Endocytic regulation of TGF-beta signaling (Q34892916)

5 August 2017

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title

Endocytic regulation of TGF-beta signaling (English)

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5 August 2017

Ye-Guang Chen

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5 August 2017

publication date

1 January 2009

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5 August 2017

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inferred from page(s)

published in

Cell Research

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

58-70

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Role of transforming growth factor beta in human disease

5 August 2017

cites work

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https://api.crossref.org/works/10.1038%2FCR.2008.315

TGFbeta signaling in growth control, cancer, and heritable disorders

21 January 2018

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Regulation of TGF-beta signaling and its roles in progression of tumors

21 January 2018

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Smads and early developmental signaling by the TGFbeta superfamily

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Negative regulation of TGF-beta signaling in development

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Extracellular control of TGFbeta signalling in vascular development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Regulation of Smad activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

New insights into TGF-beta-Smad signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Specificity and versatility in tgf-beta signaling through Smads

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

TGF-β signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

TGF-beta signal transduction

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Signal dispersal and transduction through the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Regulated portals of entry into the cell

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Signaling on the endocytic pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Regulation of signal transduction by endocytosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Signal transduction and endocytosis: close encounters of many kinds

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Modulation of developmental signals by endocytosis: different means and many ends.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Functions of lipid rafts in biological membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Clathrin-coated vesicle formation and protein sorting: an integrated process

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Clathrin-mediated endocytosis: membrane factors pull the trigger

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Coat proteins: shaping membrane transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Dynamin and its role in membrane fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

A role for lipid shells in targeting proteins to caveolae, rafts, and other lipid domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Lipid rafts: elusive or illusive?

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Caveolae: anchored, multifunctional platforms in the lipid ocean

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Caveolae/raft-dependent endocytosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2008.315

Endocytosis without clathrin coats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Morphogen transport along epithelia, an integrated trafficking problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

The Decapentaplegic morphogen gradient: a precise definition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Internalization of transforming growth factor-beta and its receptor in BALB/c 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Transforming growth factor (TGF)-beta 1 internalization: modulation by ligand interaction with TGF-beta receptors types I and II and a mechanism that is distinct from clathrin-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

21 January 2018

TGF-β receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Chimeric granulocyte/macrophage colony-stimulating factor/transforming growth factor-beta (TGF-beta) receptors define a model system for investigating the role of homomeric and heteromeric receptors in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Distinct Endocytic Responses of Heteromeric and Homomeric Transforming Growth Factor β Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Transforming growth factor beta receptor signaling and endocytosis are linked through a COOH terminal activation motif in the type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Transforming growth factor beta activates Smad2 in the absence of receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Mechanisms of transforming growth factor-beta receptor endocytosis and intracellular sorting differ between fibroblasts and epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Ligand-dependent and -independent transforming growth factor-beta receptor recycling regulated by clathrin-mediated endocytosis and Rab11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Rab proteins as membrane organizers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Receptor internalization-independent activation of Smad2 in activin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Mechanism of TGFβ receptor inhibition by FKBP12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Heteromeric and homomeric transforming growth factor-beta receptors show distinct signaling and endocytic responses in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Sara endosomes and the maintenance of Dpp signaling levels across mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Early endosomal regulation of Smad-dependent signaling in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Endofin acts as a Smad anchor for receptor activation in BMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Hrs mediates downregulation of multiple signalling receptors in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Rapid flux in transforming growth factor-beta receptors on bone cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Processing of the transforming growth factor beta type I and II receptors. Biosynthesis and ligand-induced regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Zebrafish Dpr2 inhibits mesoderm induction by promoting degradation of nodal receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Down-regulation of transforming growth factor-beta receptors: cooperativity between the types I, II, and III receptors and modulation at the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

A nuclear antagonistic mechanism of inhibitory Smads in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

The ADAMs family of metalloproteases: multidomain proteins with multiple functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Cellular heparan sulfate negatively modulates transforming growth factor-beta1 (TGF-beta1) responsiveness in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

TGF-beta receptor function in the endothelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Caveolin-1 interacts and cooperates with the transforming growth factor-beta type I receptor ALK1 in endothelial caveolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Caveolin-1 increases basal and TGF-beta1-induced expression of type I procollagen through PI-3 kinase/Akt/mTOR pathway in human dermal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Transforming growth factor-beta receptors localize to caveolae and regulate endothelial nitric oxide synthase in normal human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Lateral diffusion of TGF-beta type I receptor studied by single-molecule imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

The evolutionally conserved activity of Dapper2 in antagonizing TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Zebrafish Dapper1 and Dapper2 play distinct roles in Wnt-mediated developmental processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Transduction of receptor signals by beta-arrestins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Identification and characterization of a PDZ protein that interacts with activin type II receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

Non-Smad TGF-beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

7 January 2021

Differential requirement for type I and type II transforming growth factor beta receptor kinase activity in ligand-mediated receptor endocytosis

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

7 January 2021

FKBP12 is a negative regulator of transforming growth factor-beta receptor internalization

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

7 January 2021

Thrombin induces endocytosis of endoglin and type-II TGF-beta receptor and down-regulation of TGF-beta signaling in endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

7 January 2021

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

7 January 2021

Biosynthesis of the type I and type II TGF-beta receptors. Implications for complex formation

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

7 January 2021

Regulating the stability of TGFbeta receptors and Smads

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.315

7 January 2021

Identifiers

DOI

10.1038/CR.2008.315

1 reference

Dimensions Publication ID

5 August 2017

1051311146

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