Loss of the Notch effector RBPJ promotes tumorigenesis (Q34924659)

5 August 2017

title

Loss of the Notch effector RBPJ promotes tumorigenesis (English)

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5 August 2017

Nelson Wong

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Steven Jones

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Linda Chang

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5 August 2017

Blake Gilks

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5 August 2017

Iva Kulic

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5 August 2017

Gordon Robertson

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5 August 2017

Jennifer H E Baker

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5 August 2017

William W Lockwood

1 reference

5 August 2017

Winnie Mok

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5 August 2017

Megan Fuller

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5 August 2017

Michèle Fournier

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5 August 2017

Vennie Chou

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5 August 2017

Mark D Robinson

1 reference

5 August 2017

Hye-Jung Chun

1 reference

5 August 2017

Bettina Kempkes

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5 August 2017

Thomas A Thomson

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5 August 2017

Martin Hirst

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5 August 2017

Andrew I Minchinton

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5 August 2017

Wan L Lam

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5 August 2017

Marco Marra

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5 August 2017

Aly Karsan

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5 August 2017

language of work or name

English

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publication date

15 December 2014

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Journal of Experimental Medicine

5 August 2017

published in

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5 August 2017

volume

212

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5 August 2017

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5 August 2017

page(s)

37-52

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The Notch signaling pathway as a mediator of tumor survival

5 August 2017

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division.

8 July 2018

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Rbpj conditional knockout reveals distinct functions of Notch4/Int3 in mammary gland development and tumorigenesis

8 July 2018

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8 July 2018

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Slug is a direct Notch target required for initiation of cardiac cushion cellularization

8 July 2018

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A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers

8 July 2018

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8 July 2018

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Notch signaling mediates hypoxia-induced tumor cell migration and invasion

8 July 2018

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DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers.

8 July 2018

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A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling

8 July 2018

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Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin

8 July 2018

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Notch and cancer: a double-edged sword

8 July 2018

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8 July 2018

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8 July 2018

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Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.

8 July 2018

1 reference

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8 July 2018

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High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

8 July 2018

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A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 independent

8 July 2018

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8 July 2018

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The role of hypoxia-induced factors in tumor progression

8 July 2018

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Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA

8 July 2018

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Viral interactions with the Notch pathway

8 July 2018

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Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-Jkappa

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex

8 July 2018

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8 July 2018

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Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

8 July 2018

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8 July 2018

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Biochemical and immunological characterization of the DNA binding protein (RBP-J kappa) to mouse J kappa recombination signal sequence

8 July 2018

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BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice

8 July 2018

1 reference

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Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase.

21 January 2018

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21 January 2018

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Microregional effects of gemcitabine in HCT-116 xenografts

21 January 2018

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Predicting transcription factor affinities to DNA from a biophysical model

21 January 2018

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Pscan: finding over-represented transcription factor binding site motifs in sequences from co-regulated or co-expressed genes

21 January 2018

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21 January 2018

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26 October 2018

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12 December 2020

Smooth Muscle alpha-actin is a direct target of Notch/CSL

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Identifiers

DOI

10.1084/JEM.20121192

1 reference

5 August 2017

1 reference

5 August 2017

1 reference