The dawning era of polymer therapeutics (Q35128900)

6 August 2017

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title

The dawning era of polymer therapeutics (English)

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6 August 2017

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3 January 2024

Ruth Duncan

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6 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12750738

3 January 2024

publication date

1 May 2003

1 reference

full work available at URL

6 August 2017

http://www.nature.com/articles/nrd1088.pdf

file format

Portable Document Format

1 reference

http://www.nature.com/articles/nrd1088

3 January 2024

1 reference

Nature Reviews Drug Discovery

3 January 2024

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

347-360

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Effect of pegylation on pharmaceuticals

6 August 2017

cites work

1 reference

Introduction and overview of peptide and protein pegylation

31 March 2020

1 reference

The routinization of intraperitoneal (intracavitary) chemotherapy and immunotherapy

31 March 2020

1 reference

31 March 2020

The origin of pegnology

1 reference

Gene therapy. Safer and virus-free?

31 March 2020

1 reference

Gene therapy progress and prospects: nonviral vectors.

31 March 2020

1 reference

Antibody-targeted polymer-bound drugs

31 March 2020

1 reference

Tat-conjugated synthetic macromolecules facilitate cytoplasmic drug delivery to human ovarian carcinoma cells

31 March 2020

1 reference

Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

31 March 2020

1 reference

Hyperbranched molecular nanocapsules: comparison of the hyperbranched architecture with the perfect linear analogue

31 March 2020

1 reference

A New Class of Polymers: Starburst-Dendritic Macromolecules

31 March 2020

1 reference

Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin

31 March 2020

1 reference

Synthesis, isolation and characterization of Plasmodium falciparum antigenic tetrabranched peptide dendrimers obtained by thiazolidine linkages

31 March 2020

1 reference

The emerging field of nanotube biotechnology

31 March 2020

1 reference

Preclinical safety evaluation of biotechnology-derived pharmaceuticals

31 March 2020

1 reference

Anti-HIV type 1 activity of sulfated derivatives of dextrin against primary viral isolates of HIV type 1 in lymphocytes and monocyte-derived macrophages

31 March 2020

1 reference

Reduction of the viral load of HIV-1 after the intraperitoneal administration of dextrin 2-sulphate in patients with AIDS

31 March 2020

1 reference

A placebo-controlled, double-blind prospective study in healthy female volunteers of dextrin sulphate gel: a novel potential intravaginal virucide

31 March 2020

1 reference

Copolymer 1: from basic research to clinical application

31 March 2020

1 reference

Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group

31 March 2020

1 reference

RenaGel, a nonabsorbed calcium- and aluminum-free phosphate binder, lowers serum phosphorus and parathyroid hormone. The RenaGel Study Group

31 March 2020

1 reference

Polysialic acids: potential in drug delivery

31 March 2020

1 reference

Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats.

31 March 2020

1 reference

Micro-MR angiography of normal and intratumoral vessels in mice using dedicated intravascular MR contrast agents with high generation of polyamidoamine dendrimer core: reference to pharmacokinetic properties of dendrimer-based MR contrast agents

31 March 2020

1 reference

Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier

31 March 2020

1 reference

Biocompatibility of N-(2-hydroxypropyl) methacrylamide copolymers containing adriamycin. Immunogenicity, and effect on haematopoietic stem cells in bone marrow in vivo and mouse splenocytes and human peripheral blood lymphocytes in vitro

31 March 2020

1 reference

Reduced cardiotoxicity of doxorubicin given in the form of N-(2-hydroxypropyl)methacrylamide conjugates: and experimental study in the rat

31 March 2020

1 reference

The further evolution of biotech

31 March 2020

1 reference

Therapeutic antibodies for human diseases at the dawn of the twenty-first century

31 March 2020

1 reference

Stabilization of substances in circulation

31 March 2020

1 reference

Polyethylene glycol modification: relevance of improved methodology to tumour targeting

31 March 2020

1 reference

Chemistry for peptide and protein PEGylation

31 March 2020

1 reference

Therapeutic antibody fragments with prolonged in vivo half-lives

31 March 2020

1 reference

Enzymatic procedure for site-specific pegylation of proteins

31 March 2020

1 reference

Drug delivery systems employing 1,6-elimination: releasable poly(ethylene glycol) conjugates of proteins

31 March 2020

1 reference

Adenosine deaminase deficiency with late onset of recurrent infections: response to treatment with polyethylene glycol-modified adenosine deaminase

31 March 2020

1 reference

Mono-N-terminal poly(ethylene glycol)-protein conjugates

31 March 2020

1 reference

Use of peginterferon alfa-2a (40 KD) (Pegasys) for the treatment of hepatitis C.

31 March 2020

1 reference

Structural and biological characterization of pegylated recombinant interferon alpha-2b and its therapeutic implications

31 March 2020

1 reference

Pegylated interferon alfa-2b treatment for patients with solid tumors: a phase I/II study.

31 March 2020

1 reference

Commentary. Lysosomotropic agents

31 March 2020

1 reference

Drug-targeting strategies in cancer therapy

31 March 2020

1 reference

Polymer conjugates. Pharmacokinetic considerations for design and development

31 March 2020

1 reference

Tumour tropism and anti-cancer efficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma

31 March 2020

1 reference

HPMA copolymer platinates as novel antitumour agents: in vitro properties, pharmacokinetics and antitumour activity in vivo

31 March 2020

1 reference

Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl) methacrylamide copolymers

31 March 2020

1 reference

New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties

31 March 2020

1 reference

New types of synthetic infusion solutions. III. Elimination and retention of poly-[N-(2-hydroxypropyl)methacrylamide] in a test organism

31 March 2020

1 reference

HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action

31 March 2020

1 reference

Population pharmacokinetics in phase I drug development: a phase I study of PK1 in patients with solid tumours

31 March 2020

1 reference

Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendent galactosamine residues after intravenous administration to rats

31 March 2020

1 reference

Carbohydrate-Specific Receptors of the Liver

31 March 2020

1 reference

Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine

31 March 2020

1 reference

Phase I clinical and pharmacokinetic study of PNU166945, a novel water-soluble polymer-conjugated prodrug of paclitaxel

31 March 2020

1 reference

A phase I and pharmacokinetic study of MAG-CPT, a water-soluble polymer conjugate of camptothecin

31 March 2020

1 reference

Effective drug delivery by PEGylated drug conjugates

31 March 2020

1 reference

HPMA copolymers platinates containing dicarboxylato ligands. Preparation, characterisation and in vitro and in vivo evaluation

31 March 2020

1 reference

Anthracycline antibiotics non-covalently incorporated into the block copolymer micelles: in vivo evaluation of anti-cancer activity.

31 March 2020

1 reference

Development of the polymer micelle carrier system for doxorubicin

31 March 2020

1 reference

Delivery of molecular and cellular medicine to solid tumors

31 March 2020

1 reference

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

31 March 2020

1 reference

Gene transfer with lipospermines and polyethylenimines

31 March 2020

1 reference

Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments

31 March 2020

1 reference

Overcoming the nuclear barrier: cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation

31 March 2020

1 reference

Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo

31 March 2020

1 reference

Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application

31 March 2020

1 reference

Induction of potent human immunodeficiency virus type 1-specific T-cell-restricted immunity by genetically modified dendritic cells

31 March 2020

1 reference

Molecular engineering of proteins and polymers for targeting and intracellular delivery of therapeutics

31 March 2020

1 reference

PDEPT: polymer-directed enzyme prodrug therapy. 2. HPMA copolymer-beta-lactamase and HPMA copolymer-C-Dox as a model combination

31 March 2020

1 reference

Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to clinic

31 March 2020

1 reference

A chemical adaptor system designed to link a tumor-targeting device with a prodrug and an enzymatic trigger

31 March 2020

1 reference

Clinical translation of angiogenesis inhibitors

31 March 2020

1 reference

Designing macromolecules for therapeutic applications: polyester dendrimer-poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture

31 March 2020

1 reference

Biological applications of dendrimers

31 March 2020

1 reference

Anionic PAMAM dendrimers rapidly cross adult rat intestine in vitro: a potential oral delivery system?

31 March 2020

1 reference

Biodegradable, elastic shape-memory polymers for potential biomedical applications

31 March 2020

1 reference

Fulfilling the promise: drug discovery in the post-genomic era.

31 March 2020

1 reference

The next frontier of molecular medicine: delivery of therapeutics.

31 March 2020

1 reference

Ligand-targeted therapeutics in anticancer therapy

31 March 2020

1 reference

Delivery of molecular and cellular medicine to solid tumors

31 March 2020

1 reference

Anti-Kaposi's sarcoma and antiangiogenic activities of sulfated dextrins

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Drug-polymer conjugates: potential for improved chemotherapy

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

6387

Y Matsumura

1986

1 reference

3 January 2024

103

2404

C Li

1998

1 reference

3 January 2024

121

159

J Wu

1998

1 reference

3 January 2024

130

6124

F Vernejoul

2002

1 reference

3 January 2024

150

2114

K Iwai

1984

1 reference

3 January 2024

154

OC8

A Mukherjee

2002

1 reference

3 January 2024

Identifiers

DOI

10.1038/NRD1088

1 reference

Dimensions Publication ID

6 August 2017

1010845241

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