APpEaLINg therapeutic target for obesity cardiomyopathy? (Q35082986)

6 August 2017

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APpEaLINg therapeutic target for obesity cardiomyopathy? (English)

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6 August 2017

Adam R Wende

1 reference

6 August 2017

Martin E Young

series ordinal

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6 August 2017

publication date

12 August 2013

1 reference

Journal of Molecular and Cellular Cardiology

6 August 2017

published in

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6 August 2017

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6 August 2017

page(s)

165-168

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Apelin and APJ, a novel critical factor and therapeutic target for atherosclerosis

6 August 2017

cites work

1 reference

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Sustained cardiovascular actions of APJ agonism during renin-angiotensin system activation and in patients with heart failure

8 July 2018

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Heart Disease and Stroke Statistics--2013 Update: A Report From the American Heart Association

8 July 2018

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Mechanisms of lipotoxicity in the cardiovascular system

8 July 2018

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Apelin and insulin resistance: another arrow for the quiver?

8 July 2018

1 reference

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Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms

8 July 2018

1 reference

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Shedding light on the enigma of myocardial lipotoxicity: the involvement of known and putative regulators of fatty acid storage and mobilization.

8 July 2018

1 reference

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Apelin is necessary for the maintenance of insulin sensitivity

8 July 2018

1 reference

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Apelin levels are increased in morbidly obese subjects with type 2 diabetes mellitus.

8 July 2018

1 reference

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Apelin stimulates glucose utilization in normal and obese insulin-resistant mice

8 July 2018

1 reference

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Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

8 July 2018

1 reference

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Adaptation and maladaptation of the heart in obesity

8 July 2018

1 reference

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Cardiac remodeling in obesity.

8 July 2018

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Endocrine functions of adipose tissue

8 July 2018

1 reference

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HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes

8 July 2018

1 reference

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Obesity cardiomyopathy: diagnosis and therapeutic implications

8 July 2018

1 reference

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Obesity cardiomyopathy: pathogenesis and pathophysiology

8 July 2018

1 reference

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Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

8 July 2018

1 reference

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Role of AMP-activated protein kinase in healthy and diseased hearts

8 July 2018

1 reference

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Adiposity of the heart, revisited

8 July 2018

1 reference

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Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms

8 July 2018

1 reference

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Myocardial insulin resistance and cardiac complications of diabetes.

8 July 2018

1 reference

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Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells

8 July 2018

1 reference

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Apelin has in vivo inotropic effects on normal and failing hearts

8 July 2018

1 reference

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

8 July 2018

1 reference

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The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

8 July 2018

1 reference

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Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

8 July 2018

1 reference

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Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor

8 July 2018

1 reference

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Apelin administration ameliorates high fat diet-induced cardiac hypertrophy and contractile dysfunction

8 July 2018

1 reference

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Apelin-13 protects the heart against ischemia-reperfusion injury through inhibition of ER-dependent apoptotic pathways in a time-dependent fashion.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327932

Effects of exogenous apelin-12 on functional and metabolic recovery of isolated rat heart after ischemia

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327932

Apelin protects heart against ischemia/reperfusion injury in rat.

27 September 2018

1 reference

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Changes and relations of circulating visfatin, apelin, and resistin levels in normal, impaired glucose tolerance, and type 2 diabetic subjects

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327932

Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327932

Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327932

Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4327932

Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.08.001

Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemiareperfusion injury

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.08.001

Hypertension in obese Zucker rats. Role of angiotensin II and adrenergic activity

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2013.08.001

10.1016/J.YJMCC.2013.08.001

7 January 2021

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference