Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors (Q35064525)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21602825%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21602825%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21602825%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Gisela D Cymes

1 reference

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1 February 2020

language of work or name

English

0 references

publication date

22 May 2011

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1 February 2020

1 reference

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1 February 2020

volume

474

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1 February 2020

issue

7352

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1 February 2020

page(s)

526-530

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Structural origins of high apparent dielectric constants experienced by ionizable groups in the hydrophobic core of a protein

1 February 2020

cites work

1 reference

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Conformational consequences of ionization of Lys, Asp, and Glu buried at position 66 in staphylococcal nuclease

8 July 2018

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The pKa Values of Acidic and Basic Residues Buried at the Same Internal Location in a Protein Are Governed by Different Factors

8 July 2018

1 reference

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Progress in ab initio QM/MM free-energy simulations of electrostatic energies in proteins: accelerated QM/MM studies of pKa, redox reactions and solvation free energies

8 July 2018

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Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer

8 July 2018

1 reference

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A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family

8 July 2018

1 reference

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Desensitization contributes to the synaptic response of gain-of-function mutants of the muscle nicotinic receptor

8 July 2018

1 reference

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Probing ion-channel pores one proton at a time

8 July 2018

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Ligand-gated ion channels: mechanisms underlying ion selectivity

8 July 2018

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Restoration of single-channel currents using the segmental k-means method based on hidden Markov modeling

8 July 2018

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EXP-1 is an excitatory GABA-gated cation channel

8 July 2018

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A single ring of charged amino acids at one end of the pore can control ion selectivity in the 5-HT3 receptor

8 July 2018

1 reference

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Mutations at the GABA receptor selectivity filter: a possible role for effective charges

8 July 2018

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Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity

8 July 2018

1 reference

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What are the dielectric "constants" of proteins and how to validate electrostatic models?

8 July 2018

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M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121909

Asymmetric and independent contribution of the second transmembrane segment 12' residues to diliganded gating of acetylcholine receptor channels: a single-channel study with choline as the agonist

8 July 2018

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New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome

8 July 2018

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Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121909

Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans

8 July 2018

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Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit

8 July 2018

1 reference

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Liquid junction potentials and small cell effects in patch-clamp analysis

8 July 2018

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Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic

8 July 2018

1 reference

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Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10015

The beta subunit determines the ion selectivity of the GABAA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10015

Chimeric mutations in the M2 segment of the 5-hydroxytryptamine-gated chloride channel MOD-1 define a minimal determinant of anion/cation permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10015

Identification of molluscan nicotinic acetylcholine receptor (nAChR) subunits involved in formation of cation- and anion-selective nAChRs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10015

The contribution of proline 250 (P-2') to pore diameter and ion selectivity in the human glycine receptor channel

21 January 2018

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Homomeric beta 1 gamma-aminobutyric acid A receptor-ion channels: evaluation of pharmacological and physiological properties.

21 January 2018

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Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Desensitization of neurotransmitter-gated ion channels during high-frequency stimulation: a comparative study of Cys-loop, AMPA and purinergic receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanism of Cl- selection by a glutamate-gated chloride (GluCl) receptor revealed through mutations in the selectivity filter

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21602825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE10015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21602825%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 February 2020

0 references

1 reference

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1 February 2020

PubMed publication ID

21602825

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21602825%20AND%20SRC:MED&resulttype=core&format=json