Loss of a single Hic1 allele accelerates polyp formation in Apc(Δ716) mice (Q35042805)

6 August 2017

title

Loss of a single Hic1 allele accelerates polyp formation in Apc(Δ716) mice (English)

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6 August 2017

H P Mohammad

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6 August 2017

W Zhang

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6 August 2017

H S Prevas

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6 August 2017

B R Leadem

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6 August 2017

M Zhang

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6 August 2017

J G Herman

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6 August 2017

C M Hooker

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6 August 2017

D N Watkins

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6 August 2017

B Karim

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6 August 2017

D L Huso

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6 August 2017

S B Baylin

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6 August 2017

language of work or name

English

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publication date

7 February 2011

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6 August 2017

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

2659-2669

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SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling

6 August 2017

cites work

1 reference

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8 July 2018

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Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1).

8 July 2018

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8 July 2018

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SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol

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8 July 2018

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Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma

8 July 2018

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8 July 2018

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Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

8 July 2018

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HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies

8 July 2018

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Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation

8 July 2018

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Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state

8 July 2018

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Short telomeres, even in the presence of telomerase, limit tissue renewal capacity

8 July 2018

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Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

8 July 2018

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Wnt signaling in the intestinal epithelium: from endoderm to cancer

8 July 2018

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Wnt signalling in stem cells and cancer

8 July 2018

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Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

8 July 2018

1 reference

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SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

8 July 2018

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The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties

8 July 2018

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8 July 2018

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The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif

8 July 2018

1 reference

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Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114184

8 July 2018

Wnt signaling and cancer

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Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: the case of HIC-1 and gammaFBP-B

8 July 2018

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The carboxy-terminal end of the candidate tumor suppressor gene HIC-1 is phylogenetically conserved

8 July 2018

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Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer

8 July 2018

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Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114184

p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

8 July 2018

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A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

8 July 2018

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A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

8 July 2018

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Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114184

Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome.

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.633

Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.633

Analysis of SOX9 expression in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.633

Heterogeneity of DNA methylation status analyzed by bisulfite-PCR-SSCP and correlation with clinico-pathological characteristics in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.633

Derivation of mouse intestinal crypts from single progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.633

Proliferative index in breast carcinoma determined in situ by Ki67 immunostaining and its relationship to clinical and pathological variables

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.633

Protein kinase C alpha but not PKCzeta suppresses intestinal tumor formation in ApcMin/+ mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.633

Involvement of OX40-OX40L interactions in the intestinal manifestations of the murine acute graft-versus-host disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.633

Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21297660

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2010.633

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference