Peripheral tachykinin receptors as potential therapeutic targets in visceral diseases (Q35143893)

6 August 2017

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title

Peripheral tachykinin receptors as potential therapeutic targets in visceral diseases (English)

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6 August 2017

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Alessandro Lecci

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6 August 2017

Carlo Alberto Maggi

series ordinal

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6 August 2017

language of work or name

English

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publication date

1 June 2003

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Expert Opinion on Therapeutic Targets

6 August 2017

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

343-362

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Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons.

6 August 2017

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Regulation of neuropeptide expression in sympathetic neurons. Paracrine and retrograde influences

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The effects of tachykinins on inflammatory and immune cells

21 January 2018

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Airway inflammation and tachykinins: prospects for the development of tachykinin receptor antagonists

21 January 2018

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Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis

21 January 2018

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A regulatory role for neurokinin B in placental physiology and pre-eclampsia

21 January 2018

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Substance P induced preprotachykinin-a mRNA, neutral endopeptidase mRNA and substance P in cultured normal fibroblasts

21 January 2018

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Airway smooth muscle cells express functional neurokinin-1 receptors and the nerve-derived preprotachykinin-a gene: regulation by passive sensitization

21 January 2018

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Identification of a tachykinin NK(2) receptor splice variant and its expression in human and rat tissues

21 January 2018

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Pharmacological profile of the novel mammalian tachykinin, hemokinin 1

21 January 2018

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Discovery of the antidepressant and anti-emetic efficacy of substance P receptor (NK1) antagonists

21 January 2018

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Correlation of neurokinin (NK) 1 receptor occupancy in gerbil striatum with behavioral effects of NK1 antagonists

21 January 2018

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Respiratory actions of tachykinins in the nucleus of the solitary tract: characterization of receptors using selective agonists and antagonists

21 January 2018

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Role of nitric oxide and septide-insensitive NK(1) receptors in bronchoconstriction induced by aerosolised neurokinin A in guinea-pigs

21 January 2018

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NK1 receptor stimulation causes contraction and inositol phosphate increase in medium-size human isolated bronchi

21 January 2018

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Particulate matter initiates inflammatory cytokine release by activation of capsaicin and acid receptors in a human bronchial epithelial cell line

21 January 2018

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Differential role of neurokinin receptors in human lymphocyte and monocyte chemotaxis

21 January 2018

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NK1 receptor antagonist CP-99,994 inhibits cigarette smoke-induced neutrophil and eosinophil adhesion in rat tracheal venules

21 January 2018

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Alleviation of wood smoke-induced lung injury by tachykinin receptor antagonist and hydroxyl radical scavenger in guinea pigs

21 January 2018

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Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation.

21 January 2018

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Involvement of tachykinin NK1 and NK2 receptors in substance P-induced microvascular leakage hypersensitivity and airway hyperresponsiveness in guinea-pigs

21 January 2018

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Acetylcholine and tachykinin receptor antagonists attenuate wood smoke-induced bronchoconstriction in guinea pigs

21 January 2018

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Effects of tachykinin NK1 receptor antagonists on vagal hyperreactivity and neuronal M2 muscarinic receptor function in antigen challenged guinea-pigs

21 January 2018

1 reference

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Neurokinin-1 receptor antagonist inhibits short-term sulfuric-acid-induced airway hyperresponsiveness in sensitized guinea pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Role of tachykinins in sephadex-induced airway hyperreactivity and inflammation in guinea pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Interactions between inflammatory cells and nerves

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Tachykinin NK(2) receptors facilitate acetylcholine release from guinea-pig isolated trachea

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Nitric oxide is generated in smooth muscle layer by neurokinin A and counteracts constriction in guinea pig airway

21 January 2018

1 reference

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Characterization of the antibronchoconstrictor activity of MEN 11420, a tachykinin NK2 receptor antagonist, in guinea-pigs.

21 January 2018

1 reference

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NK(2)-receptor mediated contraction in monkey, guinea-pig and human airway smooth muscle

21 January 2018

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Effect of tachykinins on airway function in cynomolgus monkeys

21 January 2018

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Role of tachykinin NK2-receptor activation in the allergen-induced late asthmatic reaction, airway hyperreactivity and airway inflammatory cell influx in conscious, unrestrained guinea-pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

The involvement of sensory neuropeptides in airway hyper-responsiveness in rabbits sensitized and challenged to Parietaria judaica

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Tachykinins via Tachykinin NK(2) receptor activation mediate ozone-induced increase in the permeability of the tracheal mucosa in guinea-pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Effect of inhaled fluticasone on bronchial responsiveness to neurokinin A in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

The NK-2 receptor antagonist SR 48968C does not improve adenosine hyperresponsiveness and airway obstruction in allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Protection against bradykinin-induced bronchoconstriction in asthmatic patients by neurokinin receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Effect of the two tachykinin antagonists, SR 48968 and SR 140333, on cough induced by citric acid in the unanaesthetized guinea pig

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Neurokinin B- and specific tachykinin NK(3) receptor agonists-induced airway hyperresponsiveness in the guinea-pig

21 January 2018

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Biochemical and pharmacological activities of SSR 146977, a new potent nonpeptide tachykinin NK3 receptor antagonist

21 January 2018

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SR 142801, a tachykinin NK(3) receptor antagonist, prevents beta(2)-adrenoceptor agonist-induced hyperresponsiveness to neurokinin A in guinea-pig isolated trachea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Tachykinin NK(3) receptor agonists induced microvascular leakage hypersensitivity in the guinea-pig airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Tachykinin NK3 and NK1 receptor activation elicits secretion from porcine airway submucosal glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

A tachykinin NK3 receptor antagonist, SR 142801 (osanetant), prevents substance P-induced bronchial hyperreactivity in guinea-pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Effects of specific tachykinin receptor antagonists on citric acid-induced cough and bronchoconstriction in unanesthetized guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Tachykinin Receptor Antagonists and Cough

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Central antitussive activity of the NK1 and NK2 tachykinin receptor antagonists, CP-99,994 and SR 48968, in the guinea-pig and cat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Role of NK2 receptors in gastric barosensitivity and in experimental ileus in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Irritable bowel syndrome: new agents targeting serotonin receptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Effects of tachykinin NK1 receptor antagonists on the viscerosensory response caused by colorectal distention in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Sensitization of enteric reflexes in the rat colon in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Role of tachykinin NK2 receptors in normal and altered rectal sensitivity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Responses of rat spinal neurons to distension of inflamed colon: role of tachykinin NK2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Effect of nepadutant, a neurokinin 2 tachykinin receptor antagonist, on immediate-early gene expression after trinitrobenzenesulfonic acid-induced colitis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Neurokinin B potentiates ATP-activated currents in rat DRG neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Implication of NK1 and NK2 receptors in rat colonic hypersecretion induced by interleukin 1 beta: role of nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Role of tachykinins in castor oil diarrhoea in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Human colonic anti-secretory activity of the potent NK(1) antagonist, SR140333: assessment of potential anti-diarrhoeal activity in food allergy and inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Dual and selective antagonism of neurokinin NK(1) and NK(2) receptor-mediated responses in human colon mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Neurokinin 1 and 2 receptors mediate cholera toxin secretion in rat jejunum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Differential alterations in tachykinin NK2 receptors in isolated colonic circular smooth muscle in inflammatory bowel disease and idiopathic chronic constipation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Roles of substance P receptors in human colon circular muscle: alterations in diverticular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Abnormal motility in patients with ulcerative colitis: the role of inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Substance P is a determinant of lethality in diet-induced hemorrhagic pancreatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Neurokinin-1 receptor antagonists CP-96,345 and L-733,060 protect mice from cytokine-mediated liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Sensory substance P-innervation of the urinary bladder: possible site of action of capsaicin in causing urine retention in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

The contribution of capsaicin-sensitive innervation to activation of the spinal vesico-vesical reflex in rats: relationship between substance P levels in the urinary bladder and the sensory-efferent function of capsaicin-sensitive sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Effect of capsaicin on micturition and associated reflexes in chronic spinal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Tachykinins as modulators of the micturition reflex in the central and peripheral nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Pharmacological evaluation of the role of cyclooxygenase isoenzymes on the micturition reflex following experimental cystitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Urodynamic effects induced by intravesical capsaicin in rats and hamsters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Prostanoids as local modulators of reflex micturition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Impaired response to chemical irritation of the urinary tract in mice with disruption of the preprotachykinin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Nitric oxide synthases and cyclophosphamide-induced cystitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Impaired IL-1beta-induced neutrophil accumulation in tachykinin NK1 receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Neurokinin B induces oedema formation in mouse lung via tachykinin receptor-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Immunologically induced histamine release from rat peritoneal mast cells is enhanced by low levels of substance P.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Substance P antagonist (CP-96,345) inhibits HIV-1 replication in human mononuclear phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

A non-peptide substance P antagonist down-regulates SP mRNA expression in human mononuclear phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Tachykinins and tachykinin receptors in bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Stress response, tachykinin, and cutaneous inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Upper airway neurogenic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

Tachykinin and kinin receptor antagonists: therapeutic perspectives in allergic airway disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

The immunomodulation of enteric neuromuscular function: implications for motility and inflammatory disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.3.343

21 January 2018

Identifiers

DOI

10.1517/14728222.7.3.343

1 reference

6 August 2017

1 reference