Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis. (Q34870720)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21493775%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis (English)

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28 January 2020

1 reference

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28 January 2020

1 reference

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28 January 2020

P Darwin Bell

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28 January 2020

Wayne Fitzgibbon

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28 January 2020

Antine E Stenbit

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28 January 2020

May Amria

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28 January 2020

Amber Houston

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28 January 2020

Ryan Reichert

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28 January 2020

Sandra Gilley

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28 January 2020

Gene P Siegal

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28 January 2020

Mehmet Bilgen

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28 January 2020

Peter Cheng-te Chou

1 reference

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28 January 2020

Lisa Guay-Woodford

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28 January 2020

Brad Yoder

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28 January 2020

Courtney J Haycraft

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28 January 2020

Brian Siroky

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28 January 2020

publication date

14 April 2011

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Journal of the American Society of Nephrology

28 January 2020

published in

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28 January 2020

volume

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28 January 2020

issue

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28 January 2020

page(s)

839-848

1 reference

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Glomerulocystic kidney disease

28 January 2020

cites work

1 reference

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Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1.

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Ciliary biology: understanding the cellular and genetic basis of human ciliopathies

8 July 2018

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The role of the mammalian target of rapamycin (mTOR) in renal disease

8 July 2018

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Polycystins and primary cilia: primers for cell cycle progression

8 July 2018

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S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy

8 July 2018

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8 July 2018

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Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways

8 July 2018

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Renal injury is a third hit promoting rapid development of adult polycystic kidney disease

8 July 2018

1 reference

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Renal involvement in tuberous sclerosis complex and von Hippel-Lindau disease: shared disease mechanisms?

8 July 2018

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Pkd1 inactivation induced in adulthood produces focal cystic disease

8 July 2018

1 reference

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Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.

8 July 2018

1 reference

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A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

8 July 2018

1 reference

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Overexpression of innate immune response genes in a model of recessive polycystic kidney disease

8 July 2018

1 reference

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Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease

8 July 2018

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Renal cystic disease: the role of the primary cilium/centrosome complex in pathogenesis

8 July 2018

1 reference

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mTOR is out of control in polycystic kidney disease

8 July 2018

1 reference

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The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

8 July 2018

1 reference

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Cellular and molecular derangements in acute tubular necrosis

8 July 2018

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Murine models of polycystic kidney disease: molecular and therapeutic insights

8 July 2018

1 reference

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The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

8 July 2018

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8 July 2018

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Cellular events in renal hypertrophy

8 July 2018

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Tubuloglomerular feedback responses to acute contralateral nephrectomy

8 July 2018

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Reversible compensatory hypertrophy in transplanted brown Norway rat kidneys

8 July 2018

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Reactive oxygen species mediate compensatory glomerular hypertrophy in rat uninephrectomized kidney.

8 July 2018

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The growing importance of mTORC1-S6K1 signaling in kidney.

26 October 2018

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The TSC-mTOR signaling pathway regulates the innate inflammatory response

26 October 2018

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Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice

26 October 2018

1 reference

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Unilateral nephrectomy leads to up-regulation of syndecan-2- and TGF-beta-mediated glomerulosclerosis in syndecan-4 deficient male mice

26 October 2018

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Angiotensin converting enzyme activity in compensatory renal hypertrophy.

26 October 2018

1 reference

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Intraflagellar transport is essential for endochondral bone formation.

26 October 2018

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Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy

26 October 2018

1 reference

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Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease

26 October 2018

1 reference

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Renal sympathetic nerve activity and the weight of the remaining kidney in unilateral nephrectomized rats

26 October 2018

1 reference

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Dominantly transmitted glomerulocystic kidney disease: a distinct genetic entity.

26 October 2018

1 reference

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Tubular sodium handling and tubuloglomerular feedback in compensatory renal hypertrophy

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21493775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reversible compensatory hypertrophy in rat kidneys: morphometric characterization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21493775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Polycystic kidney disease evaluation by magnetic resonance imaging in ischemia-reperfusion injured PKD1 knockout mouse model: comparison of T2-weighted FSE and true-FISP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21493775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1681/ASN.2010050526

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21493775%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21493775%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

21493775

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21493775%20AND%20SRC:MED&resulttype=core&format=json