Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine (Q35083525)

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English	Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 August 2017

Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

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author name string

Wei Wei

1

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Europe PubMed Central

PubMed publication ID

6 August 2017

Zhiyong Yang

2

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Europe PubMed Central

PubMed publication ID

6 August 2017

Chi-Hui Tang

3

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6 August 2017

Limin Liu

4

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6 August 2017

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publication date

8 March 2011

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Europe PubMed Central

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6 August 2017

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Europe PubMed Central

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6 August 2017

32

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6 August 2017

7

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Europe PubMed Central

PubMed publication ID

6 August 2017

973-977

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Europe PubMed Central

PubMed publication ID

6 August 2017

Lymphocyte development requires S-nitrosoglutathione reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

Endogenous S-nitrosothiols protect against myocardial injury

1 reference

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8 July 2018

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

1 reference

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Protection from experimental asthma by an endogenous bronchodilator

1 reference

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Protein S-nitrosylation: purview and parameters

1 reference

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Nitrate, bacteria and human health

1 reference

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8 July 2018

MGMT: its role in cancer aetiology and cancer therapeutics

1 reference

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8 July 2018

Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock

1 reference

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Radical causes of cancer.

1 reference

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A highly efficient recombineering-based method for generating conditional knockout mutations

1 reference

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8 July 2018

Compilation of published comparative genomic hybridization studies

1 reference

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8 July 2018

A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

Repair of O(6)-alkylguanine by alkyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

1 reference

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8 July 2018

Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

High incidence of nitrosamine-induced tumorigenesis in mice lacking DNA repair methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

Cell-specific differences in O6-alkylguanine DNA repair activity during continuous exposure to carcinogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

Immunocytochemical analysis of O6-alkylguanine shows tissue specific formation in and removal from esophageal and liver DNA in rats treated with methylbenzylnitrosamine, dimethylnitrosamine, diethylnitrosamine and ethylnitrosourea

1 reference

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8 July 2018

Elevated formation of nitrate and N-nitrosodimethylamine in woodchucks (Marmota monax) associated with chronic woodchuck hepatitis virus infection

1 reference

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8 July 2018

Nitric oxide: physiology, pathophysiology, and pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

8 July 2018

Inactivation and degradation of O(6)-alkylguanine-DNA alkyltransferase after reaction with nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

27 September 2018

Inhibition by nitric oxide of the repair protein, O6-methylguanine-DNA-methyltransferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128557

27 September 2018

Chromosomal allelic imbalance evolving from liver cirrhosis to hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR041

21 January 2018

Comprehensive allelotyping of human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR041

21 January 2018

Transgenic mice with hematopoietic and lymphoid specific expression of Cre

1 reference

https://pubmed.ncbi.nlm.nih.gov/21385828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic nitrosamine ingestion in 1040 rodents: the effect of the choice of nitrosamine, the species studied, and the age of starting exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21385828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/21385828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of formaldehyde dehydrogenase and S-formylglutathione hydrolase activities in different rat tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/21385828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/21385828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/CARCIN/BGR041

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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