Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia (Q35046100)

6 August 2017

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title

Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia (English)

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6 August 2017

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lymphoblastic leukemia

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Tissing WJ

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6 August 2017

Meijerink JP

series ordinal

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6 August 2017

den Boer ML

series ordinal

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6 August 2017

Pieters R

series ordinal

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6 August 2017

language of work or name

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1 January 2003

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6 August 2017

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

17-25

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[Corticosteroid-dependent reduction of leukocyte count in blood as a prognostic factor in acute lymphoblastic leukemia in childhood (therapy study ALL-BFM 83)]

6 August 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Good steroid response in vivo predicts a favorable outcome in children with T-cell acute lymphoblastic leukemia. The Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP)

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7 January 2021

Relation of cellular drug resistance to long-term clinical outcome in childhood acute lymphoblastic leukaemia

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7 January 2021

Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia--implications for treatment of infants

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7 January 2021

Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Regional chromosomal assignment of the human glucocorticoid receptor gene to 5q31

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Mapping of glucocorticoid receptor DNA binding domain surfaces contributing to transrepression of NF-kappa B and induction of apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Anti-inflammatory actions of glucocorticoids: molecular mechanisms

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Role of molecular chaperones in subnuclear trafficking of glucocorticoid receptors

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Gene regulation by steroid hormones

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Novel antipeptide antibodies to the human glucocorticoid receptor: recognition of multiple receptor forms in vitro and distinct localization of cytoplasmic and nuclear receptors

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

DNA binding of the glucocorticoid receptor is not essential for survival

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Autoregulation of glucocorticoid receptor gene expression

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Downregulation of the glucocorticoid receptor. A mechanism for physiological adaptation to hormones.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Differences in down-regulation of glucocorticoid receptor mRNA by cortisol, prednisolone and dexamethasone in HeLa cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Effect of glucocorticoid therapy on glucocorticoid receptors in children with autoimmune diseases

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Regulation of the human glucocorticoid receptor by long-term and chronic treatment with glucocorticoid

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Expression of the human glucocorticoid receptor alpha and beta isoforms in human respiratory epithelial cells and their regulation by dexamethasone.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Plasma membrane-resident glucocorticoid receptors in rodent lymphoma and human leukemia models

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

A mutation of the glucocorticoid receptor in primary cortisol resistance

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Characterization of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Five missense variants in the amino-terminal domain of the glucocorticoid receptor: no association with puerperal psychosis or schizophrenia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

High penetrance, overweight, and glucocorticoid receptor variant: case-control study

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Primary structure and expression of a functional human glucocorticoid receptor cDNA

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Immunocytochemical analysis of the glucocorticoid receptor alpha isoform (GRalpha) using GRalpha-specific antibody.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Low glucocorticoid receptor alpha/beta ratio in T-cell lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Receptor binding cancer antigen expressed on SiSo cells, a novel regulator of apoptosis of erythroid progenitor cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

The human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative function

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Expression and subcellular distribution of the beta-isoform of the human glucocorticoid receptor

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Evidence That the β-Isoform of the Human Glucocorticoid Receptor Does Not Act as a Physiologically Significant Repressor

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Glucocorticoid Receptor beta: View II

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Glucocorticoid Receptor beta: View I

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Association of Glucocorticoid Insensitivity with Increased Expression of Glucocorticoid Receptor β

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Glucocorticoid receptor alpha and beta in glucocorticoid dependent asthma

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Natural variants of the beta isoform of the human glucocorticoid receptor do not alter sensitivity to glucocorticoids

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Interaction of glucocorticoid receptor isoforms with transcription factors AP-1 and NF-kappaB: lack of effect of glucocorticoid receptor beta.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Glucocorticoid receptor phosphorylation: overview, function and cell cycle-dependence.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Constitutive expression levels of CD95 and Bcl-2 as well as CD95 function and spontaneous apoptosis in vitro do not predict the response to induction chemotherapy and relapse rate in childhood acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Raised blast glutathione levels are associated with an increased risk of relapse in childhood acute lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Different expression of glutathione S-transferase alpha, mu and pi in childhood acute lymphoblastic and myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Polymorphisms within glutathione S-transferase genes and initial response to glucocorticoids in childhood acute lymphoblastic leukaemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

The molecular chaperones Hsp90 and Hsc70 are both necessary and sufficient to activate hormone binding by glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

RAP46 is a negative regulator of glucocorticoid receptor action and hormone-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Glucocorticoid-induced apoptosis and regulation of NF-kappaB activity in human leukemic T cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

The role of AP-1 in glucocorticoid resistance in leukaemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Glucocorticoids, oxysterols, and cAMP with glucocorticoids each cause apoptosis of CEM cells and suppress c-myc

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Constitutive expression of ectopic c-Myc delays glucocorticoid-evoked apoptosis of human leukemic CEM-C7 cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Involvement of c-myc in the resistance of non-obese diabetic mice to glucocorticoid-induced apoptosis.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

c-Myc does not prevent glucocorticoid-induced apoptosis of human leukemic lymphoblasts

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Expression profiling of glucocorticoid-treated T-ALL cell lines: rapid repression of multiple genes involved in RNA-, protein- and nucleotide synthesis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Delineation of the signaling pathways involved in glucocorticoid-induced and spontaneous apoptosis of rat thymocytes

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Death receptors: signaling and modulation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Bcl-2 interferes with the execution phase, but not upstream events, in glucocorticoid-induced leukemia apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Bcl-2 family members in childhood acute lymphoblastic leukemia: relationships with features at presentation, in vitro and in vivo drug response and long-term clinical outcome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

BCL-2 expression in childhood leukemia versus spontaneous apoptosis, drug induced apoptosis, and in vitro drug resistance

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402733

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402733

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Dimensions Publication ID

6 August 2017

1018838242

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