Mitochondrial dysfunction in patients with primary congenital insulin resistance (Q35015797)

5 August 2017

title

Mitochondrial dysfunction in patients with primary congenital insulin resistance (English)

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5 August 2017

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5 August 2017

Alison Sleigh

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Christine Burren

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Mensud Hatunic

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David B Savage

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Soren Brage

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Graham J Kemp

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Stephen O'Rahilly

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Kevin M Brindle

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5 August 2017

author name string

Philippa Raymond-Barker

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5 August 2017

Kerrie Thackray

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5 August 2017

David Porter

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5 August 2017

Alessandra Vottero

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5 August 2017

Catherine Mitchell

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5 August 2017

Martin McIntyre

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5 August 2017

T Adrian Carpenter

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5 August 2017

Peter R Murgatroyd

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5 August 2017

language of work or name

English

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publication date

9 May 2011

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Journal of Clinical Investigation

5 August 2017

published in

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5 August 2017

volume

121

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5 August 2017

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5 August 2017

page(s)

2457-2461

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Insulin signaling meets mitochondria in metabolism

5 August 2017

cites work

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8 July 2018

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Foxo1 integrates insulin signaling with mitochondrial function in the liver

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Lower intrinsic ADP-stimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male type 2 diabetic patients

8 July 2018

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Clinical features, diagnosis and management of maternally inherited diabetes and deafness (MIDD) associated with the 3243A>G mitochondrial point mutation

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Disordered lipid metabolism and the pathogenesis of insulin resistance

8 July 2018

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Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects.

8 July 2018

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Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

8 July 2018

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Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

8 July 2018

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Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts

8 July 2018

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Mitochondrial dysfunction in the elderly: possible role in insulin resistance

8 July 2018

1 reference

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Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

8 July 2018

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Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle

8 July 2018

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A receptor-mediated pathway for cholesterol homeostasis

8 July 2018

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31P NMR saturation-transfer measurements in Saccharomyces cerevisiae: characterization of phosphate exchange reactions by iodoacetate and antimycin A inhibition.

8 July 2018

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Skeletal muscle metabolism is a major determinant of resting energy expenditure

8 July 2018

1 reference

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Comparison of in vivo postexercise phosphocreatine recovery and resting ATP synthesis flux for the assessment of skeletal muscle mitochondrial function.

8 July 2018

1 reference

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The interpretation of abnormal 31P magnetic resonance saturation transfer measurements of Pi/ATP exchange in insulin-resistant skeletal muscle

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104774

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes

25 October 2018

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Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes

25 October 2018

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Challenges and Novel Approaches in the Epidemiological Study of Early Life Influences on Later Disease

25 October 2018

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Bioenergetics of intact human muscle. A 31P nuclear magnetic resonance study

25 October 2018

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12 December 2020

31P-NMR saturation transfer measurements of exchange between Pi and ATP in the reactions catalysed by glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase in vitro

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12 December 2020

31P NMR studies of ATP synthesis and hydrolysis kinetics in the intact myocardium

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12 December 2020

31P NMR magnetization-transfer measurements of ATP turnover during steady-state isometric muscle contraction in the rat hind limb in vivo

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12 December 2020

Effect of insulin deprivation on muscle mitochondrial ATP production and gene transcript levels in type 1 diabetic subjects

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12 December 2020

Identifiers

DOI

10.1172/JCI46405

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5 August 2017

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5 August 2017

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