Are vitamin and mineral deficiencies a major cancer risk? (Q34810438)

4 August 2017

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title

Are vitamin and mineral deficiencies a major cancer risk? (English)

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4 August 2017

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Bruce N Ames

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4 August 2017

Patricia Wakimoto

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4 August 2017

language of work or name

English

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publication date

1 September 2002

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4 August 2017

published in

Nature Reviews Cancer

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4 August 2017

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4 August 2017

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4 August 2017

page(s)

694-704

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Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress

4 August 2017

cites work

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Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

31 March 2020

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Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid

31 March 2020

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High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased K(m)): relevance to genetic disease and polymorphisms

31 March 2020

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DNA damage from micronutrient deficiencies is likely to be a major cause of cancer

31 March 2020

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Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

31 March 2020

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Ascorbic acid protects against endogenous oxidative DNA damage in human sperm

31 March 2020

1 reference

31 March 2020

Diet and breast cancer

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Can diet affect prostate cancer?

31 March 2020

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Meat consumption and cancer of the large bowel

31 March 2020

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31 March 2020

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Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence

31 March 2020

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31 March 2020

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Vegetables, fruit, and cancer prevention: a review

31 March 2020

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Fruit, vegetables, dietary fiber, and risk of colorectal cancer

31 March 2020

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Fruits, Vegetables, and Adenomatous Polyps : The Minnesota Cancer Prevention Research Unit Case-Control Study

31 March 2020

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Intake of fruits and vegetables and risk of breast cancer: a pooled analysis of cohort studies

31 March 2020

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Vegetable and fruit consumption and risks of colon and rectal cancer in a prospective cohort study: The Netherlands Cohort Study on Diet and Cancer

31 March 2020

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Whole grain food intake and cancer risk

31 March 2020

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Whole-grain intake and cancer: an expanded review and meta-analysis

31 March 2020

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Vegetables, fruit, and cancer. II. Mechanisms.

31 March 2020

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Cruciferous vegetables and cancer prevention

31 March 2020

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Strategies for cancer prevention: the role of diet

31 March 2020

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Cancer prevention and diet: help from single nucleotide polymorphisms

31 March 2020

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31 March 2020

Hormonal carcinogenesis

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Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog

31 March 2020

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A critical evaluation of the application of biomarkers in epidemiological studies on diet and health

31 March 2020

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Paracelsus to parascience: the environmental cancer distraction

31 March 2020

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What do animal cancer tests tell us about human cancer risk?: Overview of analyses of the carcinogenic potency database

31 March 2020

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Alcohol, low-methionine--low-folate diets, and risk of colon cancer in men

31 March 2020

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Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study

31 March 2020

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Dietary folate consumption and breast cancer risk

31 March 2020

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A Prospective Study of Folate Intake and the Risk of Breast Cancer

31 March 2020

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Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers

31 March 2020

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Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers

31 March 2020

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Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro

31 March 2020

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Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults

31 March 2020

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Micronutrients and genomic stability: a new paradigm for recommended dietary allowances (RDAs).

31 March 2020

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B-vitamin intake, metabolic genes, and colorectal cancer risk (United States).

31 March 2020

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Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults

31 March 2020

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Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia

31 March 2020

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Low seminal plasma folate concentrations are associated with low sperm density and count in male smokers and nonsmokers

31 March 2020

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Folate, vitamin B12, homocysteine status and chromosome damage rate in lymphocytes of older men

31 March 2020

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Micronucleus frequency in human lymphocytes is related to plasma vitamin B12 and homocysteine

31 March 2020

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A case-control study of diet and prostate cancer

31 March 2020

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Association of the B-vitamins pyridoxal 5'-phosphate (B(6)), B(12), and folate with lung cancer risk in older men.

31 March 2020

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Elevated serum homocysteine levels and increased risk of invasive cervical cancer in US women

31 March 2020

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Oxidants, antioxidants, and the degenerative diseases of aging

31 March 2020

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Nutrition and stomach cancer

31 March 2020

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Effect of physiological concentrations of vitamin C on gastric cancer cells and Helicobacter pylori

31 March 2020

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Oxidative DNA damage in human white blood cells in dietary antioxidant intervention studies

31 March 2020

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Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance

31 March 2020

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Citrus fruit supplementation reduces lipoprotein oxidation in young men ingesting a diet high in saturated fat: presumptive evidence for an interaction between vitamins C and E in vivo

31 March 2020

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Can antioxidant vitamins materially reduce oxidative damage in humans?

31 March 2020

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Epidemiologic evidence for vitamin C and vitamin E in cancer prevention

31 March 2020

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The role of ascorbic acid in oral cancer and carcinogenesis

31 March 2020

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Serum carotenoids and oxidative DNA damage in human lymphocytes.

31 March 2020

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Ex vivo assessment of lymphocyte antioxidant status using the comet assay

31 March 2020

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A simpler, more robust method for the analysis of 8-oxoguanine in DNA

31 March 2020

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DNA oxidation matters: The HPLC–electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine

31 March 2020

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Smoking and low antioxidant levels increase oxidative damage to sperm DNA.

31 March 2020

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Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes.

31 March 2020

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Childhood cancer and parental use of tobacco: deaths from 1971 to 1976

31 March 2020

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Childhood cancer and parental use of alcohol and tobacco

31 March 2020

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Childhood cancer and parental use of tobacco: deaths from 1953 to 1955.

31 March 2020

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Paternal Cigarette Smoking and the Risk of Childhood Cancer Among Offspring of Nonsmoking Mothers

31 March 2020

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Iron-induced carcinogenesis: the role of redox regulation

31 March 2020

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Iron and colorectal cancer risk: human studies.

31 March 2020

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Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats.

31 March 2020

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The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age.

31 March 2020

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Zinc homeostasis in humans

31 March 2020

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Assessment of marginal zinc status in humans

31 March 2020

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Zinc: health effects and research priorities for the 1990s

31 March 2020

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The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

31 March 2020

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Maternal dietary zinc influences DNA strand break and 8-hydroxy-2'-deoxyguanosine levels in infant rhesus monkey liver

31 March 2020

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Oxidant defense systems in testes from zinc-deficient rats

31 March 2020

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Esophageal carcinogenesis in the rat: zinc deficiency, DNA methylation and alkyltransferase activity.

31 March 2020

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Induction of esophageal tumors in zinc-deficient rats by single low doses of N-nitrosomethylbenzylamine (NMBA): analysis of cell proliferation, and mutations in H-ras and p53 genes

31 March 2020

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Cell proliferation and esophageal carcinogenesis in the zinc-deficient rat

31 March 2020

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Esophageal cancer prevention in zinc-deficient rats: rapid induction of apoptosis by replenishing zinc

31 March 2020

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Protective action of zinc against cobalt-induced testicular damage in the mouse

31 March 2020

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Concentrations of cadmium, lead, selenium, and zinc in human blood and seminal plasma

31 March 2020

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Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial

31 March 2020

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Use of Multivitamin/Mineral Prenatal Supplements: Influence on the Outcome of Pregnancy

31 March 2020

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Clinical practice. What vitamins should I be taking, doctor?

31 March 2020

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Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance

31 March 2020

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Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial

31 March 2020

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Serum 25-hydroxyvitamin D, dietary calcium intake, and distal colorectal adenoma risk

31 March 2020

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Vitamin D receptor activity and prevention of colonic hyperproliferation and oxidative stress.

31 March 2020

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Dairy products, calcium, and prostate cancer risk in the Physicians' Health Study

31 March 2020

2 references

31 March 2020

inferred from DOI database lookup

7 January 2021

based on heuristic

Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer

1 reference

Selected micronutrients and oral and pharyngeal cancer

31 March 2020

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Role of macronutrients, vitamins and minerals in the aetiology of squamous-cell carcinoma of the oesophagus

31 March 2020

1 reference

Insulin: a novel factor in carcinogenesis

31 March 2020

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Epidemiology of breast cancer.

31 March 2020

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Obesity, cancer links prompt new recommendations

31 March 2020

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Role of phytochemicals in prevention and treatment of prostate cancer

31 March 2020

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Dietary intake, dietary patterns, and changes with age: an epidemiological perspective

31 March 2020

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The Metabolic Tune-Up: Metabolic Harmony and Disease Prevention

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRC886

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Dimensions Publication ID

4 August 2017

1048661237

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