Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection (Q34974604)

5 August 2017

title

Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection (English)

1 reference

5 August 2017

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Connie L Sommers

1 reference

5 August 2017

Jan Lee

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5 August 2017

Kevin L Steiner

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5 August 2017

Jordan M Gurson

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5 August 2017

Corinne L Depersis

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5 August 2017

Dalal El-Khoury

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5 August 2017

Claudette L Fuller

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5 August 2017

Elizabeth W Shores

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5 August 2017

Paul E Love

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5 August 2017

Lawrence E Samelson

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5 August 2017

language of work or name

English

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publication date

28 March 2005

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Journal of Experimental Medicine

5 August 2017

published in

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5 August 2017

volume

201

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5 August 2017

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5 August 2017

page(s)

1125-1134

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LAT: a T lymphocyte adapter protein that couples the antigen receptor to downstream signaling pathways

5 August 2017

cites work

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The Ras/MAPK cascade and the control of positive selection

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Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.

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8 July 2018

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Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT

8 July 2018

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Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells

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Tec family kinases modulate thresholds for thymocyte development and selection

8 July 2018

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Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

8 July 2018

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RasGRP links T-cell receptor signaling to Ras

8 July 2018

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A role for the Tec family tyrosine kinase Txk in T cell activation and thymocyte selection

8 July 2018

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Signals involved in thymocyte positive and negative selection

8 July 2018

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8 July 2018

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CD28-B7 interactions function to co-stimulate clonal deletion of double-positive thymocytes

8 July 2018

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Cellular and biochemical requirements for thymocyte negative selection

8 July 2018

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8 July 2018

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A role for calcium influx in setting the threshold for CD4+CD8+ thymocyte negative selection.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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LAT, the Linker for Activation of T Cells: A Bridge Between T Cell-Specific and General Signaling Pathways

8 July 2018

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Identification of the minimal tyrosine residues required for linker for activation of T cell function

21 January 2018

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Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells

21 January 2018

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T cells: getting a GRP on Ras.

21 January 2018

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A LAT mutation that inhibits T cell development yet induces lymphoproliferation

21 January 2018

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Induction of T helper type 2 immunity by a point mutation in the LAT adaptor

21 January 2018

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Continued maturation of thymic emigrants in the periphery

21 January 2018

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Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.

21 January 2018

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NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells

21 January 2018

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An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

21 January 2018

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Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors.

21 January 2018

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Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection

21 January 2018

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https://api.crossref.org/works/10.1084%2FJEM.20041869

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

21 January 2018

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Recent thymic emigrants are distinct from most medullary thymocytes

21 January 2018

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12 December 2020

Degree of ERK activation influences both positive and negative thymocyte selection

1 reference

12 December 2020

Involvement of p21ras activation in T cell CD69 expression

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12 December 2020

A shift from negative to positive selection of autoreactive T cells by the reduced level of TCR signal in TCR-transgenic CD3 zeta-deficient mice

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12 December 2020

Identifiers

DOI

10.1084/JEM.20041869

1 reference

release_jzd4v2oppvavdiyo6ar432wtr4

5 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jzd4v2oppvavdiyo6ar432wtr4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1538971

1 reference

5 August 2017

1 reference