The molecular pathogenesis of head and neck cancer (Q35111736)

6 August 2017

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title

The molecular pathogenesis of head and neck cancer (English)

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6 August 2017

main subject

head and neck carcinoma

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inferred from title

author

Jennifer Rubin Grandis

series ordinal

object named as

Jennifer R Grandis

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6 August 2017

Jonah D Klein

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6 August 2017

language of work or name

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9 January 2010

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Cancer Biology and Therapy

6 August 2017

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

1-7

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Human papillomavirus in head and neck cancer: its role in pathogenesis and clinical implications

6 August 2017

cites work

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Current and potential inflammation targeted therapies in head and neck cancer

9 July 2018

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HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Dysregulated molecular networks in head and neck carcinogenesis

9 July 2018

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Head and neck cancer: an evolving treatment paradigm

9 July 2018

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9 July 2018

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9 July 2018

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Molecular pathogenesis of head and neck cancers

9 July 2018

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Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma.

9 July 2018

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Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signaling

9 July 2018

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Dissecting the Akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative.

9 July 2018

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Insulin-like growth factor receptor as a therapeutic target in head and neck cancer

9 July 2018

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9 July 2018

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The epidemiology and risk factors of head and neck cancer: a focus on human papillomavirus

9 July 2018

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9 July 2018

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9 July 2018

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Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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STAT3 as a therapeutic target in head and neck cancer

9 July 2018

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Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

9 July 2018

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Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck

9 July 2018

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The ATM/p53 pathway is commonly targeted for inactivation in squamous cell carcinoma of the head and neck (SCCHN) by multiple molecular mechanisms

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Tumor cell invasion and survival in head and neck cancer

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Tumor cell and endothelial cell therapy of oral cancer by dual tyrosine kinase receptor blockade

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C.

9 July 2018

1 reference

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Met, metastasis, motility and more

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

c-Met: structure, functions and potential for therapeutic inhibition

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Alterations of p16(INK4a) and p14(ARF) in patients with severe oral epithelial dysplasia.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma

9 July 2018

1 reference

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9 July 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Dual silencing of epidermal growth factor and insulin-like growth factor 1 receptors significantly limits growth of nasopharyngeal carcinoma in nude mice.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Insulin-like growth factor-I receptor signaling pathway induces resistance to the apoptotic activities of SCH66336 (lonafarnib) through Akt/mammalian target of rapamycin-mediated increases in survivin expression

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Signal transducers and activators of transcription 3 up-regulates vascular endothelial growth factor production and tumor angiogenesis in head and neck squamous cell carcinoma.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Cyclin D1 and p16 alterations in advanced premalignant lesions of the upper aerodigestive tract: role in response to chemoprevention and cancer development.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Phase II Study of Lapatinib in Recurrent or Metastatic Epidermal Growth Factor Receptor and/or erbB2 Expressing Adenoid Cystic Carcinoma and Non–Adenoid Cystic Carcinoma Malignant Tumors of the Salivary Glands

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

Alcohol Drinking in Never Users of Tobacco, Cigarette Smoking in Never Drinkers, and the Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium

8 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138532

A Novel Gene Expression Profile in Lymphatics Associated with Tumor Growth and Nodal Metastasis

8 December 2018

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12 December 2020

Identification of oral cancer cell-induced changes in gene expression profile of lymphatic endothelial cell

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12 December 2020

Single-nucleotide polymorphisms at the TP53-binding or responsive promoter regions of BAX and BCL2 genes and risk of squamous cell carcinoma of the head and neck

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12 December 2020

Retinoic acid normalizes the increased gene transcription rate of TGF-alpha and EGFR in head and neck cancer cell lines

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12 December 2020

Pattern of amplification and overexpression of the eukaryotic initiation factor 4E gene in solid tumor

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12 December 2020

Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo

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12 December 2020

Phase I/II trial of erlotinib and cisplatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: a Princess Margaret Hospital phase II consortium and National Cancer Institute of Canada Clinical Trials Group Study

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12 December 2020

Identifiers

DOI

10.4161/CBT.9.1.10905

1 reference

6 August 2017

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6 August 2017

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