Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling (Q35032890)

5 August 2017

title

Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling (English)

1 reference

5 August 2017

1 reference

Yong Pan

1 reference

5 August 2017

Elizabeth A Schroeder

1 reference

5 August 2017

Alejandro Ocampo

1 reference

5 August 2017

Antoni Barrientos

1 reference

5 August 2017

Gerald S Shadel

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5 August 2017

publication date

1 June 2011

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

668-678

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Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence

5 August 2017

cites work

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Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

8 July 2018

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Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension

8 July 2018

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Gis1 is required for transcriptional reprogramming of carbon metabolism and the stress response during transition into stationary phase in yeast

8 July 2018

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Caffeine extends yeast lifespan by targeting TORC1.

8 July 2018

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Increased respiration in the sch9Delta mutant is required for increasing chronological life span but not replicative life span

8 July 2018

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Expression and maintenance of mitochondrial DNA: new insights into human disease pathology

8 July 2018

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8 July 2018

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Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9

8 July 2018

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Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

8 July 2018

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Rethinking the mitochondrial theory of aging: the role of mitochondrial gene expression in lifespan determination

8 July 2018

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Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

8 July 2018

1 reference

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Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression

8 July 2018

1 reference

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The essential requirement for superoxide radical and nitric oxide formation for normal physiological function and healthy aging

8 July 2018

1 reference

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The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

8 July 2018

1 reference

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Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span

8 July 2018

1 reference

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TOR signaling in growth and metabolism

8 July 2018

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Extension of chronological life span in yeast by decreased TOR pathway signaling

8 July 2018

1 reference

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Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

8 July 2018

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Sir2 blocks extreme life-span extension.

8 July 2018

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A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

8 July 2018

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Molecular organization of target of rapamycin complex 2.

8 July 2018

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Mitochondria, oxidants, and aging

8 July 2018

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Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae.

8 July 2018

1 reference

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Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

8 July 2018

1 reference

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TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae

8 July 2018

1 reference

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Genetics: influence of TOR kinase on lifespan in C. elegans

8 July 2018

1 reference

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SOD2 functions downstream of Sch9 to extend longevity in yeast

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Exposure of yeast cells to anoxia induces transient oxidative stress. Implications for the induction of hypoxic genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Mitochondrial reactive oxygen species in cell death signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Regulation of longevity and stress resistance by Sch9 in yeast

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Mitochondrial superoxide decreases yeast survival in stationary phase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Getting started with yeast

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Suppression of polyglutamine-induced cytotoxicity in Saccharomyces cerevisiae by enhancement of mitochondrial biogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

C. elegans longevity pathways converge to decrease mitochondrial membrane potential.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Mitochondrial dysfunction leads to reduced chronological lifespan and increased apoptosis in yeast

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

The chronological life span of Saccharomyces cerevisiae to study mitochondrial dysfunction and disease.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Preadaptation to efficient respiratory maintenance is essential both for maximal longevity and the retention of replicative potential in chronologically ageing yeast.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Caloric restriction augments ROS defense in S. cerevisiae, by a Sir2p independent mechanism.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

The novel yeast PAS kinase Rim 15 orchestrates G0-associated antioxidant defense mechanisms

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Rates of behavior and aging specified by mitochondrial function during development

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

Mitochondria-targeted green fluorescent proteins: convenient tools for the study of organelle biogenesis in Saccharomyces cerevisiae

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3110654

The chronological life span of Saccharomyces cerevisiae

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21641548

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2011.03.018

1 reference

5 August 2017

1 reference

5 August 2017

1 reference