Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3 (Q34973849)

5 August 2017

title

Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3 (English)

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5 August 2017

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5 August 2017

Anabela Silva-Fernandes

object named as

Anabela Silva-Fernandes

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Rui Gao

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5 August 2017

Yongping Liu

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5 August 2017

Xiang Fang

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5 August 2017

Adriana Paulucci-Holthauzen

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5 August 2017

Arpita Chatterjee

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5 August 2017

Hang L Zhang

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5 August 2017

Tohru Matsuura

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5 August 2017

Sanjeev Choudhary

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5 August 2017

Tetsuo Ashizawa

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5 August 2017

Arnulf H Koeppen

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5 August 2017

Tapas K Hazra

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5 August 2017

Partha S Sarkar

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5 August 2017

publication date

15 January 2015

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

e1004834

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Creative Commons CC0 License

5 August 2017

start time

15 January 2015

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April 2022 Public Data File from Crossref

copyrighted, dedicated to the public domain by copyright holder

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cites work

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin

8 July 2018

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Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene

8 July 2018

1 reference

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PUMA, a novel proapoptotic gene, is induced by p53

8 July 2018

1 reference

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Neuronal life and death: an essential role for the p53 family

8 July 2018

1 reference

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Linking DNA damage and neurodegeneration

8 July 2018

1 reference

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

8 July 2018

1 reference

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Glutamine repeats and neurodegeneration

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295939

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

8 July 2018

1 reference

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Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis

8 July 2018

1 reference

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Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation

8 July 2018

1 reference

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Interaction between ATM protein and c-Abl in response to DNA damage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295939

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

8 July 2018

1 reference

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Functional interaction between DNA-PK and c-Abl in response to DNA damage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295939

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

8 July 2018

1 reference

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Machado-Joseph disease: an autosomal dominant motor system degeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4295939

Spinocerebellar ataxia 3 and Machado-Joseph disease: clinical, molecular, and neuropathological features.

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

Autosomal dominant cerebellar ataxia type I. MRI-based volumetry of posterior fossa structures and basal ganglia in spinocerebellar ataxia types 1, 2 and 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

Association between Machado-Joseph disease and oxidative stress biomarkers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

Polyglutamine-expanded ataxin-7 upregulates Bax expression by activating p53 in cerebellar and inferior olivary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

Involvement of protein kinase C-delta in DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

Drosophila FMRP participates in the DNA damage response by regulating G2/M cell cycle checkpoint and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

Oxidative damage to mitochondrial DNA in Huntington's disease parietal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004834

A clinical and pathologic study of a large Japanese family with Machado-Joseph disease tightly linked to the DNA markers on chromosome 14q

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25590633

12 December 2020

inferred from PubMed ID database lookup

p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25590633

12 December 2020

inferred from PubMed ID database lookup

p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25590633

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PGEN.1004834

1 reference

release_lqh54rrp3rgh7cvl5k46ggwtt4

5 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lqh54rrp3rgh7cvl5k46ggwtt4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4295939

1 reference

5 August 2017

1 reference