Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand (Q35143424)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499262%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand (English)

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28 January 2020

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28 January 2020

Stephan C Schürer

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28 January 2020

Theodore M Kamenecka

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28 January 2020

Laura A Solt

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28 January 2020

Naresh Kumar

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28 January 2020

Philippe Nuhant

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28 January 2020

Yongjun Wang

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28 January 2020

Janelle L Lauer

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28 January 2020

Jin Liu

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28 January 2020

Monica A Istrate

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28 January 2020

William R Roush

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28 January 2020

Dušica Vidović

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28 January 2020

Jihong Xu

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28 January 2020

Gail Wagoner

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28 January 2020

Paul D Drew

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28 January 2020

Patrick R Griffin

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28 January 2020

language of work or name

English

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publication date

17 April 2011

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28 January 2020

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28 January 2020

volume

472

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28 January 2020

issue

7344

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28 January 2020

page(s)

491-494

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Th17 and regulatory T cells in mediating and restraining inflammation

28 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Induction and effector functions of T(H)17 cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Th17 cell differentiation: the long and winding road

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3)

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Transcriptional regulation of Th17 cell differentiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Peroxisome proliferator-activated receptor-alpha agonist fenofibrate regulates IL-12 family cytokine expression in the CNS: relevance to multiple sclerosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

The orphan nuclear receptor Rev-erb alpha regulates circadian expression of plasminogen activator inhibitor type 1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

Identification of Reverb(alpha) as a novel ROR(alpha) target gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148894

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

13 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10075

7 January 2021

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10075

7 January 2021

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10075

7 January 2021

Evidence of GATA-3-dependent Th2 commitment during the in vivo immune response

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10075

7 January 2021

Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10075

7 January 2021

HD desktop: an integrated platform for the analysis and visualization of H/D exchange data

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10075

7 January 2021

Determination of amide hydrogen exchange by mass spectrometry: a new tool for protein structure elucidation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10075

7 January 2021

Identifiers

DOI

10.1038/NATURE10075

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499262%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 January 2020

0 references

1 reference

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28 January 2020

PubMed publication ID

21499262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499262%20AND%20SRC:MED&resulttype=core&format=json