Evaluation of OspA vaccination-induced serological correlates of protection against Lyme borreliosis in a mouse model (Q35048164)

6 August 2017

title

Evaluation of OspA vaccination-induced serological correlates of protection against Lyme borreliosis in a mouse model (English)

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6 August 2017

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Andreas Traweger

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Helga Savidis-Dacho

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6 August 2017

P Noel Barrett

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6 August 2017

author name string

Michael G Schwendinger

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6 August 2017

Maria O'Rourke

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6 August 2017

Andreas Pilz

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6 August 2017

Daniel Portsmouth

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6 August 2017

Ian Livey

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6 August 2017

Brian A Crowe

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6 August 2017

language of work or name

English

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publication date

18 November 2013

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6 August 2017

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

e79022

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Creative Commons Attribution 3.0 Unported

6 August 2017

start time

18 November 2013

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Relationship between Immunity to Borrelia burgdorferi Outer-surface Protein A (OspA) and Lyme Arthritis

8 July 2018

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Vaccines against Lyme Disease: What Happened and What Lessons Can We Learn?

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Correlates of protection induced by vaccination

8 July 2018

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Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector

8 July 2018

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Tick–host–pathogen interactions in Lyme borreliosis

8 July 2018

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8 July 2018

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Safety and immunogenicity of a recombinant Borrelia burgdorferi outer surface protein A vaccine against lyme disease in healthy children and adolescents: a randomized controlled trial

8 July 2018

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Growth-inhibiting antibody responses of humans vaccinated with recombinant outer surface protein A or infected with Borrelia burgdorferi or both.

8 July 2018

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Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. Lyme Disease Vaccine Study Group

8 July 2018

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Vaccination of natural reservoir hosts with recombinant lipidated OspA induces a transmission-blocking immunity against Lyme disease spirochaetes associated with high levels of LA-2 equivalent antibodies

8 July 2018

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Plasminogen Is Required for Efficient Dissemination of B. burgdorferi in Ticks and for Enhancement of Spirochetemia in Mice

8 July 2018

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Reactivity with a specific epitope of outer surface protein A predicts protection from infection with the Lyme disease spirochete, Borrelia burgdorferi

8 July 2018

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Detection of anti-Borrelia burgdorferi antibody responses with the borreliacidal antibody test, indirect fluorescent-antibody assay performed by flow cytometry, and western immunoblotting

8 July 2018

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Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kilodalton antigen

8 July 2018

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8 July 2018

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The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor

8 July 2018

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Abilities of OspA proteins from different seroprotective groups of Borrelia burgdorferi to protect hamsters from infection.

8 July 2018

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Growth inhibition of Borrelia burgdorferi sensu lato by antibodies. A contribution to understanding the pathogenesis and improving diagnosis of Lyme borreliosis

8 July 2018

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Differentiation of borreliacidal activity caused by immune serum or antimicrobial agents by flow cytometry

8 July 2018

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A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. Recombinant Outer-Surface Protein A Lyme Disease Vaccine Study Consortium

8 July 2018

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Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis

21 January 2018

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Correcting a Public Health Fiasco: The Need for a New Vaccine against Lyme Disease

21 January 2018

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Safety and immunogenicity profile of a recombinant outer-surface protein A Lyme disease vaccine: clinical trial of a 3-dose schedule at 0, 1, and 2 months.

21 January 2018

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In Vitro Inhibition of Borrelia burgdorferi Growth by Antibodies

21 January 2018

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Immunization with a polyvalent OspA vaccine protects mice against Ixodes ricinus tick bites infected by Borrelia burgdorferi ss, Borrelia garinii and Borrelia afzelii

21 January 2018

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12 December 2020

A new approach to a Lyme disease vaccine

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12 December 2020

Immunogenicity of a recombinant Borrelia burgdorferi outer surface protein A vaccine against Lyme disease in children

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12 December 2020

Inhibition of Borrelia burgdorferi-tick interactions in vivo by outer surface protein A antibody

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12 December 2020

An open-label, nonrandomized, single-center, prospective extension, clinical trial of booster dose schedules to assess the safety profile and immunogenicity of recombinant outer-surface protein A (OspA) Lyme disease vaccine

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12 December 2020

Characterization of Borrelia burgdorferi isolated from different organs of Ixodes ricinus ticks collected in nature

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12 December 2020

The Lyme disease vaccine candidate outer surface protein A (OspA) in a formulation compatible with human use protects mice against natural tick transmission of B. burgdorferi

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12 December 2020

Incomplete protection of hamsters vaccinated with unlipidated OspA from Borrelia burgdorferi infection is associated with low levels of antibody to an epitope defined by mAb LA-2

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12 December 2020

10.1371/JOURNAL.PONE.0079022

Identifiers

DOI

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6 August 2017

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6 August 2017

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