Inflammasome activation in response to the Yersinia type III secretion system requires hyperinjection of translocon proteins YopB and YopD. (Q35111107)

6 August 2017

title

Inflammasome activation in response to the Yersinia type III secretion system requires hyperinjection of translocon proteins YopB and YopD. (English)

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6 August 2017

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6 August 2017

Erin E Zwack

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6 August 2017

Annelise G Snyder

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6 August 2017

Meghan A Wynosky-Dolfi

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6 August 2017

Gordon Ruthel

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6 August 2017

Naomi H Philip

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6 August 2017

Melanie M Marketon

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6 August 2017

James B Bliska

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6 August 2017

Igor E Brodsky

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6 August 2017

language of work or name

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17 February 2015

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6 August 2017

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

e02095-14

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IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM.

6 August 2017

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9 July 2018

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9 July 2018

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The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome

9 July 2018

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9 July 2018

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Impact of host membrane pore formation by the Yersinia pseudotuberculosis type III secretion system on the macrophage innate immune response

9 July 2018

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The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing

9 July 2018

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YopK controls both rate and fidelity of Yop translocation

9 July 2018

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9 July 2018

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Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens

9 July 2018

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Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

9 July 2018

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TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria

9 July 2018

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9 July 2018

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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

9 July 2018

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ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

9 July 2018

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Non-canonical inflammasome activation targets caspase-11

9 July 2018

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The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function

9 July 2018

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YopK regulates the Yersinia pestis type III secretion system from within host cells

9 July 2018

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Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing

9 July 2018

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A role for mitochondria in NLRP3 inflammasome activation

9 July 2018

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Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.

9 July 2018

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Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

9 July 2018

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A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system

9 July 2018

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Influenza virus activates inflammasomes via its intracellular M2 ion channel

9 July 2018

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Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

9 July 2018

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Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells

9 July 2018

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Yersinia pestis can bypass protective antibodies to LcrV and activation with gamma interferon to survive and induce apoptosis in murine macrophages

9 July 2018

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Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases

9 July 2018

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9 July 2018

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NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens

9 July 2018

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The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.

9 July 2018

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Inflammasome recognition of influenza virus is essential for adaptive immune responses

9 July 2018

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9 July 2018

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

9 July 2018

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Reduced secretion of YopJ by Yersinia limits in vivo cell death but enhances bacterial virulence

9 July 2018

1 reference

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Pseudomonas aeruginosa activates caspase 1 through Ipaf

9 July 2018

1 reference

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Type III secretion translocation pores of Yersinia enterocolitica trigger maturation and release of pro-inflammatory IL-1beta

9 July 2018

1 reference

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Macrophage activation redirects yersinia-infected host cell death from apoptosis to caspase-1-dependent pyroptosis

9 July 2018

1 reference

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A rationale for repression and/or loss of motility by pathogenic Yersinia in the mammalian host

9 July 2018

1 reference

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Minimal YopB and YopD translocator secretion by Yersinia is sufficient for Yop-effector delivery into target cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337566

Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

9 July 2018

1 reference

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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

9 July 2018

1 reference

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Cryopyrin activates the inflammasome in response to toxins and ATP

9 July 2018

1 reference

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Gout-associated uric acid crystals activate the NALP3 inflammasome

9 July 2018

1 reference

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

9 July 2018

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Tetratricopeptide repeats in the type III secretion chaperone, LcrH: their role in substrate binding and secretion

9 July 2018

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Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis

9 July 2018

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The response regulator PhoP of Yersinia pseudotuberculosis is important for replication in macrophages and for virulence

9 July 2018

1 reference

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The YopD translocator of Yersinia pseudotuberculosis is a multifunctional protein comprised of discrete domains.

9 July 2018

1 reference

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

9 July 2018

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Innate immune recognition

9 July 2018

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YopD and LcrH regulate expression of Yersinia enterocolitica YopQ by a posttranscriptional mechanism and bind to yopQ RNA.

9 July 2018

1 reference

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Pro-inflammatory programmed cell death

9 July 2018

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YopB of Yersinia enterocolitica is essential for YopE translocation

9 July 2018

1 reference

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Insertion of a Yop translocation pore into the macrophage plasma membrane by Yersinia enterocolitica: requirement for translocators YopB and YopD, but not LcrG.

9 July 2018

1 reference

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The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1

9 July 2018

1 reference

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YopD of Yersinia pseudotuberculosis is translocated into the cytosol of HeLa epithelial cells: evidence of a structural domain necessary for translocation

9 July 2018

1 reference

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YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-alpha production and downregulation of the MAP kinases p38 and JNK.

9 July 2018

1 reference

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YopD of Yersinia pestis plays a role in negative regulation of the low-calcium response in addition to its role in translocation of Yops

9 July 2018

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Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death

9 July 2018

1 reference

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YopK of Yersinia pseudotuberculosis controls translocation of Yop effectors across the eukaryotic cell membrane

9 July 2018

1 reference

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The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cells

9 July 2018

1 reference

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Translocation of the Yersinia YopE and YopH virulence proteins into target cells is mediated by YopB and YopD.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337566

Individual chaperones required for Yop secretion by Yersinia

9 July 2018

1 reference

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Translocation of a hybrid YopE-adenylate cyclase from Yersinia enterocolitica into HeLa cells

9 July 2018

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Approaching the asymptote? Evolution and revolution in immunology

9 July 2018

1 reference

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Endoplasmic reticulum stress is sufficient for the induction of IL-1β production via activation of the NF-κB and inflammasome pathways.

9 July 2018

1 reference

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The invasion-associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cell

27 September 2018

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Cytosolic detection of flagellin: a deadly twist

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25691590

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MBIO.02095-14

1 reference

6 August 2017

1 reference

6 August 2017

1 reference