Functional selectivity and time-dependence of μ-opioid receptor desensitization at nerve terminals in the mouse ventral tegmental area (Q34939735)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24467517%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Functional selectivity and time-dependence of μ-opioid receptor desensitization at nerve terminals in the mouse ventral tegmental area (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24467517%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

0 references

1 reference

1 reference

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6 March 2020

J D Lowe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24467517%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

language of work or name

English

0 references

publication date

1 July 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24467517%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

6 March 2020

published in

1 reference

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6 March 2020

volume

172

1 reference

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6 March 2020

issue

1 reference

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6 March 2020

page(s)

469-481

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24467517%20AND%20SRC:MED&resulttype=core&format=json

The Concise Guide to PHARMACOLOGY 2013/14: ion channels

6 March 2020

cites work

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The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors

8 July 2018

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G protein-gated inwardly rectifying potassium (KIR3) channels play a primary role in the antinociceptive effect of oxycodone, but not morphine, at supraspinal sites

8 July 2018

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Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.

8 July 2018

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μ-Opioid receptor desensitization: homologous or heterologous?

8 July 2018

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Morphine desensitization and cellular tolerance are distinguished in rat locus ceruleus neurons

8 July 2018

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Multiple inhibitory G-protein-coupled receptors resist acute desensitization in the presynaptic but not postsynaptic compartments of neurons

8 July 2018

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Opioid-sensitive GABA inputs from rostromedial tegmental nucleus synapse onto midbrain dopamine neurons

8 July 2018

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Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice.

8 July 2018

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8 July 2018

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Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies

8 July 2018

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Differential regulation of spontaneous and evoked neurotransmitter release at central synapses

8 July 2018

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Modulating micro-opioid receptor phosphorylation switches agonist-dependent signaling as reflected in PKCepsilon activation and dendritic spine stability.

8 July 2018

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Protein Kinase C-Mediated Phosphorylation of the μ-Opioid Receptor and Its Effects on Receptor Signaling

8 July 2018

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Differential Expression and Sensitivity of Presynaptic and Postsynaptic Opioid Receptors Regulating Hypothalamic Proopiomelanocortin Neurons

8 July 2018

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Morphine Induces μ Opioid Receptor Endocytosis in Guinea Pig Enteric Neurons Following Prolonged Receptor Activation

8 July 2018

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Tolerance to the Antinociceptive Effect of Morphine in the Absence of Short-Term Presynaptic Desensitization in Rat Periaqueductal Gray Neurons

8 July 2018

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Animal research: reporting in vivo experiments: the ARRIVE guidelines

8 July 2018

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Guidelines for reporting experiments involving animals: the ARRIVE guidelines

8 July 2018

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μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization

8 July 2018

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Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling

8 July 2018

1 reference

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Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.

8 July 2018

1 reference

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Agonist-selective mechanisms of GPCR desensitization

8 July 2018

1 reference

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Dynasore, a cell-permeable inhibitor of dynamin

8 July 2018

1 reference

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Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292961

GABA transporter currents activated by protein kinase A excite midbrain neurons during opioid withdrawal

8 July 2018

1 reference

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Contribution of GIRK2-mediated postsynaptic signaling to opiate and alpha 2-adrenergic analgesia and analgesic sex differences

8 July 2018

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mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization.

8 July 2018

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Desensitization of mu-opioid receptor-evoked potassium currents: initiation at the receptor, expression at the effector

8 July 2018

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Synthesis of a stable form of tertiapin: a high-affinity inhibitor for inward-rectifier K+ channels

8 July 2018

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Morphine-activated opioid receptors elude desensitization by beta-arrestin

8 July 2018

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How opioids inhibit GABA-mediated neurotransmission

8 July 2018

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A subset of ventral tegmental area neurons is inhibited by dopamine, 5-hydroxytryptamine and opioids

8 July 2018

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Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells

8 July 2018

1 reference

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Cellular mechanisms of opioid tolerance: studies in single brain neurons

8 July 2018

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Transient homologous mu-opioid receptor desensitization in rat locus coeruleus neurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292961

Opioids excite dopamine neurons by hyperpolarization of local interneurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292961

Two types of neurone in the rat ventral tegmental area and their synaptic inputs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292961

Protein kinase C activation enhances morphine-induced rapid desensitization of mu-opioid receptors in mature rat locus ceruleus neurons

8 July 2018

1 reference

Presynaptic mu-opioid receptors regulate a late step of the secretory process in rat ventral tegmental area GABAergic neurons

21 January 2018

1 reference

Two distinct forms of desensitization of G-protein coupled inwardly rectifying potassium currents evoked by alkaloid and peptide mu-opioid receptor agonists

21 January 2018

1 reference

Intracranial self-administration of morphine into the ventral tegmental area in rats.

21 January 2018

1 reference

Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area

21 January 2018

1 reference

C-terminal splice variants of the mouse mu-opioid receptor differ in morphine-induced internalization and receptor resensitization

21 January 2018

1 reference

The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons?

21 January 2018

1 reference

Spinal G-protein-gated K+ channels formed by GIRK1 and GIRK2 subunits modulate thermal nociception and contribute to morphine analgesia.

21 January 2018

1 reference

GABA(B) receptor activation desensitizes postsynaptic GABA(B) and A(1) adenosine responses in rat hippocampal neurones

21 January 2018

1 reference

Nucleus Accumbens Medium Spiny Neurons Target Non-Dopaminergic Neurons in the Ventral Tegmental Area

21 January 2018

1 reference

Mu-opioid receptor desensitization in mature rat neurons: lack of interaction between DAMGO and morphine.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292961

Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292961

Receptor density and recycling affect the rate of agonist-induced desensitization of mu-opioid receptor

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292961

Agonist induced homologous desensitization of mu-opioid receptors mediated by G protein-coupled receptor kinases is dependent on agonist efficacy.

26 October 2018

1 reference

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Ultrastructural relationships between terminals immunoreactive for enkephalin, GABA, or both transmitters in the rat ventral tegmental area

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24467517

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased probability of GABA release during withdrawal from morphine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24467517

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Presynaptic receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24467517

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/BPH.12605

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24467517%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24467517%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

24467517

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24467517%20AND%20SRC:MED&resulttype=core&format=json