Tyrosine kinases as targets for cancer therapy (Q35045444)

6 August 2017

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title

Tyrosine kinases as targets for cancer therapy. (English)

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6 August 2017

Alexander Levitzki

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6 August 2017

publication date

1 September 2002

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European Journal of Cancer

6 August 2017

published in

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6 August 2017

volume

38 Suppl 5

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6 August 2017

page(s)

S11-8

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Tyrphostins--potential antiproliferative agents and novel molecular tools

6 August 2017

cites work

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Signal-transduction therapy. A novel approach to disease management

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Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors

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Phosphorylation site-specific inhibition of platelet-derived growth factor beta-receptor autophosphorylation by the receptor blocking tyrphostin AG1296.

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7 January 2021

Epidermal growth factor receptor tyrosine kinase. Investigation of catalytic mechanism, structure-based searching and discovery of a potent inhibitor

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Dianilinophthalimides: potent and selective, ATP-competitive inhibitors of the EGF-receptor protein tyrosine kinase

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A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

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Tyrphostins IV--highly potent inhibitors of EGF receptor kinase. Structure-activity relationship study of 4-anilidoquinazolines

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Tyrphostins. 5. Potent inhibitors of platelet-derived growth factor receptor tyrosine kinase: structure-activity relationships in quinoxalines, quinolines, and indole tyrphostins

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Substrate competitive inhibitors of IGF-1 receptor kinase

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Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

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EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling

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ROS, stress-activated kinases and stress signaling in cancer

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Tyrosine kinase inhibition: an approach to drug development

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

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Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

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Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

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Drug development train gathering steam

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Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

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Studies on a new epidermal growth factor-receptor kinase inhibitor, erbstatin, produced by MH435-hF3

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7 January 2021

Tyrphostins. II. Heterocyclic and .alpha.-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases

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7 January 2021

Tyrphostins. 3. Structure-activity relationship studies of alpha-substituted benzylidenemalononitrile 5-S-aryltyrphostins

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7 January 2021

Protein tyrosine kinase inhibitors as novel therapeutic agents

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7 January 2021

Focal adhesion kinase (FAK) phosphorylation is not required for genistein-induced FAK-beta-1-integrin complex formation.

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7 January 2021

The inhibition of EGF-dependent proliferation of keratinocytes by tyrphostin tyrosine kinase blockers

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Tyrphostins suppress the growth of psoriatic keratinocytes

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7 January 2021

Growth inhibition of psoriatic keratinocytes by quinazoline tyrosine kinase inhibitors

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7 January 2021

PDGF-receptor tyrosine kinase blocker AG1295 selectively attenuates smooth muscle cell growth in vitro and reduces neointimal formation after balloon angioplasty in swine

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7 January 2021

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Identifiers

DOI

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6 August 2017

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