Biosynthesis of fungal melanins and their importance for human pathogenic fungi (Q35079260)

6 August 2017

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title

Biosynthesis of fungal melanins and their importance for human pathogenic fungi (English)

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6 August 2017

Kim Langfelder

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6 August 2017

Martin Streibel

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6 August 2017

Bernhard Jahn

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6 August 2017

Gerhard Haase

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6 August 2017

Axel A Brakhage

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6 August 2017

publication date

1 March 2003

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Fungal Genetics and Biology

6 August 2017

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

143-158

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Divergent cAMP signaling pathways regulate growth and pathogenesis in the rice blast fungus Magnaporthe grisea

6 August 2017

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Signal transduction pathways regulating differentiation and pathogenicity of Cryptococcus neoformans

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Design of scytalone dehydratase inhibitors as rice blast fungicides: derivatives of norephedrine

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7 January 2021

Melanins and resistance to fungal lysis

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7 January 2021

Pigment biosynthesis and virulence

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7 January 2021

Invasive hyphal growth in Wangiella dermatitidis is induced by stab inoculation and shows dependence upon melanin biosynthesis

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7 January 2021

The isolation of tyrosinase from Aspergillus nidulans, its kinetic and molecular properties and some consideration of its activity in vivo

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7 January 2021

Localization of melanin in conidia of Alternaria alternata using phage display antibodies

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7 January 2021

Melanin and virulence in Cryptococcus neoformans

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7 January 2021

Estimation of the prevalence of cryptococcal infection among patients infected with the human immunodeficiency virus in New York City

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7 January 2021

Glycerol generates turgor in rice blast

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7 January 2021

Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans

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7 January 2021

Dynamic changes in the morphology of Cryptococcus neoformans during murine pulmonary infection

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7 January 2021

Molecular cloning and characterization of WdPKS1, a gene involved in dihydroxynaphthalene melanin biosynthesis and virulence in Wangiella (Exophiala) dermatitidis

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7 January 2021

Identification of dematiaceous fungi and their role in human disease

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7 January 2021

Enzymatic synthesis of 1,3,6,8-tetrahydroxynaphthalene solely from malonyl coenzyme A by a fungal iterative type I polyketide synthase PKS1

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7 January 2021

Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans

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7 January 2021

Molecular cloning and nucleotide sequence of the protyrosinase gene, melO, from Aspergillus oryzae and expression of the gene in yeast cells

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7 January 2021

3.2 Å structure of the copper-containing, oxygen-carrying protein Panulirus interruptus haemocyanin

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7 January 2021

Pentaketide metabolites of melanin synthesis in the dematiaceous fungus Wangiella dermatitidis

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7 January 2021

cAMP regulates morphogenesis in the fungal pathogen Ustilago maydis

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7 January 2021

Detection of melanin-like pigments in the dimorphic fungal pathogen Paracoccidioides brasiliensis in vitro and during infection

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7 January 2021

Melanins in fungal pathogens

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7 January 2021

THE DARK SIDE OF THE MYCELIUM: Melanins of Phytopathogenic Fungi

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7 January 2021

The function of melanin or six blind people examine an elephant

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7 January 2021

Molecular genetics of polyketides and its comparison to fatty acid biosynthesis

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7 January 2021

Penetration of hard substrates by a fungus employing enormous turgor pressures

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7 January 2021

Breaking and entering: host penetration by the fungal rice blast pathogen Magnaporthe grisea

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7 January 2021

Identification of two histidines as copper ligands in Streptomyces glaucescens tyrosinase

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7 January 2021

Multiple forms of protyrosinase from Aspergillus oryzae and their mode of activation at pH 3.0.

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Antioxidant function of fungal melanin

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7 January 2021

Pathogenic roles for fungal melanins

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7 January 2021

Interaction of human phagocytes with pigmentless Aspergillus conidia

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7 January 2021

Tight binding inhibitors of scytalone dehydratase: effects of site-directed mutations

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

The melanin biosynthesis genes of Alternaria alternata can restore pathogenicity of the melanin-deficient mutants of Magnaporthe grisea

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Targeted disruption of a melanin biosynthesis gene affects conidial development and UV tolerance in the Japanese pear pathotype of Alternaria alternata

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7 January 2021

Gene cluster involved in melanin biosynthesis of the filamentous fungus Alternaria alternata

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7 January 2021

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7 January 2021

DHICA oxidase activity of TRP1 and interactions with other melanogenic enzymes

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7 January 2021

Virulence and cAMP in smuts, blasts and blights

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7 January 2021

Functional analysis of the slaty gene product (TRP2) as dopachrome tautomerase and the effect of a point mutation on its catalytic function.

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7 January 2021

Identification of a polyketide synthase gene (pksP) of Aspergillus fumigatus involved in conidial pigment biosynthesis and virulence.

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7 January 2021

Differential expression of the Aspergillus fumigatus pksP gene detected in vitro and in vivo with green fluorescent protein

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7 January 2021

The pathobiology of Aspergillus fumigatus

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7 January 2021

Signal transduction cascades regulating fungal development and virulence.

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7 January 2021

Amino acid sequence of tyrosinase from Neurospora crassa

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7 January 2021

Neurospora tyrosinase: structural, spectroscopic and catalytic properties

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7 January 2021

Control of pigmentation of Ustilago hordei: the effect of pH, thiamine, and involvement of the cAMP cascade

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7 January 2021

G protein alpha subunit genes control growth, development, and pathogenicity of Magnaporthe grisea

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7 January 2021

Laccase protects Cryptococcus neoformans from antifungal activity of alveolar macrophages

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7 January 2021

Preliminary crystallographic studies on scytalone dehydratase from Magnaporthe grisea

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

1 reference

7 January 2021

The developmentally regulated Aspergillus nidulans wA gene encodes a polypeptide homologous to polyketide and fatty acid synthases

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

X-ray crystal structure of the blue oxidase ascorbate oxidase from zucchini. Analysis of the polypeptide fold and a model of the copper sites and ligands

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

The blue oxidases, ascorbate oxidase, laccase and ceruloplasmin. Modelling and structural relationships

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7 January 2021

Mechanism linking cellular pigmentation and pathogenicity in rice blast disease

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

beta-Glucosylated proteins in the cell wall of the black yeast Exophiala (Wangiella) dermatitidis

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7 January 2021

Crystallization of scytalone dehydratase F162A mutant in the unligated state and a preliminary X-ray diffraction study at 37 K

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Mechanism of the incidental production of a melanin-like pigment during 6-demethylchlortetracycline production in Streptomyces aureofaciens.

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Identification of copper ligands in Aspergillus oryzae tyrosinase by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Cryogenic X-ray crystal structure analysis for the complex of scytalone dehydratase of a rice blast fungus and its tight-binding inhibitor, carpropamid: the structural basis of tight-binding inhibition

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Melanization of Cryptococcus neoformans in murine infection

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7 January 2021

Evidence that Cryptococcus neoformans is melanized in pigeon excreta: implications for pathogenesis.

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7 January 2021

Melanisation of Cryptococcus neoformans in human brain tissue

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7 January 2021

Chemical characterization of pheomelanogenesis starting from dihydroxyphenylalanine or tyrosine and cysteine

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7 January 2021

Chemical characterization of eumelanins with special emphasis on 5,6-dihydroxyindole-2-carboxylic acid content and molecular size

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Analyses of phagocytosis, evoked oxidative burst, and killing of black yeasts by human neutrophils: a tool for estimating their pathogenicity?

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7 January 2021

Colletotrichum: A model genus for studies on pathology and fungal-plant interactions

1 reference

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7 January 2021

Histidine at the active site of Neurospora tyrosinase

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Melanin production in Aspergillus nidulans

1 reference

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7 January 2021

G proteins in Ustilago maydis: transmission of multiple signals?

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7 January 2021

Identification of genes of Aspergillus fumigatus up-regulated during growth on endothelial cells

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7 January 2021

Biosynthesis and functions of melanin in Sporothrix schenckii

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7 January 2021

Melanization decreases the susceptibility of Cryptococcus neoformans to enzymatic degradation

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7 January 2021

CJ-12,371 and CJ-12,372, two novel DNA gyrase inhibitors. Fermentation,isolation, structural elucidation and biological activities

1 reference

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7 January 2021

Effect of melanin and carotenoids of Exophiala (Wangiella) dermatitidis on phagocytosis, oxidative burst, and killing by human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Structural analysis of PKS1, a polyketide synthase gene involved in melanin biosynthesis in Colletotrichum lagenarium

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

The Alternaria alternata Melanin Biosynthesis Gene Restores Appressorial Melanization and Penetration of Cellulose Membranes in the Melanin-Deficient Albino Mutant of Colletotrichum lagenarium

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Proper regulation of cyclic AMP-dependent protein kinase is required for growth, conidiation, and appressorium function in the anthracnose fungus Colletotrichum lagenarium

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7 January 2021

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes

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7 January 2021

Signal transduction in yeast.

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7 January 2021

MAP kinase and protein kinase A-dependent mobilization of triacylglycerol and glycogen during appressorium turgor generation by Magnaporthe grisea

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

The second naphthol reductase of fungal melanin biosynthesis in Magnaporthe grisea: tetrahydroxynaphthalene reductase

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Aspergillus fumigatus arp1 modulates conidial pigmentation and complement deposition

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

A developmentally regulated gene cluster involved in conidial pigment biosynthesis in Aspergillus fumigatus.

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Pentaketide melanin biosynthesis in Aspergillus fumigatus requires chain-length shortening of a heptaketide precursor

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Novel fungal transcriptional activators, Cmr1p of Colletotrichum lagenarium and pig1p of Magnaporthe grisea, contain Cys2His2 zinc finger and Zn(II)2Cys6 binuclear cluster DNA-binding motifs and regulate transcription of melanin biosynthesis genes i

1 reference

https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Sequence and structural features of plant and fungal tyrosinases

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Polyhydroxynaphthalene reductase involved in melanin biosynthesis in Magnaporthe grisea. Purification, cDNA cloning and sequencing.

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7 January 2021

Correlation between phagocytic and membrane surface properties reflected by partitioning of human peripheral blood monocytes in two-polymer aqueous phases

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7 January 2021

Cryptococcus neoformans melanin and virulence: mechanism of action

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7 January 2021

Aspergillus fumigatus alb1 encodes naphthopyrone synthase when expressed in Aspergillus oryzae

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7 January 2021

High-resolution structures of scytalone dehydratase-inhibitor complexes crystallized at physiological pH

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

Melanin biosynthesis and the metabolism of flaviolin and 2-hydroxyjuglone in Wangiella dermatitidis.

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7 January 2021

Melanins and their importance in pathogenic fungi

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7 January 2021

Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase

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7 January 2021

Roles of substrate distortion and intramolecular hydrogen bonding in enzymatic catalysis by scytalone dehydratase

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7 January 2021

Cryptococcal disease in patients with the acquired immunodeficiency syndrome. Diagnostic features and outcome of treatment

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https://api.crossref.org/works/10.1016%2FS1087-1845%2802%2900526-1

7 January 2021

10.1016/S1087-1845(02)00526-1

Identifiers

DOI

1 reference

6 August 2017

1 reference