Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth (Q34922227)

5 August 2017

title

Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth (English)

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5 August 2017

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head and neck carcinoma

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Paul L Leong

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5 August 2017

Genevieve A Andrews

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5 August 2017

Daniel E Johnson

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5 August 2017

Kevin F Dyer

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5 August 2017

Sichuan Xi

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5 August 2017

Jeffrey C Mai

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5 August 2017

Paul D Robbins

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5 August 2017

Seshu Gadiparthi

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5 August 2017

Nancy A Burke

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5 August 2017

Simon F Watkins

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5 August 2017

Jennifer Rubin Grandis

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5 August 2017

language of work or name

English

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publication date

14 March 2003

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Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

published in

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5 August 2017

volume

100

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5 August 2017

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5 August 2017

page(s)

4138-4143

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Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma.

5 August 2017

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Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

8 July 2018

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Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1

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8 July 2018

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8 July 2018

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Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

8 July 2018

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Targeted disruption of stat6 DNA binding activity by an oligonucleotide decoy blocks IL-4-driven T(H)2 cell response

8 July 2018

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Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein

8 July 2018

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Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

8 July 2018

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8 July 2018

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Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells

8 July 2018

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ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases

8 July 2018

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Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

8 July 2018

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

8 July 2018

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Dual blockade of cyclic AMP response element- (CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide. gene-specific inhibition of tumor growth

8 July 2018

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Growth inhibition of cultured human Tenon's fibroblastic cells by targeting the E2F transcription factor

8 July 2018

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Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

8 July 2018

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

8 July 2018

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Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

8 July 2018

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A novel strategy for myocardial protection using in vivo transfection of cis element 'decoy' against NFkappaB binding site: evidence for a role of NFkappaB in ischemia-reperfusion injury

8 July 2018

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STATs and Gene Regulation

8 July 2018

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Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines.

8 July 2018

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8 July 2018

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A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells

8 July 2018

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8 July 2018

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Transcription factor decoy approach to decipher the role of NF-kappa B in oncogenesis

8 July 2018

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8 July 2018

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HER-2/neu Oncogene Characterization in Head and Neck Squamous Cell Carcinoma

8 July 2018

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8 July 2018

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Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines.

8 July 2018

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Monocyte killing of human squamous epithelial cells: role for thrombospondin

8 July 2018

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Regulation of gene expression with double-stranded phosphorothioate oligonucleotides

8 July 2018

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The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter

8 July 2018

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Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

8 July 2018

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Constitutive activation of stat 3 oncogene product in human ovarian carcinoma cells.

21 January 2018

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Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines

21 January 2018

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Epidermal growth factor receptor--mediated stat3 signaling blocks apoptosis in head and neck cancer

21 January 2018

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Enhancement of cytosine arabinoside-induced apoptosis in human myeloblastic leukemia cells by NF-kappa B/Rel- specific decoy oligodeoxynucleotides

21 January 2018

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Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo.

21 January 2018

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STAT3 activation abrogates growth factor dependence and contributes to head and neck squamous cell carcinoma tumor growth in vivo

26 October 2018

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12 December 2020

Site-specific gene expression in vivo by direct gene transfer into the arterial wall

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12 December 2020

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

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12 December 2020

Participation of JAK, STAT and unknown proteins in human placental lactogen-induced signaling: a unique signaling pathway different from prolactin and growth hormone

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12 December 2020

Retinoic acid normalizes the increased gene transcription rate of TGF-alpha and EGFR in head and neck cancer cell lines

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12 December 2020

Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors

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12 December 2020

Sustained loss of a neoplastic phenotype by brief inactivation of MYC

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0534764100

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release_xs7s4u64tfeo7gvoggjrnvc7jm

5 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xs7s4u64tfeo7gvoggjrnvc7jm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

153061

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5 August 2017

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