N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis. (Q34904630)

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English	N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.	scientific article

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23 January 2020

N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis (English)

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23 January 2020

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23 January 2020

Kristen Nordick

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23 January 2020

V Michael Holers

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V Michael Holers

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23 January 2020

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Van C Willis

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23 January 2020

Alison M Gizinski

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Nirmal K Banda

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Corey P Causey

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Yuan Luo

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Brandt Levitt

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Magdalena Glogowska

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Piyanka Chandra

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Liudmila Kulik

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William H Robinson

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William P Arend

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Paul R Thompson

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23 February 2011

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23 January 2020

Journal of Immunology

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23 January 2020

4396-4404

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23 January 2020

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity

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8 July 2018

Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis.

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8 July 2018

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation.

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8 July 2018

Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4.

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8 July 2018

CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells

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8 July 2018

Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination.

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8 July 2018

Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation

1 reference

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8 July 2018

Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation

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8 July 2018

Regulation of p53 target gene expression by peptidylarginine deiminase 4

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8 July 2018

Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis

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8 July 2018

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

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8 July 2018

Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility

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8 July 2018

Protein arginine deiminase 4: evidence for a reverse protonation mechanism

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8 July 2018

Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.

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8 July 2018

Cutting edge: unique T cells that recognize citrullinated peptides are a feature of protein immunization

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8 July 2018

Diagnostic and predictive value of anti-cyclic citrullinated protein antibodies in rheumatoid arthritis: a systematic literature review

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8 July 2018

Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085980

8 July 2018

Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes

1 reference

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8 July 2018

Human PAD4 regulates histone arginine methylation levels via demethylimination

1 reference

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8 July 2018

Histone deimination antagonizes arginine methylation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085980

8 July 2018

Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6

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8 July 2018

Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors

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8 July 2018

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085980

8 July 2018

ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085980

8 July 2018

Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes

1 reference

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8 July 2018

Significance analysis of microarrays applied to the ionizing radiation response

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8 July 2018

Citrullination: a small change for a protein with great consequences for rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085980

8 July 2018

Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3085980

8 July 2018

Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3)

1 reference

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8 July 2018

Cluster analysis and display of genome-wide expression patterns

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8 July 2018

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies

1 reference

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8 July 2018

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Genetic susceptibility to murine collagen II autoimmune arthritis. Proposed relationship to the IgG2 autoantibody subclass response, complement C5, major histocompatibility complex (MHC) and non-MHC loci

1 reference

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8 July 2018

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1 reference

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1 reference

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1 reference

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Antigen microarray profiling of autoantibodies in rheumatoid arthritis.

1 reference

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26 October 2018

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1 reference

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26 October 2018

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1 reference

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26 October 2018

Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis

1 reference

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26 October 2018

Citrullination of synovial proteins in murine models of rheumatoid arthritis

1 reference

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26 October 2018

Peptidylarginine deiminase: a candidate factor in demyelinating disease

1 reference

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1 reference

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26 October 2018

Diagnostic accuracy of the anti-citrulline antibody assay for rheumatoid arthritis

1 reference

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26 October 2018

The developmental expression and activity of peptidylarginine deiminase in the mouse

1 reference

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26 October 2018

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1 reference

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9 December 2018

A colorimetric 96-well microtiter plate assay for the determination of enzymatically formed citrulline

1 reference

https://pubmed.ncbi.nlm.nih.gov/21346230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21346230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of reported genetic associations of PADI4, FCRL3, SLC22A4 and RUNX1 genes with rheumatoid arthritis: results of an independent Japanese population and evidence from meta-analysis of East Asian studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21346230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dual action of rheumatoid arthritis synovial fibroblast IL-15 expression on the equilibrium between CD4+CD25+ regulatory T cells and CD4+CD25- responder T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21346230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of effects of complement inhibition in murine collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21346230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Can we accurately predict the development of rheumatoid arthritis in the preclinical phase?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21346230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21346230

12 December 2020

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inferred from PubMed ID database lookup

Combination benefit of treatment with the cytokine inhibitors interleukin-1 receptor antagonist and PEGylated soluble tumor necrosis factor receptor type I in animal models of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21346230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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23 January 2020

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23 January 2020

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23 January 2020

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