Pregnanolone sulfate promotes desensitization of activated NMDA receptors. (Q35148975)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474309%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Pregnanolone sulfate promotes desensitization of activated NMDA receptors (English)

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29 January 2020

1 reference

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29 January 2020

Cassandra L Kussius

1 reference

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29 January 2020

Navjot Kaur

series ordinal

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29 January 2020

language of work or name

English

0 references

publication date

1 May 2009

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29 January 2020

published in

Journal of Neuroscience

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29 January 2020

volume

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29 January 2020

issue

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29 January 2020

page(s)

6819-6827

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Kinetic basis of partial agonism at NMDA receptors

29 January 2020

cites work

1 reference

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Distinct gating modes determine the biphasic relaxation of NMDA receptor currents

28 July 2018

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Spontaneous and evoked glutamate release activates two populations of NMDA receptors with limited overlap

28 July 2018

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A nomenclature for ligand-gated ion channels

28 July 2018

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Activation of recombinant NR1/NR2C NMDA receptors

28 July 2018

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Linking exponential components to kinetic states in Markov models for single-channel gating

28 July 2018

1 reference

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Pregnenolone sulfate in the brain: a controversial neurosteroid

28 July 2018

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Neurosteroid regulation of central nervous system development

28 July 2018

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Neuroactive steroids and peripheral neuropathy.

28 July 2018

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The relevance of neuroactive steroids in schizophrenia, depression, and anxiety disorders

28 July 2018

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Neurosteroids as endogenous inhibitors of neuronal cell apoptosis in aging

28 July 2018

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NMDA receptor subunits: function and pharmacology.

28 July 2018

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Sulfated steroids as endogenous neuromodulators

28 July 2018

1 reference

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Neuroactive steroids and affective disorders

28 July 2018

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Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits

28 July 2018

1 reference

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20-oxo-5beta-pregnan-3alpha-yl sulfate is a use-dependent NMDA receptor inhibitor.

28 July 2018

1 reference

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Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles.

28 July 2018

1 reference

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N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease

28 July 2018

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Role of distinct NMDA receptor subtypes at central synapses

28 July 2018

1 reference

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Reaction mechanism determines NMDA receptor response to repetitive stimulation

28 July 2018

1 reference

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Neurosteroid biosynthesis in the human brain and its clinical implications

28 July 2018

1 reference

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Activation of NR1/NR2B NMDA receptors.

28 July 2018

1 reference

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Regulation of N-methyl-D-aspartate cytotoxicity by neuroactive steroids in rat cortical neurons.

28 July 2018

1 reference

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Neurosteroids: biochemistry and clinical significance

28 July 2018

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Neurosteroid modulation of recombinant ionotropic glutamate receptors.

28 July 2018

1 reference

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Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors

28 July 2018

1 reference

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Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids

28 July 2018

1 reference

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Neuroprotective activity of a new class of steroidal inhibitors of the N -methyl- d -aspartate receptor

28 July 2018

1 reference

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Single channel properties of cloned NMDA receptors in a human cell line: comparison with results from Xenopus oocytes

28 July 2018

1 reference

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N-methyl-D-aspartic acid receptor structure and function

28 July 2018

1 reference

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Steroid potentiation and inhibition of N-methyl-D-aspartate receptor-mediated intracellular Ca++ responses: structure-activity studies

28 July 2018

1 reference

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3 alpha-Hydroxy-5 beta-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

28 July 2018

1 reference

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On the stochastic properties of single ion channels

28 July 2018

1 reference

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Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells

28 July 2018

1 reference

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Glutamate activation of a single NMDA receptor-channel produces a cluster of channel openings.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Stochastic properties of ion channel openings and bursts in a membrane patch that contains two channels: evidence concerning the number of channels present when a record containing only single openings is observed.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

NMDA channel behavior depends on agonist affinity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Activation of N-methyl-D-aspartate receptors by L-glutamate in cells dissociated from adult rat hippocampus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Synthesis of C3, C5, and C7 pregnane derivatives and their effect on NMDA receptor responses in cultured rat hippocampal neurons.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Forebrain steroid levels fluctuate rapidly during social interactions

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Models and mechanistic insight

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

3alpha-OL-5-beta-pregnan-20-one hemisuccinate, a steroidal low-affinity NMDA receptor antagonist improves clinical rating scores in a rabbit multiple infarct ischemia model: synergism with tissue plasminogen activator

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

Gating reaction mechanisms for NMDA receptor channels.

27 September 2018

1 reference

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A primary culture system for biochemical analyses of neuronal proteins

27 September 2018

1 reference

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Inhibitory interactions of calcineurin (phosphatase 2B) and calmodulin on rat hippocampal NMDA receptors

27 September 2018

1 reference

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Modal gating of NMDA receptors and the shape of their synaptic response.

27 September 2018

1 reference

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Synthesis, regulation, and function of neurosteroids

27 September 2018

1 reference

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Calcineurin acts via the C-terminus of NR2A to modulate desensitization of NMDA receptors

27 September 2018

1 reference

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Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids

27 September 2018

1 reference

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Neurosteroids: beginning of the story

27 September 2018

1 reference

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Calcium-dependent inactivation of synaptic NMDA receptors in hippocampal neurons

27 September 2018

1 reference

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On the Kinetics of Large-Conductance Glutamate-Receptor Ion Channels in Rat Cerebellar Granule Neurons

16 November 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150747

16 November 2018

https://pubmed.ncbi.nlm.nih.gov/19474309

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.0281-09.2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474309%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474309%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

19474309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474309%20AND%20SRC:MED&resulttype=core&format=json