Targeting monocyte chemoattractant protein-1 signalling in disease (Q35056023)

6 August 2017

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title

Targeting monocyte chemoattractant protein-1 signalling in disease (English)

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6 August 2017

Janet Dawson

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Wolfgang Miltz

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6 August 2017

Anis K Mir

series ordinal

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6 August 2017

Christoph Wiessner

series ordinal

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6 August 2017

language of work or name

English

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publication date

1 February 2003

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Expert Opinion on Therapeutic Targets

6 August 2017

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

35-48

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6 August 2017

cites work

Chemokines and disease

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The biology of chemokines and their receptors

21 January 2018

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Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2

21 January 2018

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Defects in Macrophage Recruitment and Host Defense in Mice Lacking the CCR2 Chemokine Receptor

21 January 2018

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Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice

21 January 2018

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Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice

21 January 2018

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The chemokine system: redundancy for robust outputs

21 January 2018

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Chemokines as regulators of T cell differentiation.

21 January 2018

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Chemokines--chemotactic cytokines that mediate inflammation

21 January 2018

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Leukocyte polarization in cell migration and immune interactions

21 January 2018

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Opportunities for novel therapeutic agents acting at chemokine receptors

21 January 2018

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Dancing to the tune of chemokines

21 January 2018

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Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

21 January 2018

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Enhanced production of CC-chemokines (RANTES, MCP-1, MIP-1alpha, MIP-1beta, and eotaxin) in patients with atopic dermatitis

21 January 2018

1 reference

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MCP-1 induces inflammatory activation of human tubular epithelial cells: involvement of the transcription factors, nuclear factor-kappaB and activating protein-1.

21 January 2018

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The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness

21 January 2018

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Comparative effect of danazol and a GnRH agonist on monocyte chemotactic protein-1 expression by endometriotic cells

21 January 2018

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Monocyte chemoattractant protein-1 in human atheromatous plaques

21 January 2018

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Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions

21 January 2018

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Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis

21 January 2018

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Chemokines control fat accumulation and leptin secretion by cultured human adipocytes

21 January 2018

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Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease

21 January 2018

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Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis

21 January 2018

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Treatment with sulfasalazine or sulfapyridine, but not 5-aminosalicyclic acid, inhibits basic fibroblast growth factor-induced endothelial cell chemotaxis

21 January 2018

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An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model

21 January 2018

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C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis

21 January 2018

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Amelioration of rat adjuvant arthritis by therapeutic treatment with bindarit, an inhibitor of MCP-1 and TNF-alpha production

21 January 2018

1 reference

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Chemokine expression by subchondral bone marrow stromal cells isolated from osteoarthritis (OA) and rheumatoid arthritis (RA) patients.

21 January 2018

1 reference

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Regulation of chemokine gene expression in human endothelial cells by proinflammatory cytokines and Borrelia burgdorferi.

21 January 2018

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Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain

21 January 2018

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21 January 2018

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Chemokines CXCL10 and CCL2: differential involvement in intrathecal inflammation in multiple sclerosis.

21 January 2018

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CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis

21 January 2018

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Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2.

21 January 2018

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Anti-inflammatory drugs in the fight against Alzheimer's disease

21 January 2018

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Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

21 January 2018

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Early association of reactive astrocytes with senile plaques in Alzheimer's disease

21 January 2018

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Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Identification of monocyte chemoattractant protein‐1 in senile plaques and reactive microglia of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Monocyte chemoattractant protein-1 expressed in neurons and astrocytes during focal ischemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Neuronal MCP-1 expression in response to remote nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Molecular profile of reactive astrocytes--implications for their role in neurologic disease

21 January 2018

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Microglia: a sensor for pathological events in the CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Monocyte chemoattractant protein-1 is increased in the cerebrospinal fluid of patients with ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Monocyte chemoattractant protein-1 is a mediator of acute excitotoxic injury in neonatal rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Monocyte chemoattractant protein-1 deficiency is protective in a murine stroke model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Interleukin 1 in the brain: biology, pathology and therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Chemokine receptor antagonist peptide, viral MIP-II, protects the brain against focal cerebral ischemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Inflammatory mediators and stroke: new opportunities for novel therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Ischemic cerebral tissue and MCP-1 enhance rat bone marrow stromal cell migration in interface culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Chemokine inhibition in rat stab wound brain injury using antisense oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Expression of monocyte chemoattractant protein (MCP-1) and nitric oxide synthase-2 following cerebral trauma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Ablation of the chemokine monocyte chemoattractant protein-1 delays retrograde neuronal degeneration, attenuates microglial activation, and alters expression of cell death molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Acute spinal cord injury, part II: contemporary pharmacotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Chemokine antagonist infusion promotes axonal sparing after spinal cord contusion injury in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

The role of CC chemokine receptor 2 in alveolar monocyte and neutrophil immigration in intact mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Angiotensin AT1 receptor antagonist irbesartan decreases lesion size, chemokine expression, and macrophage accumulation in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

CCR2B receptor antagonists: conversion of a weak HTS hit to a potent lead compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

Conformationally restricted indolopiperidine derivatives as potent CCR2B receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.35

21 January 2018

Identifiers

DOI

10.1517/14728222.7.1.35

1 reference

6 August 2017

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