Unique risk factors for insertional mutagenesis in a mouse model of XSCID gene therapy (Q34830822)

4 August 2017

title

Unique risk factors for insertional mutagenesis in a mouse model of XSCID gene therapy (English)

1 reference

4 August 2017

0 references

Yan Shou

1 reference

4 August 2017

Zhijun Ma

series ordinal

1 reference

4 August 2017

Taihe Lu

series ordinal

1 reference

4 August 2017

Brian P Sorrentino

series ordinal

1 reference

4 August 2017

language of work or name

English

0 references

publication date

24 July 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

1 reference

4 August 2017

volume

103

1 reference

4 August 2017

1 reference

4 August 2017

page(s)

11730-11735

1 reference

Gene therapy: therapeutic gene causing lymphoma

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Genotoxicity of retroviral integration in hematopoietic cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

SLAM family receptors and SAP-related adaptors: matters arising

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Prospective isolation of murine hematopoietic stem cells by expression of an Abcg2/GFP allele

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Cloning and characterisation of the RBCC728/TRIM36 zinc-binding protein from the tumor suppressor gene region at chromosome 5q22.3.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

RTCGD: retroviral tagged cancer gene database

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Side effects of retroviral gene transfer into hematopoietic stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Lymphoid development and function in X-linked severe combined immunodeficiency mice after stem cell gene therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

A chromatin insulator protects retrovirus vectors from chromosomal position effects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Genomic alterations of the p19ARF encoding exons in T-cell acute lymphoblastic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Molecular cloning and characterization of the gene encoding mouse melanoma antigen by cDNA library transfection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603635103

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603635103

LMO2 and gene therapy for severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603635103

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603635103

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603635103

Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603635103

Polyclonal long-term repopulating stem cell clones in a primate model

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0603635103

Restoration of lymphoid populations in a murine model of X-linked severe combined immunodeficiency by a gene-therapy approach

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Tumor spectrum in ARF-deficient mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518804

Stable and functional lymphoid reconstitution of common cytokine receptor gamma chain deficient mice by retroviral-mediated gene transfer

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16864781

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Murine leukemia induced by retroviral gene marking

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16864781

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Safety of retroviral gene marking with a truncated NGF receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16864781

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0603635103

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference