Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma (Q34887442)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029422%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma (English)

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17 January 2020

main subject

phase I clinical trial

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17 January 2020

Vernon K Sondak

1 reference

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17 January 2020

Ronald C DeConti

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17 January 2020

Stephanie Andrews

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17 January 2020

Patricia Urbas

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17 January 2020

Adam I Riker

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17 January 2020

Pamela N Munster

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17 January 2020

Daniel M Sullivan

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17 January 2020

Kenneth E Ugen

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17 January 2020

Jane L Messina

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17 January 2020

Richard Heller

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17 January 2020

language of work or name

English

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publication date

24 November 2008

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Journal of Clinical Oncology

17 January 2020

published in

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17 January 2020

volume

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17 January 2020

issue

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17 January 2020

page(s)

5896-5903

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Interleukin-12: biological properties and clinical application

17 January 2020

cites work

1 reference

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8 July 2018

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Nonviral gene delivery: what we know and what is next

8 July 2018

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Electrotransfer as a non viral method of gene delivery

8 July 2018

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Gene therapy: science fiction or reality?

8 July 2018

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8 July 2018

Cancer statistics, 2007

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Chemotherapy for metastatic melanoma: time for a change?

8 July 2018

1 reference

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Update on therapy for melanoma: opportunities for patient selection and overcoming tumor resistance

8 July 2018

1 reference

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Recent clinical progress in virus-based therapies for cancer.

8 July 2018

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In vivo electroporation for gene therapy

8 July 2018

1 reference

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Gene therapy progress and prospects: non-viral gene therapy by systemic delivery.

8 July 2018

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Cancer regression in patients after transfer of genetically engineered lymphocytes

8 July 2018

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Measures of response: RECIST, WHO, and new alternatives

8 July 2018

1 reference

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Gene therapy of cancer based on interleukin 12.

8 July 2018

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Viral gene therapy strategies: from basic science to clinical application

8 July 2018

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Immunotherapy as part of a multidisciplinary approach to melanoma treatment

8 July 2018

1 reference

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Phase I study of the intratumoral administration of recombinant canarypox viruses expressing B7.1 and interleukin 12 in patients with metastatic melanoma

8 July 2018

1 reference

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Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

8 July 2018

1 reference

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Electrochemotherapy: results of cancer treatment using enhanced delivery of bleomycin by electroporation

8 July 2018

1 reference

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Efficacy and safety of HLA-B7/beta-2 microglobulin plasmid DNA/lipid complex (Allovectin-7) in patients with metastatic melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645111

Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: ability to maintain IFN-gamma induction is associated with clinical response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645111

High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993

8 July 2018

1 reference

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Treatment of cutaneous and subcutaneous tumors with electrochemotherapy using intralesional bleomycin

8 July 2018

1 reference

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First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response

8 July 2018

1 reference

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Phase I study of direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7, in patients with metastatic melanoma

8 July 2018

1 reference

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Phase 2 trial of Allovectin-7 in advanced metastatic melanoma

8 July 2018

1 reference

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Evaluation of toxicity following electrically mediated interleukin-12 gene delivery in a B16 mouse melanoma model

26 October 2018

1 reference

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IL-12 gene therapy using an electrically mediated nonviral approach reduces metastatic growth of melanoma

26 October 2018

1 reference

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Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene--a phase I/II clinical protocol.

26 October 2018

1 reference

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Gene therapy of cancer with interleukin-12.

26 October 2018

1 reference

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IL-12 plasmid delivery by in vivo electroporation for the successful treatment of established subcutaneous B16.F10 melanoma

26 October 2018

1 reference

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Regression of tumor growth and induction of long-term antitumor memory by interleukin 12 electro-gene therapy

26 October 2018

1 reference

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Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: outcome of a phase I study

26 October 2018

1 reference

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Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation

26 October 2018

1 reference

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Electroporation-mediated interleukin-12 gene therapy for hepatocellular carcinoma in the mice model

26 October 2018

1 reference

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Intratumoral injection of IL-12 plasmid DNA--results of a phase I/IB clinical trial

26 October 2018

1 reference

12 December 2020

Phase II study of direct intralesional gene transfer of allovectin-7, an HLA-B7/beta2-microglobulin DNA-liposome complex, in patients with metastatic melanoma

1 reference

12 December 2020

Clinical and immunologic effects of subcutaneously administered interleukin-12 and interferon alfa-2b: phase I trial of patients with metastatic renal cell carcinoma or malignant melanoma

1 reference

12 December 2020

Phase II clinical trial of interleukin-12 in patients with relapsed and refractory non-Hodgkin's lymphoma and Hodgkin's disease

1 reference

12 December 2020

Immunotherapy of advanced malignancy by direct gene transfer of an interleukin-2 DNA/DMRIE/DOPE lipid complex: phase I/II experience

1 reference

12 December 2020

Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: clinical efficacy

1 reference

12 December 2020

Identifiers

DOI

10.1200/JCO.2007.15.6794

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029422%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029422%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

19029422

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029422%20AND%20SRC:MED&resulttype=core&format=json