Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response (Q35130764)

6 August 2017

title

Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response (English)

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6 August 2017

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Michael L Dustin

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Hedi Mattoussi

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6 August 2017

Aaron R Clapp

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6 August 2017

Nadia Anikeeva

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6 August 2017

Tatiana Lebedeva

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6 August 2017

Ellen R Goldman

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6 August 2017

Yuri Sykulev

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6 August 2017

language of work or name

English

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publication date

31 October 2006

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

103

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6 August 2017

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6 August 2017

page(s)

16846-16851

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Quantum dot bioconjugates for imaging, labelling and sensing

6 August 2017

cites work

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ICAM-1 co-stimulates target cells to facilitate antigen presentation

13 July 2018

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CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers

13 July 2018

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CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse

13 July 2018

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Cytotoxic T lymphocytes form an antigen-independent ring junction

13 July 2018

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Self-assembled nanoscale biosensors based on quantum dot FRET donors

13 July 2018

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Generation and use of alternative multimers of peptide/MHC complexes

13 July 2018

1 reference

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Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands

13 July 2018

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The specificity of TCR/pMHC interaction

13 July 2018

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13 July 2018

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Receptor proximity, not intermolecular orientation, is critical for triggering T-cell activation

13 July 2018

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Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation

13 July 2018

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Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor

13 July 2018

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Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor

13 July 2018

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Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha

13 July 2018

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Multivalent structure of an alphabetaT cell receptor

13 July 2018

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13 July 2018

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Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines.

13 July 2018

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An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein

13 July 2018

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13 July 2018

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A hybrid quantum dot-antibody fragment fluorescence resonance energy transfer-based TNT sensor

21 January 2018

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Direct observation of ligand recognition by T cells.

21 January 2018

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Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

21 January 2018

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Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse

21 January 2018

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Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity

21 January 2018

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T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4.

21 January 2018

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Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.

21 January 2018

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Soluble HIV-specific T cell receptor: expression, purification and analysis of the specificity.

21 January 2018

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Can luminescent quantum dots be efficient energy acceptors with organic dye donors?

21 January 2018

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Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture

21 January 2018

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Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

21 January 2018

1 reference

12 December 2020

T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics

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12 December 2020

Major histocompatibility complex class I-intercellular adhesion molecule-1 association on the surface of target cells: implications for antigen presentation to cytotoxic T lymphocytes

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12 December 2020

Efficient detection and immunomagnetic sorting of specific T cells using multimers of MHC class I and peptide with reduced CD8 binding

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12 December 2020

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

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12 December 2020

Distinct molecular mechanisms account for the specificity of two different T-cell receptors

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0607771103

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6 August 2017

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6 August 2017

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