Enzymatic Defects Underlying Hereditary Glutamate Cysteine Ligase Deficiency Are Mitigated by Association of the Catalytic and Regulatory Subunits (Q35124791)

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scientific article published on June 29, 2011

Language	Label	Description	Also known as
English	Enzymatic Defects Underlying Hereditary Glutamate Cysteine Ligase Deficiency Are Mitigated by Association of the Catalytic and Regulatory Subunits	scientific article published on June 29, 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunits (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Enzymatic Defects Underlying Hereditary Glutamate Cysteine Ligase Deficiency Are Mitigated by Association of the Catalytic and Regulatory Subunits (English)

1 reference

10.1021/BI200708W

https://api.crossref.org/works/10.1021/BI200708W

4 December 2024

catalytic domain

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21657237

4 December 2024

author name string

Melanie Neely Willis

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Yilin Liu

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Heejeong Kim

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Jaekwon Lee

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Ekaterina I. Biterova

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21657237

4 December 2024

Melanie A. Simpson

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21657237

4 December 2024

Joseph J. Barycki

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21657237

4 December 2024

language of work or name

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publication date

29 June 2011

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6 August 2017

full work available at URL

https://europepmc.org/articles/pmc3142541?pdf=render

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21657237

4 December 2024

https://europepmc.org/articles/PMC3142541

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21657237

4 December 2024

https://europepmc.org/articles/PMC3142541?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21657237

4 December 2024

https://doi.org/10.1021/bi200708w

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21657237

4 December 2024

https://pubs.acs.org/doi/pdf/10.1021/bi200708w

1 reference

10.1021/BI200708W

https://api.crossref.org/works/10.1021/BI200708W

4 December 2024

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

50

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

29

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

6508-6517

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Posttranslational modification and regulation of glutamate-cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

The red blood cell proteome and interactome: an update

1 reference

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28 July 2018

Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Regulation of glutathione synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Chronic non-spherocytic hemolytic anemia associated with severe neurological disease due to gamma-glutamylcysteine synthetase deficiency in a patient of Moroccan origin

1 reference

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28 July 2018

Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels

1 reference

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28 July 2018

The importance of glutathione in human disease

1 reference

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28 July 2018

A novel missense mutation in the gamma-glutamylcysteine synthetase catalytic subunit gene causes both decreased enzymatic activity and glutathione production

1 reference

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28 July 2018

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response

1 reference

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28 July 2018

High-density miniaturized thermal shift assays as a general strategy for drug discovery

1 reference

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28 July 2018

Glutathione in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

A genetic investigation of the essential role of glutathione: mutations in the proline biosynthesis pathway are the only suppressors of glutathione auxotrophy in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Glutathione synthesis is essential for mouse development but not for cell growth in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

A missense mutation in the heavy subunit of gamma-glutamylcysteine synthetase gene causes hemolytic anemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

The molecular basis of a case of gamma-glutamylcysteine synthetase deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Identification of an important cysteine residue in human glutamate-cysteine ligase catalytic subunit by site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Regulation of gamma-glutamylcysteine synthetase by protein phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Mutations in the glutathione synthetase gene cause 5-oxoprolinuria

1 reference

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28 July 2018

Hydrogen peroxide increases the activity of gamma-glutamylcysteine synthetase in cultured Chinese hamster V79 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Three cases of hereditary nonspherocytic hemolytic anemia associated with red blood cell glutathione deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142541

28 July 2018

Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues

1 reference

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Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure

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28 July 2018

1 reference

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Amino acid sequence of rat kidney gamma-glutamylcysteine synthetase

1 reference

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Molecular cloning of the gamma-glutamylcysteine synthetase gene of Saccharomyces cerevisiae

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Structural Basis for Feedback and Pharmacological Inhibition of Saccharomyces cerevisiae Glutamate Cysteine Ligase

1 reference

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Mechanistic Details of Glutathione Biosynthesis Revealed by Crystal Structures of Saccharomyces cerevisiae Glutamate Cysteine Ligase

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1 reference

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Expression and characterization of human glutamate-cysteine ligase

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Evaluation of the micromethod for determination of glutathione using enzymatic cycling and Ellman's reagent

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Catalytic and regulatory properties of the heavy subunit of rat kidney gamma-glutamylcysteine synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21657237

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based on heuristic

inferred from PubMed ID database lookup

Endogenous glutathione conjugates: occurrence and biological functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21657237

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based on heuristic

inferred from PubMed ID database lookup

Interaction between the catalytic and modifier subunits of glutamate-cysteine ligase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21657237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological Reviews

4

50

335

author name string

Wang W.

publication date

1998

1 reference

10.1021/BI200708W

https://api.crossref.org/works/10.1021/BI200708W

4 December 2024

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10.1021/BI200708W

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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