Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma (Q35095028)

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English	Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma	scientific article

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24531327

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6 August 2017

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Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma (English)

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Jay Gunawardana

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Jay Gunawardana

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Karen Leroy

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Corinne Haioun

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Randy D Gascoyne

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Randy D Gascoyne

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Joseph M Connors

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Joseph M Connors

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Lisa M Rimsza

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Lisa M Rimsza

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Sohrab P. Shah

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Sohrab P Shah

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Marco Marra

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Marco A Marra

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Kerry J Savage

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Kerry J Savage

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Christian Steidl

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Christian Steidl

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Anja Mottok

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Anja Mottok

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Susana Ben-Neriah

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Susana Ben-Neriah

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Sanja Rogic

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Sanja Rogic

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Merrill Boyle

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Merrill Boyle

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Fong Chun Chan

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Fong Chun Chan

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Bruce W Woolcock

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Bruce Woolcock

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Robert Kridel

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Robert Kridel

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6 August 2017

Philippe Gaulard

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Philippe Gaulard

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6 August 2017

author name string

Adèle Telenius

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3

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6 August 2017

King L Tan

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6

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6 August 2017

Raymond S Lim

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9

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6 August 2017

Chrystelle Guiter

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13

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6 August 2017

language of work or name

English

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publication date

16 February 2014

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6 August 2017

number of pages

7

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published in

Nature Genetics

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6 August 2017

volume

46

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6 August 2017

issue

4

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24531327

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6 August 2017

page(s)

329-335

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24531327

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6 August 2017

cites work

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase

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PTP1B: a double agent in metabolism and oncogenesis

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STAT3 is constitutively activated in Hodgkin cell lines

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12 December 2020

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Feature-based classifiers for somatic mutation detection in tumour-normal paired sequencing data

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Overexpression of the tyrosine phosphatase PTP1B is associated with human ovarian carcinomas

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Primary mediastinal B-cell lymphoma.

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Oncogenic kinase signalling

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Primary mediastinal large B-cell lymphoma

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Mechanism of multidrug recognition by MDR1/ABCB1.

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Protein-tyrosine phosphatases and cancer

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Genetic ablation of protein tyrosine phosphatase 1B accelerates lymphomagenesis of p53-null mice through the regulation of B-cell development

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The molecular pathogenesis of primary mediastinal large B-cell lymphoma

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12 December 2020

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nFuse: discovery of complex genomic rearrangements in cancer using high-throughput sequencing

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PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24531327

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12 December 2020

based on heuristic

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Mutation analysis of the tyrosine phosphatase PTPN2 in Hodgkin's lymphoma and T-cell non-Hodgkin's lymphoma

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24531327

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based on heuristic

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Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

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Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphoma

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Altered distribution and expression of protein tyrosine phosphatases in normal human skin as compared to squamous cell carcinomas

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Stat3 regulates genes common to both wound healing and cancer

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based on heuristic

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STAT6 activity is regulated by SOCS-1 and modulates BCL-XL expression in primary mediastinal B-cell lymphoma.

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12 December 2020

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JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data

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deFuse: an algorithm for gene fusion discovery in tumor RNA-Seq data

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Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation

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Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma.

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12 December 2020

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Clinical, pathological and genetic features of primary mediastinal large B-cell lymphomas and mediastinal gray zone lymphomas in children

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Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

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Phosphotyrosine Signaling: Evolving a New Cellular Communication System

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12 December 2020

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Fast and SNP-tolerant detection of complex variants and splicing in short reads

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Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer

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Frequent occurrence of deletions in primary mediastinal B-cell lymphoma

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12 December 2020

based on heuristic

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Expression of protein tyrosine phosphatases and its significance in esophageal cancer

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Target sequence accessibility limits activation-induced cytidine deaminase activity in primary mediastinal B-cell lymphoma

1 reference

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reference URL

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beyond the metabolic function of PTP1B.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells

1 reference

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reference URL

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary mediastinal B-cell lymphoma treated with CHOP-like chemotherapy with or without rituximab: results of the Mabthera International Trial Group study

1 reference

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reference URL

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of specific protein tyrosine phosphatases in human breast epithelial cells neoplastically transformed by the neu oncogene.

1 reference

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PubMed

reference URL

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retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the protein tyrosine phosphatase PTP1B in human breast cancer: association with p185c-erbB-2 protein expression

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-associated macrophages and survival in classic Hodgkin's lymphoma

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance in cancer: role of ATP-dependent transporters

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Pathogenesis of Hodgkin's Lymphoma: Increasing Evidence of the Importance of the Microenvironment

1 reference

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PubMed

reference URL

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retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

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MedB-1, a human tumor cell line derived from a primary mediastinal large B-cell lymphoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24531327

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12 December 2020

based on heuristic

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Identifiers

DOI

10.1038/NG.2900

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24531327

retrieved

6 August 2017

PubMed publication ID

24531327

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24531327

retrieved

6 August 2017

 

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