Increased SOX2 gene copy number is associated with FGFR1 and PIK3CA gene gain in non-small cell lung cancer and predicts improved survival in early stage disease. (Q35149263)

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English	Increased SOX2 gene copy number is associated with FGFR1 and PIK3CA gene gain in non-small cell lung cancer and predicts improved survival in early stage disease.	scientific article

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14 March 2020

Increased SOX2 gene copy number is associated with FGFR1 and PIK3CA gene gain in non-small cell lung cancer and predicts improved survival in early stage disease (English)

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14 March 2020

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Luca Di Tommaso

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14 March 2020

Marta Scorsetti

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14 March 2020

Armando Santoro

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14 March 2020

Marileila Varella-Garcia

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Marileila Varella-Garcia

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14 March 2020

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Luca Toschi

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14 March 2020

Giovanna Finocchiaro

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14 March 2020

Teresa T Nguyen

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14 March 2020

Margaret C Skokan

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14 March 2020

Laura Giordano

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14 March 2020

Letizia Gianoncelli

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14 March 2020

Matteo Perrino

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14 March 2020

Licia Siracusano

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14 March 2020

Maurizio Infante

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14 March 2020

Marco Alloisio

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14 March 2020

Massimo Roncalli

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14 March 2020

Pasi A Jänne

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14 March 2020

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15 April 2014

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14 March 2020

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14 March 2020

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14 March 2020

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14 March 2020

e95303

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14 March 2020

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15 April 2014

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The prognostic value of SOX2 expression in non-small cell lung cancer: a meta-analysis

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13 July 2018

Fibroblast growth factor receptor 1 (FGFR1) copy number is an independent prognostic factor in non-small cell lung cancer

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13 July 2018

High SOX2 levels predict better outcome in non-small cell lung carcinomas

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13 July 2018

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer.

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13 July 2018

FGFR1 amplification in squamous cell carcinoma of the lung

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13 July 2018

Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models.

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13 July 2018

Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models

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13 July 2018

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

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13 July 2018

Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer.

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13 July 2018

Common PIK3CA mutants and a novel 3' UTR mutation are associated with increased sensitivity to saracatinib.

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13 July 2018

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

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13 July 2018

Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer

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13 July 2018

RNA polymerase III transcription in cancer: the BRF2 connection

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13 July 2018

Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer

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13 July 2018

Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.

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13 July 2018

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

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13 July 2018

Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma

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13 July 2018

Sox2 protein expression is an independent poor prognostic indicator in stage I lung adenocarcinoma.

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13 July 2018

SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas

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13 July 2018

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

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13 July 2018

Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients

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PIK3CA mutations and copy number gains in human lung cancers

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Cellular signaling by fibroblast growth factor receptors

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Pairing SOX off: with partners in the regulation of embryonic development

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Prognostic Value of Fibroblast Growth Factor Receptor 1 Gene Locus Amplification in Resected Lung Squamous Cell Carcinoma

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21 January 2018

SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer

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Biomarker Analyses and Final Overall Survival Results From a Phase III, Randomized, Open-Label, First-Line Study of Gefitinib Versus Carboplatin/Paclitaxel in Clinically Selected Patients With Advanced Non–Small-Cell Lung Cancer in Asia (IPASS)

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Morphologic and clinicopathologic features of lung squamous cell carcinomas expressing Sox2

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12 December 2020

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10.1371/JOURNAL.PONE.0095303

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14 March 2020

2014PLoSO...995303T

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14 March 2020

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