Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression (Q35106230)

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English	Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 August 2017

Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression (English)

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Europe PubMed Central

PubMed publication ID

6 August 2017

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Nadine C Olthof

1

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8 June 2020

Ernst-Jan M Speel

2

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8 June 2020

Jutta Kolligs

3

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8 June 2020

Annick Haesevoets

4

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8 June 2020

Mieke Henfling

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8 June 2020

Frans C S Ramaekers

6

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8 June 2020

Simon F Preuss

7

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8 June 2020

Ulrike Wieland

9

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8 June 2020

Steffi Silling

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8 June 2020

Wan L Lam

11

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8 June 2020

Bernd Kremer

13

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8 June 2020

Jens-P Klussmann

14

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8 June 2020

Christian U Huebbers

15

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8 June 2020

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24 February 2014

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6 August 2017

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8 June 2020

9

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8 June 2020

2

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8 June 2020

e88718

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8 June 2020

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Creative Commons Attribution 4.0 International

24 February 2014

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April 2022 Public Data File from Crossref

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Multiplex Identification of Human Papillomavirus 16 DNA Integration Sites in Cervical Carcinomas

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Integration of HPV6 and downregulation of AKR1C3 expression mark malignant transformation in a patient with juvenile-onset laryngeal papillomatosis

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Preferential sites for the integration and disruption of human papillomavirus 16 in cervical lesions

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Next-generation treatment strategies for human papillomavirus-related head and neck squamous cell carcinoma: where do we go?

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Association of FANCC and PTCH1 with the development of early dysplastic lesions of the head and neck

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UniProt Knowledgebase: a hub of integrated protein data

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HDAC2 promotes cell migration/invasion abilities through HIF-1α stabilization in human oral squamous cell carcinoma.

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Global cancer statistics

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Characterization of the Methylation Patterns in Human Papillomavirus Type 16 Viral DNA in Head and Neck Cancers

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9 July 2018

Human papillomavirus type 16 (HPV-16) genomes integrated in head and neck cancers and in HPV-16-immortalized human keratinocyte clones express chimeric virus-cell mRNAs similar to those found in cervical cancers

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9 July 2018

Frequent genomic structural alterations at HPV insertion sites in cervical carcinoma

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9 July 2018

Human papillomavirus E6 and E7 oncoproteins as risk factors for tumorigenesis

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9 July 2018

E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells

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9 July 2018

Genetic signatures of HPV-related and unrelated oropharyngeal carcinoma and their prognostic implications

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9 July 2018

The majority of viral-cellular fusion transcripts in cervical carcinomas cotranscribe cellular sequences of known or predicted genes

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9 July 2018

Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins

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9 July 2018

Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma

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9 July 2018

Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world

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9 July 2018

Human papillomavirus type 16 integration in cervical carcinoma in situ and in invasive cervical cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3933331

9 July 2018

Regulation of human papillomavirus type 16 E7 activity through direct protein interaction with the E2 transcriptional activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3933331

9 July 2018

Clonal history of papillomavirus-induced dysplasia in the female lower genital tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3933331

9 July 2018

Global cancer statistics, 2002

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9 July 2018

A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5–8

1 reference

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9 July 2018

Oncogenic human papillomavirus DNA loads in human immunodeficiency virus-positive women with high-grade cervical lesions are strongly elevated

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3933331

9 July 2018

Expression of p16 protein identifies a distinct entity of tonsillar carcinomas associated with human papillomavirus

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9 July 2018

Prevalence, distribution, and viral load of human papillomavirus 16 DNA in tonsillar carcinomas

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3933331

9 July 2018

Detection of integrated papillomavirus sequences by ligation-mediated PCR (DIPS-PCR) and molecular characterization in cervical cancer cells

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9 July 2018

Complex genomic rearrangement within the 12q15 multiple aberration region induced by integrated human papillomavirus 18 in a cervical carcinoma cell line.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3933331

9 July 2018

In vitro experimental systems for HPV: epithelial raft cultures for investigations of viral reproduction and pathogenesis and for genetic analyses of viral proteins and regulatory sequences

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9 July 2018

Integration of human papillomavirus type 16 DNA into the human genome leads to increased stability of E6 and E7 mRNAs: implications for cervical carcinogenesis

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9 July 2018

Human papillomavirus type 16 DNA sequence

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9 July 2018

Differential methylation of E2 binding sites in episomal and integrated HPV 16 genomes in preinvasive and invasive cervical lesions.

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27 September 2018

Chromosome stability in tonsillar squamous cell carcinoma is associated with HPV16 integration and indicates a favorable prognosis

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27 September 2018

Loss of gene function as a consequence of human papillomavirus DNA integration.

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27 September 2018

Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas.

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27 September 2018

Type-dependent integration frequency of human papillomavirus genomes in cervical lesions.

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27 September 2018

Human papillomavirus-16 DNA methylation patterns support a causal association of the virus with oral squamous cell carcinomas

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27 September 2018

Tissue distribution of human papillomavirus 16 DNA integration in patients with tonsillar carcinoma

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27 September 2018

A comprehensive analysis of HPV integration loci in anogenital lesions combining transcript and genome-based amplification techniques.

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27 September 2018

Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control.

1 reference

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27 September 2018

Detection of high-risk cervical intraepithelial neoplasia and cervical cancer by amplification of transcripts derived from integrated papillomavirus oncogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3933331

27 September 2018

Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0088718

21 January 2018

Prevalence and physical status of human papillomavirus in squamous cell carcinomas of the head and neck

1 reference

https://pubmed.ncbi.nlm.nih.gov/24586376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of beta-human papillomavirus DNA by real-time PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/24586376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human papillomavirus type 16 is episomal and a high viral load may be correlated to better prognosis in tonsillar cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24586376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integration of the HPV16 genome does not invariably result in high levels of viral oncogene transcripts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24586376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase 2 expression predicts poorer prognosis in oral cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24586376

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0088718

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24586376%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

2014PLoSO...988718O

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24586376%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24586376%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

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