Phenobarbital induction of drug/steroid-metabolizing enzymes and nuclear receptor CAR. (Q35062479)

6 August 2017

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title

Phenobarbital induction of drug/steroid-metabolizing enzymes and nuclear receptor CAR. (English)

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ORCID Public Data File 2021

6 August 2017

Yukio Yamamoto

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author name string

Satoru Kakizaki

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6 August 2017

Akiko Ueda

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6 August 2017

Rick Moore

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6 August 2017

Tatsuya Sueyoshi

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6 August 2017

Masahiko Negishi

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6 August 2017

language of work or name

English

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publication date

1 February 2003

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Biochimica et Biophysica Acta

6 August 2017

published in

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6 August 2017

volume

1619

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6 August 2017

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6 August 2017

page(s)

239-242

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DRUG-INDUCED CHANGES IN THE LIVER ENDOPLASMIC RETICULUM: ASSOCIATION WITH DRUG-METABOLIZING ENZYMES

6 August 2017

cites work

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Regulatory DNA elements of phenobarbital-responsive cytochrome P450 CYP2B genes

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Activation by diverse xenochemicals of the 51-base pair phenobarbital-responsive enhancer module in the CYP2B10 gene

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7 January 2021

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

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7 January 2021

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

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7 January 2021

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

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7 January 2021

Phenobarbital response elements of cytochrome P450 genes and nuclear receptors

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7 January 2021

Regulation of cytochrome P450 (CYP) genes by nuclear receptors.

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7 January 2021

Phenobarbital-elicited activation of nuclear receptor CAR in induction of cytochrome P450 genes

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7 January 2021

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

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Molecular mechanisms of cytochrome P-450 induction by xenobiotics: An expanded role for nuclear hormone receptors.

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Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

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7 January 2021

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

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7 January 2021

Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor

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7 January 2021

A conserved nuclear receptor consensus sequence (DR-4) mediates transcriptional activation of the chicken CYP2H1 gene by phenobarbital in a hepatoma cell line.

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7 January 2021

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

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7 January 2021

Chromatin assembly enhances binding to the CYP2B1 phenobarbital-responsive unit (PBRU) of nuclear factor-1, which binds simultaneously with constitutive androstane receptor (CAR)/retinoid X receptor (RXR) and enhances CAR/RXR-mediated activation of

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7 January 2021

Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene

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7 January 2021

Characterization of phenobarbital-inducible mouse Cyp2b10 gene transcription in primary hepatocytes.

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7 January 2021

Differential Transactivation by Two Isoforms of the Orphan Nuclear Hormone Receptor CAR

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7 January 2021

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

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7 January 2021

In vivo administration of hydroxylated phenobarbital metabolites: effect on rat hepatic cytochromes P-450, epoxide hydrolase and udp-glucuronosyltransferase

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7 January 2021

10.1016/S0304-4165(02)00482-8

Identifiers

DOI

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6 August 2017

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