Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells. (Q35092701)

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20 January 2020

title

Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells (English)

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20 January 2020

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20 January 2020

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20 January 2020

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20 January 2020

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20 January 2020

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20 January 2020

Y Ragazzoni

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20 January 2020

T De Luca

series ordinal

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publication date

14 January 2011

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Cell Death & Differentiation

20 January 2020

published in

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volume

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issue

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20 January 2020

page(s)

1024-1035

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Retracted: Bcl-2 Regulates HIF-1α Protein Stabilization in Hypoxic Melanoma Cells via the Molecular Chaperone HSP90

20 January 2020

cites work

1 reference

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Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands

9 July 2018

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Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway

9 July 2018

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Nur77 upregulates HIF-alpha by inhibiting pVHL-mediated degradation

9 July 2018

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Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signaling

9 July 2018

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Downregulation of BCL-2 induces downregulation of carbonic anhydrase IX, vascular endothelial growth factor, and pAkt and induces radiation sensitization

9 July 2018

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The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability

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RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha

9 July 2018

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Bcl2 suppresses DNA repair by enhancing c-Myc transcriptional activity

9 July 2018

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Involvement of PI3K and MAPK signaling in bcl-2-induced vascular endothelial growth factor expression in melanoma cells

9 July 2018

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Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth.

9 July 2018

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The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)

9 July 2018

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Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity

9 July 2018

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Deletion of the BH1 domain of Bcl-2 accelerates apoptosis by acting in a dominant negative fashion

9 July 2018

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The Bcl2 family: regulators of the cellular life-or-death switch

9 July 2018

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Bcl-2 overexpression in human melanoma cells increases angiogenesis through VEGF mRNA stabilization and HIF-1-mediated transcriptional activity

9 July 2018

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Interferon-gamma sensitizes colonic epithelial cell lines to physiological and therapeutic inducers of colonocyte apoptosis

9 July 2018

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Bcl-2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line.

9 July 2018

1 reference

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bcl-2 over-expression enhances NF-kappaB activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells

9 July 2018

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BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

9 July 2018

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Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis

9 July 2018

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The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4

9 July 2018

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Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

9 July 2018

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Bcl-2 targets the protein kinase Raf-1 to mitochondria

9 July 2018

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Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis

9 July 2018

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Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

9 July 2018

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Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines.

9 July 2018

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Evidence for alpha-helical conformation of an essential N-terminal region in the human Bcl2 protein.

27 September 2018

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Bcl-2, via Its BH4 Domain, Blocks Apoptotic Signaling Mediated by Mitochondrial Ras

27 September 2018

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Crossref

https://api.crossref.org/works/10.1038%2FCDD.2010.175

TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo

21 January 2018

1 reference

12 December 2020

Antiangiogenic effect of TW37, a small-molecule inhibitor of Bcl-2

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12 December 2020

Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression

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12 December 2020

Bcl-2 Orchestrates a Cross-talk between Endothelial and Tumor Cells that Promotes Tumor Growth

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12 December 2020

Expression of bcl-2 is associated with microvessel density in olfactory neuroblastoma

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12 December 2020

Identifiers

DOI

10.1038/CDD.2010.175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21233846%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

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20 January 2020

PubMed publication ID

21233846

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21233846%20AND%20SRC:MED&resulttype=core&format=json