Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals (Q35064369)

6 August 2017

title

Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals (English)

1 reference

6 August 2017

Andrew E. Greenstein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21646519

3 December 2024

Margaret Robinson

1 reference

6 August 2017

Yang Tian

series ordinal

1 reference

6 August 2017

William E. Delaney

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21646519

3 December 2024

language of work or name

English

0 references

publication date

6 June 2011

1 reference

full work available at URL

6 August 2017

https://europepmc.org/articles/pmc3121856?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21646519

https://europepmc.org/articles/PMC3121856

3 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21646519

https://europepmc.org/articles/PMC3121856?pdf=render

3 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21646519

https://doi.org/10.1073/pnas.1101515108

3 December 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21646519

https://pnas.org/doi/pdf/10.1073/pnas.1101515108

3 December 2024

1 reference

DOI

10.1073/PNAS.1101515108

https://api.crossref.org/works/10.1073/PNAS.1101515108

Proceedings of the National Academy of Sciences of the United States of America

3 December 2024

published in

1 reference

6 August 2017

volume

108

1 reference

6 August 2017

1 reference

6 August 2017

page(s)

10290-10295

1 reference

A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach

6 August 2017

cites work

1 reference

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Tracking the evolution of multiple in vitro hepatitis C virus replicon variants under protease inhibitor selection pressure by 454 deep sequencing

8 July 2018

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Novel hepatitis C virus reporter replicon cell lines enable efficient antiviral screening against genotype 1a

8 July 2018

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Estimation of inhibitory quotient using a comparative equilibrium dialysis assay for prediction of viral response to hepatitis C virus inhibitors

8 July 2018

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Rapid emergence of protease inhibitor resistance in hepatitis C virus

8 July 2018

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Mechanism of resistance of hepatitis C virus replicons to structurally distinct cyclophilin inhibitors

8 July 2018

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Resistance to direct antiviral agents in patients with hepatitis C virus infection

8 July 2018

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MK-7009, a Potent and Selective Inhibitor of Hepatitis C Virus NS3/4A Protease

8 July 2018

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Screening for hepatitis C virus non-nucleotide resistance mutations in treatment-naive women

8 July 2018

1 reference

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Mutations in the hepatitis C virus polymerase that increase RNA binding can confer resistance to cyclosporine A

8 July 2018

1 reference

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GT-1a or GT-1b Subtype-Specific Resistance Profiles for Hepatitis C Virus Inhibitors Telaprevir and HCV-796

8 July 2018

1 reference

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Molecular Mechanism of Hepatitis C Virus Replicon Variants with Reduced Susceptibility to a Benzofuran Inhibitor, HCV-796

8 July 2018

1 reference

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Relative Replication Capacity and Selective Advantage Profiles of Protease Inhibitor-Resistant Hepatitis C Virus (HCV) NS3 Protease Mutants in the HCV Genotype 1b Replicon System

8 July 2018

1 reference

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Characterization of Hepatitis C Virus Subgenomic Replicon Resistance to Cyclosporine In Vitro

8 July 2018

1 reference

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Evolution of Resistant M414T Mutants among Hepatitis C Virus Replicon Cells Treated with Polymerase Inhibitor A-782759

8 July 2018

1 reference

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Mutations of Bacteria from Virus Sensitivity to Virus Resistance

8 July 2018

1 reference

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Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro

8 July 2018

1 reference

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Complete replication of hepatitis C virus in cell culture

8 July 2018

1 reference

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Replication fitness and NS5B drug sensitivity of diverse hepatitis C virus isolates characterized by using a transient replication assay

8 July 2018

1 reference

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Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes

8 July 2018

1 reference

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Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro

8 July 2018

1 reference

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Dynamics of Subgenomic Hepatitis C Virus Replicon RNA Levels in Huh-7 Cells after Exposure to Nucleoside Antimetabolites

8 July 2018

1 reference

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Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro

8 July 2018

1 reference

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

8 July 2018

1 reference

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Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

8 July 2018

1 reference

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Characterization of resistance mutations against HCV ketoamide protease inhibitors

8 July 2018

1 reference

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Telaprevir and pegylated interferon-alpha-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients

21 January 2018

1 reference

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Antiviral effects and safety of telaprevir, peginterferon alfa-2a, and ribavirin for 28 days in hepatitis C patients

21 January 2018

1 reference

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Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir

21 January 2018

1 reference

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The emerging field of HCV drug resistance

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21646519

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1101515108

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference