cells: regulation by hypoxia and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Leptin induces angiopoietin-2 expression in adipose tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Abnormal uterine bleeding during progestin-only contraception may result from free radical-induced alterations in angiopoietin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Regulation of angiopoietin and Tie-2 receptor expression in non-reproductive tissues by estrogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-1 protects the adult vasculature against plasma leakage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-1 induces sprouting angiogenesis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-1 is an apoptosis survival factor for endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Mechanisms which mediate the antiapoptotic effects of angiopoietin-1 on endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-1 and its receptor Tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Tie receptors: new modulators of angiogenic and lymphangiogenic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Endothelial receptor tyrosine kinases activate the STAT signaling pathway: mutant Tie-2 causing venous malformations signals a distinct STAT activation response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

What Is the Evidence That Tumors Are Angiogenesis Dependent?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Expression and function of angiopoietin-1 in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Expression of Tie1, Tie2, and angiopoietins 1, 2, and 4 in Kaposi's sarcoma and cutaneous angiosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Increased Tie2 expression, enhanced response to angiopoietin-1, and dysregulated angiopoietin-2 expression in hemangioma-derived endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-1, angiopoietin-2 and Tie-2 in tumour and non-tumour tissues during growth of experimental melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiogenesis in acute myeloid leukemia and myelodysplastic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

HER2 regulatory control of angiopoietin-2 in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

In situ expression of angiopoietins in astrocytomas identifies angiopoietin-2 as an early marker of tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Gene therapy for gastric ulcers with single local injection of naked DNA encoding VEGF and angiopoietin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Suppression of diabetic retinopathy with angiopoietin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Signaling molecules in nonfamilial pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Protective role of angiopoietin-1 in experimental pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

Angiopoietin-1 Protects Against the Development of Cardiac Allograft Arteriosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.6.933

10.1517/13543784.12.6.933

21 January 2018

Identifiers

DOI

1 reference

6 August 2017

1 reference