Non-apoptotic Fas signaling. (Q35027104)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12485619%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

review article

1 reference

title

Non-apoptotic Fas signaling (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12485619%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12485619%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Klaus Pfizenmaier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12485619%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Peter Scheurich

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15 December 2019

publication date

1 February 2003

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Cytokine and Growth Factor Reviews

15 December 2019

published in

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15 December 2019

volume

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15 December 2019

issue

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15 December 2019

page(s)

53-66

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Monoclonal antibody-mediated tumor regression by induction of apoptosis.

15 December 2019

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Analysis of the oligomeric requirement for signaling by CD40 using soluble multimeric forms of its ligand, CD154

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Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5

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The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

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7 January 2021

Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.

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7 January 2021

Ultraviolet Light Induces Apoptosis via Direct Activation of CD95 (Fas/APO-1) Independently of Its Ligand CD95L

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7 January 2021

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

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7 January 2021

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.

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7 January 2021

Glutamine deprivation-mediated cell shrinkage induces ligand-independent CD95 receptor signaling and apoptosis

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Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas.

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Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

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7 January 2021

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7 January 2021

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7 January 2021

A role for FADD in T cell activation and development

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7 January 2021

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

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7 January 2021

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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7 January 2021

gld/gld mice are unable to express a functional ligand for Fas.

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7 January 2021

CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

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7 January 2021

Dichotomy between naïve and memory CD4(+) T cell responses to Fas engagement

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7 January 2021

Role of CD95-activated caspase-1 processing of IL-1beta in TCR-mediated proliferation of HIV-infected CD4(+) T cells.

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7 January 2021

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7 January 2021

Fas engagement accelerates liver regeneration after partial hepatectomy

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Maximal Proliferation of Cytotoxic T Lymphocytes Requires Reverse Signaling through Fas Ligand

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Fas ligand costimulates the in vivo proliferation of CD8+ T cells

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Interaction of peptides derived from the Fas ligand with the Fyn-SH3 domain

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The role of Fas ligand in immune privilege

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Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice

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Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

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7 January 2021

Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts.

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Gene transfer of Fas ligand induces tumor regression in vivo

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Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival

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7 January 2021

Decreased neutrophil adhesion to human cytomegalovirus-infected retinal pigment epithelial cells is mediated by virus-induced up-regulation of Fas ligand independent of neutrophil apoptosis

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7 January 2021

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7 January 2021

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7 January 2021

Bcl-2 Prevents CD95 (Fas/APO-1)-induced Degradation of Lamin B and Poly(ADP-ribose) Polymerase and Restores the NF-κB Signaling Pathway

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7 January 2021

Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

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7 January 2021

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

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7 January 2021

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The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

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7 January 2021

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7 January 2021

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

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7 January 2021

Protection against Fas-mediated and tumor necrosis factor receptor 1-mediated liver injury by blockade of FADD without loss of nuclear factor-kappaB activation

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7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

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Absent or reduced expression of the caspase 8 gene occurs frequently in neuroblastoma, but not commonly in Ewing sarcoma or rhabdomyosarcoma

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7 January 2021

Resistance to TRAIL-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.

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7 January 2021

Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.

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7 January 2021

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

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7 January 2021

Regulation of FasL by NF-κB and AP-1 in Fas-dependent Thymineless Death of Human Colon Carcinoma Cells

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7 January 2021

Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment

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7 January 2021

Signal transduction by the JNK group of MAP kinases

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7 January 2021

AP-1 as a regulator of cell life and death

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7 January 2021

Fas ligand, death gene.

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7 January 2021

Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1

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7 January 2021

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

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7 January 2021

Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.

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7 January 2021

MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis

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7 January 2021

JNK activation is not required for Fas-mediated apoptosis

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7 January 2021

MEK1 activation rescues Jurkat T cells from Fas-induced apoptosis

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7 January 2021

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

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7 January 2021

Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis

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7 January 2021

FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation

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7 January 2021

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

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7 January 2021

Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/SAPK and MKK6-p38 pathways independent of CPP32-like proteases.

1 reference

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7 January 2021

JNK/SAPK activity contributes to TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Sequestration and inhibition of Daxx-mediated transcriptional repression by PML

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Dissecting Fas signaling with an altered-specificity death-domain mutant: requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Inhibition of Daxx-mediated apoptosis by heat shock protein 27

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The cardiac Fas (APO-1/CD95) Receptor/Fas ligand system : relation to diastolic wall stress in volume-overload hypertrophy in vivo and activation of the transcription factor AP-1 in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Fas receptor signaling inhibits glycogen synthase kinase 3 beta and induces cardiac hypertrophy following pressure overload

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Signaling pathways for cardiac hypertrophy and failure

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH(2)-terminal kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Cardiac overexpression of a G(q) inhibitor blocks induction of extracellular signal-regulated kinase and c-Jun NH(2)-terminal kinase activity in in vivo pressure overload

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Fas-mediated stimulation induces IL-8 secretion by rheumatoid arthritis synoviocytes independently of CPP32-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Induction of interleukin-8 secretion and apoptosis in bronchiolar epithelial cells by Fas ligation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Ligation of the Fas antigen stimulates chemokine secretion in pancreatic cancer cell line PANC-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The membrane-bound but not the soluble form of human Fas ligand is responsible for its inflammatory activity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Fas ligand engagement of resident peritoneal macrophages in vivo induces apoptosis and the production of neutrophil chemotactic factors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The CD95 (APO-1/Fas) receptor activates NF-kappaB independently of its cytotoxic function

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Regulation of Fas-mediated apoptosis by NF-kappaB activity in human hepatocyte derived cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Differential requirement for NF-kappaB-inducing kinase in the induction of NF-kappaB by IL-1beta, TNF-alpha, and Fas.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

NF-kappaB signals induce the expression of c-FLIP.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The putative apoptosis inhibitor IEX-1L is a mutant nonspliced variant of p22(PRG1/IEX-1) and is not expressed in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

NF-kappaB-dependent MnSOD expression protects adenocarcinoma cells from TNF-alpha-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The c-Rel transcription factor can both induce and inhibit apoptosis in the same cells via the upregulation of MnSOD.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Phosphorylation of IκB-α Inhibits Its Cleavage by Caspase CPP32 in Vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900072-2

7 January 2021

10.1016/S1359-6101(02)00072-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12485619%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12485619%20AND%20SRC:MED&resulttype=core&format=json