Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. (Q35101294)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186369%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin (English)

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18 January 2020

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18 January 2020

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18 January 2020

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18 January 2020

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18 January 2020

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18 January 2020

Philipp E Scherer

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18 January 2020

Scott A Summers

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18 January 2020

William L Holland

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18 January 2020

Russell A Miller

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18 January 2020

Zhao V Wang

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18 January 2020

Hai H Bui

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18 January 2020

Kathryn E Davis

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18 January 2020

Benjamin T Bikman

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18 January 2020

Mark R Wade

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18 January 2020

Vincent M Tenorio

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18 January 2020

Ming-Shang Kuo

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18 January 2020

Joseph T Brozinick

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18 January 2020

Bei B Zhang

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18 January 2020

language of work or name

English

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publication date

26 December 2010

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18 January 2020

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18 January 2020

volume

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18 January 2020

issue

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18 January 2020

page(s)

55-63

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Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

18 January 2020

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PAQRs: a counteracting force to ceramides?

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9 July 2018

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9 July 2018

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9 July 2018

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Probing the mechanism of FET3 repression by Izh2p overexpression

9 July 2018

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9 July 2018

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Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity

9 July 2018

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9 July 2018

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Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity

9 July 2018

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Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

9 July 2018

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The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

9 July 2018

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9 July 2018

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Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Erythropoietin protects cardiomyocytes from apoptosis via up-regulation of endothelial nitric oxide synthase

27 September 2018

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Substrate specificity of rat brain ceramidase

27 September 2018

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Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

27 September 2018

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Inflammatory mechanisms in diabetes: lessons from the beta-cell

16 November 2018

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12 December 2020

Variation of heat shock protein 70 through the cell cycle in HL-60 cells and its relationship to apoptosis

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12 December 2020

The sphingosine kinase-sphingosine-1-phosphate axis is a determinant of mast cell function and anaphylaxis

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12 December 2020

Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes

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12 December 2020

Quantitative determination of ceramide using diglyceride kinase

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12 December 2020

Disruption of adiponectin causes insulin resistance and neointimal formation

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7 January 2021

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

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7 January 2021

De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway

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7 January 2021

Disordered lipid metabolism and the pathogenesis of insulin resistance

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7 January 2021

Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

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7 January 2021

Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling

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7 January 2021

Inhibitory actions of ceramide upon PKC-epsilon/ERK interactions

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7 January 2021

Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.

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Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains

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Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.

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Identifiers

DOI

10.1038/NM.2277

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186369%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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18 January 2020

PubMed publication ID

21186369

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