PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer. (Q35024076)

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English	PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer.	scientific article

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27 January 2020

PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer (English)

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27 January 2020

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Kamila Naxerova

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27 January 2020

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Rakesh K Jain

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27 January 2020

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Tony Shi

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Dai Fukumura

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Peigen Huang

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Rekha Samuel

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Jieqiong Liu

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27 January 2020

Shan Liao

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27 January 2020

Yuhui Huang

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27 January 2020

Walid Kamoun

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27 January 2020

Lei Xu

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27 January 2020

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1 April 2011

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27 January 2020

Clinical Cancer Research

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27 January 2020

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27 January 2020

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27 January 2020

3638-3648

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27 January 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3107920/fullTextXML

based on heuristic

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Delivering nanomedicine to solid tumors

1 reference

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8 July 2018

3,3'-Diindolylmethane enhances taxotere-induced apoptosis in hormone-refractory prostate cancer cells through survivin down-regulation

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8 July 2018

PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment

1 reference

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8 July 2018

PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment

1 reference

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8 July 2018

Mammalian target of rapamycin repression by 3,3'-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC3 cells

1 reference

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8 July 2018

Pericytes: gatekeepers in tumour cell metastasis?

1 reference

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8 July 2018

Expression of endothelial PDGF receptors alpha and beta in breast cancer: up-regulation of endothelial PDGF receptor beta

1 reference

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8 July 2018

Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications

1 reference

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8 July 2018

Autocrine PDGFR signaling promotes mammary cancer metastasis

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8 July 2018

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1 reference

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8 July 2018

The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

Functions of CXCL12 and CXCR4 in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

Blocking platelet-derived growth factor-D/platelet-derived growth factor receptor beta signaling inhibits human renal cell carcinoma progression in an orthotopic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

1 reference

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8 July 2018

PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors

1 reference

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1 reference

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8 July 2018

What brings pericytes to tumor vessels?

1 reference

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8 July 2018

Molecular regulation of vessel maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

PDGF-D is a potent transforming and angiogenic growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

Platelet-derived growth factor D: tumorigenicity in mice and dysregulated expression in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

PDGF-D, a new protease-activated growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

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Involvement of chemokine receptors in breast cancer metastasis

1 reference

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8 July 2018

PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

Pericytes in the microvasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

8 July 2018

Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-κB signaling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107920

25 October 2018

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25 October 2018

Down-regulation of Platelet-Derived Growth Factor-D Inhibits Cell Growth and Angiogenesis through Inactivation of Notch-1 and Nuclear Factor-κB Signaling

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21459800

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Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21459800

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inferred from PubMed ID database lookup

Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast

1 reference

https://pubmed.ncbi.nlm.nih.gov/21459800

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inferred from PubMed ID database lookup

Cytoplasmic CXCR4 expression in breast cancer: induction by nitric oxide and correlation with lymph node metastasis and poor prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21459800

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based on heuristic

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10.1158/1078-0432.CCR-10-2456

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27 January 2020

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27 January 2020

PubMed publication ID

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27 January 2020

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