Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance (Q35027940)

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English	Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

Europe PubMed Central

Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

based on heuristic

inferred from title

drug resistance

1 reference

based on heuristic

inferred from title

author name string

Danny Burg

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Gerard J Mulder

2

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

language of work or name

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publication date

1 November 2002

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Drug Metabolism Reviews

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

34

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

821-863

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Glutathione synthesis is essential for mouse development but not for cell growth in culture

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The gamma-glutamyl cycle: a possible transport system for amino acids

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Novel roles for glutathione in gene expression, cell death, and membrane transport of organic solutes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Detoxification of 1-chloro-2,4-dinitrobenzene in MCF7 breast cancer cells expressing glutathione S-transferase P1-1 and/or multidrug resistance protein 1.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Coordinated action of glutathione S-transferases (GSTs) and multidrug resistance protein 1 (MRP1) in antineoplastic drug detoxification. Mechanism of GST A1-1- and MRP1-associated resistance to chlorambucil in MCF7 breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cells.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Role of multidrug resistance protein 1 (MRP1) and glutathione S-transferase A1-1 in alkylating agent resistance. Kinetics of glutathione conjugate formation and efflux govern differential cellular sensitivity to chlorambucil versus melphalan toxicit

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Chemoprotective functions of glutathione S-transferases in cell lines induced to express specific isozymes by stable transfection

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Coordinate changes in expression of protective genes in drug-resistant cells

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Induction of multidrug resistance proteins MRP1 and MRP3 and gamma-glutamylcysteine synthetase gene expression by nonsteroidal anti-inflammatory drugs in human colon cancer cells

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The glutathione-related detoxification pathway in the human breast: a highly coordinated system disrupted in the tumour tissues.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Cellular mechanisms of resistance to chronic oxidative stress

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Leukotriene C4 synthase. A pivotal enzyme in the biosynthesis of the cysteinyl leukotrienes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The redox pathway of S-nitrosoglutathione, glutathione and nitric oxide in cell to neuron communications

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Design and synthesis of glutathione analogues

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The glutathione-binding site in glutathione S-transferases. Investigation of the cysteinyl, glycyl and gamma-glutamyl domains

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Isozyme-specific glutathione-S-transferase inhibitors: design and synthesis

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Isozyme specificity of novel glutathione-S-transferase inhibitors.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Inhibition of glutathione conjugation in the rat in vivo by analogues of glutathione conjugates

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

S-(N-aryl-N-hydroxycarbamoyl)glutathione derivatives are tight-binding inhibitors of glyoxalase I and slow substrates for glyoxalase II.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Structure-activity study on the in vitro antiprotozoal activity of glutathione derivatives

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

QSAR study on the contribution of log P and E(s) to the in vitro antiprotozoal activity of glutathione derivatives

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Transport of glutathione diethyl ester into human cells

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Phosphono analogs of glutathione: inhibition of glutathione transferases, metabolic stability, and uptake by cancer cells.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Synthesis and glutathione S-transferase structure-affinity relationships of nonpeptide and peptidase-stable glutathione analogues

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Identification, characterization, and crystal structure of the Omega class glutathione transferases

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Zeta, a novel class of glutathione transferases in a range of species from plants to humans

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Heterodimers of glutathione S-transferase can form between isoenzyme classes pi and mu.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Development of a peptide antibody specific to human glutathione S-transferase alpha 4-4 (hGSTA4-4) reveals preferential localization in human liver mitochondria

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Immunohistochemical localization of glutathione S-transferase-T1 in murine kidney, liver, and lung

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Mammalian class theta GST and differential susceptibility to carcinogens: a review

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Immunohistochemical demonstration of epithelial glutathione S-transferase isoenzymes in normal, benign, premalignant and malignant human oral mucosa.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Doxorubicin-induced DNA intercalation and scavenging by nuclear glutathione S-transferase pi.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Structure, catalytic mechanism, and evolution of the glutathione transferases

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Studies of the relationship between the catalytic activity and binding of non-substrate ligands by the glutathione S-transferases

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Intracellular binding and transport of hormones and xenobiotics by glutathione-S-transferases

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site)

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Human glutathione transferase P1-1 and nitric oxide carriers; a new role for an old enzyme

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Regulation of JNK signaling by GSTp

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs).

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Hypochlorous acid is a potent inhibitor of GST P1-1.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

A novel plant glutathione S-transferase/peroxidase suppresses Bax lethality in yeast.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione transferases and cancer

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Antineoplastic drug resistance and breast cancer

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

A proof of glutathione S-transferase-pi-related multidrug resistance by transfer of antisense gene to cancer cells and sense gene to bone marrow stem cell

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Suppression of GST-P by treatment with glutathione-doxorubicin conjugate induces potent apoptosis in rat hepatoma cells

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Lack of glutathione conjugation to adriamycin in human breast cancer MCF-7/DOX cells. Inhibition of glutathione S-transferase p1-1 by glutathione conjugates from anthracyclines

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Free radicals and anticancer drug resistance: oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Inhibition of human term placental and fetal liver glutathione-S-transferases by fatty acids and fatty acid esters

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

alpha-Tocopherol inhibits human glutathione S-transferase pi.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Inhibition of human glutathione S-transferase P1-1 by tocopherols and alpha-tocopherol derivatives

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione analogues as novel inhibitors of rat and human glutathione S-transferase isoenzymes, as well as of glutathione conjugation in isolated rat hepatocytes and in the rat in vivo

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Ligand-based protein alignment and isozyme specificity of glutathione S-transferase inhibitors

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Weak electrophile selective characteristics of the rat preneoplastic marker enzyme glutathione S-transferase P-form, GST-P (7-7): a theory of linear free energy relationships for evaluation of the active site hydrophobicity of isoenzymes.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Involvement of DNA-dependent protein kinase in regulation of stress-induced JNK activation

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Increased expression of DNA-dependent protein kinase confers resistance to adriamycin

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Potentiation of chemosensitivity in multidrug-resistant human leukemia CEM cells by inhibition of DNA-dependent protein kinase using wortmannin

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

DNA repair inhibition and cancer therapy

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by adriamycin

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Synthesis, crystal structure determination, and biological properties of the DNA-dependent protein kinase (DNA-PK) inhibitor 3-cyano-6-hydrazonomethyl-5-(4-pyridyl)pyrid-[1H]-2-one (OK-1035).

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

DNA-dependent protein kinase is inhibited by trifluoperazine

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Binding of Ku and c-Abl at the Kinase Homology Region of DNA-dependent Protein Kinase Catalytic Subunit

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Advances in glyoxalase research. Glyoxalase expression in malignancy, anti-proliferative effects of methylglyoxal, glyoxalase I inhibitor diesters and S-D-lactoylglutathione, and methylglyoxal-modified protein binding and endocytosis by the advanced

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Catalytic and molecular properties of glyoxalase I.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glyoxalase II: molecular characteristics, kinetics and mechanism

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Differences among human tumor cell lines in the expression of glutathione transferases and other glutathione-linked enzymes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Nutritional and physiological consequences of tumour glycolysis

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Inhibition of proliferation of human leukaemia 60 cells by diethyl esters of glyoxalase inhibitors in vitro

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The hypothetical active site lattice. An approach to modelling active sites from data on inhibitor molecules

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Crystal structure of human glyoxalase I_evidence for gene duplication and 3D domain swapping

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Mutagenesis of residue 157 in the active site of human glyoxalase I

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Inhibition by glutathione derivatives of bovine liver glyoxalase II (hydroxyacylglutathione hydrolase) as a probe of the N- and S-sites for substrate binding

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Prevention of S-D-lactoylglutathione-induced inhibition of human leukaemia 60 cell growth by uridine

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Inhibition of human leukaemia 60 cell growth by S-D-lactoylglutathione in vitro. Mediation by metabolism to N-D-lactoylcysteine and induction of apoptosis

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Biological interactions of alpha,beta-unsaturated aldehydes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The ATP-dependent glutathione S-conjugate export pump

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The human multidrug resistance-associated protein (MRP) gene family: from biological function to drug molecular design

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

A family of drug transporters: the multidrug resistance-associated proteins.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The (patho)physiological functions of the MRP family

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Biology of the multidrug resistance-associated protein, MRP.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Function, evolution and structure of multidrug resistance protein (MRP).

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Adriamycin resistance in HL60 cells in the absence of detectable P-glycoprotein

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Structural, mechanistic and clinical aspects of MRP1.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Expression of the multidrug resistance-associated protein (MRP) gene in non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Significance of multi-drug-resistant proteins in predicting chemotherapy response and prognosis in epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Role of the multidrug resistance protein 1 gene in the carcinogenicity of aflatoxin B1: investigations using mrp1-null mice

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Modulation by (iso)flavonoids of the ATPase activity of the multidrug resistance protein

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Potent interaction of flavopiridol with MRP1

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Effects of clotrimazole on transport mediated by multidrug resistance associated protein 1 (MRP1) in human erythrocytes and tumour cells

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Inhibition of multidrug resistance-associated protein (MRP) functional activity with pluronic block copolymers.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

The sulphonylurea glibenclamide inhibits multidrug resistance protein (MRP1) activity in human lung cancer cells

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Reversal of MRP-mediated vincristine resistance in KB cells by buthionine sulfoximine in combination with PAK-104P.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

gamma-Glutamyl transpeptidase, a glutathionase: its expression and function in carcinogenesis

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Immunohistochemical detection of gamma-glutamyl transpeptidase in normal human tissue

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Mitochondrial changes associated with glutathione deficiency

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione and drug resistance

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Gamma-glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Expression of gamma-glutamyl transpeptidase provides tumor cells with a selective growth advantage at physiologic concentrations of cyst(e)ine

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Altered expression of gamma-glutamyl transpeptidase in human tumors

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Gamma-glutamyl transpeptidase immunoreactivity in benign and malignant breast tissue

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Glutathione and glutathione-dependent enzymes in ovarian adenocarcinoma cell lines derived from a patient before and after the onset of drug resistance: intrinsic differences and cell cycle effects.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Involvement of Ser-451 and Ser-452 in the Catalysis of Human γ-Glutamyl Transpeptidase

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Identification of catalytic nucleophile of Escherichia coli gamma-glutamyltranspeptidase by gamma-monofluorophosphono derivative of glutamic acid: N-terminal thr-391 in small subunit is the nucleophile

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Affinity labeling of gamma-glutamyl transpeptidase and location of the gamma-glutamyl binding site on the light subunit

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Slow-binding inhibition of gamma-glutamyl transpeptidase by gamma-boroGlu

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Development and evaluation of a boronate inhibitor of gamma-glutamyl transpeptidase

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Acivicin induces apoptosis independently of gamma-glutamyltranspeptidase activity

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Edible Mushroom (Agaricus bisporus) Lectin, Which Reversibly Inhibits Epithelial Cell Proliferation, Blocks Nuclear Localization Sequence-dependent Nuclear Protein Import

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

ATP-dependent glutathione S-conjugate 'export' pump in the vacuolar membrane of plants

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120015695

21 January 2018

Identifiers

10.1081/DMR-120015695

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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