The unconventional lifestyle of NKT cells (Q34770393)

4 August 2017

1 reference

title

The unconventional lifestyle of NKT cells (English)

1 reference

regulation of NK T cell differentiation

4 August 2017

main subject

1 reference

negative regulation of NK T cell differentiation

GO:0051136

1 reference

positive regulation of NK T cell proliferation

GO:0051137

1 reference

positive regulation of NK T cell differentiation

GO:0051142

1 reference

1 reference

regulation of NK T cell activation

GO:0051132

1 reference

positive regulation of NK T cell activation

GO:0051133

1 reference

negative regulation of NK T cell proliferation

GO:0051135

1 reference

regulation of NK T cell proliferation

GO:0051141

1 reference

negative regulation of NK T cell activation

GO:0051140

1 reference

Laurent Gapin

1 reference

4 August 2017

Mitchell Kronenberg

1 reference

4 August 2017

publication date

1 August 2002

1 reference

Nature Reviews Immunology

4 August 2017

published in

1 reference

4 August 2017

1 reference

4 August 2017

1 reference

4 August 2017

page(s)

557-568

1 reference

Mouse CD1-specific NK1 T cells: development, specificity, and function

4 August 2017

cites work

1 reference

NKT cells: facts, functions and fallacies.

31 March 2020

1 reference

An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

31 March 2020

1 reference

CD1 recognition by mouse NK1+ T lymphocytes

31 March 2020

1 reference

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

31 March 2020

1 reference

In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers

31 March 2020

1 reference

Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

31 March 2020

1 reference

Murine CD1d-restricted T cell recognition of cellular lipids

31 March 2020

1 reference

TCR beta chain influences but does not solely control autoreactivity of V alpha 14J281T cells

31 March 2020

1 reference

CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution

31 March 2020

1 reference

CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells

31 March 2020

1 reference

CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver

31 March 2020

1 reference

Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells

31 March 2020

1 reference

CD1d-Restricted NKT Cells: An Interstrain Comparison

31 March 2020

1 reference

Lineage relationships and differentiation of natural killer (NK) T cells: intrathymic selection and interleukin (IL)-4 production in the absence of NKR-P1 and Ly49 molecules

31 March 2020

1 reference

NKT cells derive from double-positive thymocytes that are positively selected by CD1d

31 March 2020

1 reference

A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage

31 March 2020

1 reference

A population of CD62Llow Nk1.1- CD4+ T cells that resembles NK1.1+ CD4+ T cells

31 March 2020

1 reference

CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice

31 March 2020

1 reference

The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families

31 March 2020

1 reference

A major fraction of human bone marrow lymphocytes are Th2-like CD1d-reactive T cells that can suppress mixed lymphocyte responses.

31 March 2020

1 reference

Comparative contribution of CD1 on the development of CD4+ and CD8+ T cell compartments

31 March 2020

1 reference

NKT cells are phenotypically and functionally diverse

31 March 2020

1 reference

NK markers are expressed on a high percentage of virus-specific CD8+ and CD4+ T cells

31 March 2020

1 reference

Emergence of CD8+ T cells expressing NK cell receptors in influenza A virus-infected mice

31 March 2020

1 reference

Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2)

31 March 2020

1 reference

Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes

31 March 2020

1 reference

Immune suppression and skin cancer development: regulation by NKT cells.

31 March 2020

1 reference

Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells

31 March 2020

1 reference

Impaired NK1+ T cell development and early IL-4 production in CD1-deficient mice.

31 March 2020

1 reference

CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4

31 March 2020

1 reference

Recognition and function of Valpha14 NKT cells

31 March 2020

1 reference

A subset of CD4+ thymocytes selected by MHC class I molecules

31 March 2020

1 reference

Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice

31 March 2020

1 reference

NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells.

31 March 2020

1 reference

In vitro and in vivo analysis of bone marrow-derived CD3+, CD4-, CD8-, NK1.1+ cell lines

31 March 2020

1 reference

Extrathymic development of V alpha 14-positive T cells

31 March 2020

1 reference

CD1d-glycolipid tetramers: A new tool to monitor natural killer T cells in health and disease

31 March 2020

1 reference

Three day neonatal thymectomy selectively depletes NK1.1+ T cells

31 March 2020

1 reference

Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes

31 March 2020

1 reference

Selective events in T cell development

31 March 2020

1 reference

Positive and negative selection invoke distinct signaling pathways.

31 March 2020

1 reference

The Src family tyrosine kinase Fyn regulates natural killer T cell development

31 March 2020

1 reference

Cutting edge: the Ets1 transcription factor is required for the development of NK T cells in mice

31 March 2020

1 reference

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

31 March 2020

1 reference

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

31 March 2020

1 reference

Requirement for membrane lymphotoxin in natural killer cell development.

31 March 2020

1 reference

Membrane lymphotoxin is required for the development of different subpopulations of NK T cells.

31 March 2020

1 reference

Lack of directed V alpha 14-J alpha 281 rearrangements in NK1+ T cells

31 March 2020

1 reference

Defective development of NK1.1+ T-cell antigen receptor alphabeta+ cells in zeta-associated protein 70 null mice with an accumulation of NK1.1+ CD3- NK-like cells in the thymus

31 March 2020

1 reference

Induction of differentiation of pre-NKT cells to mature Valpha14 NKT cells by granulocyte/macrophage colony-stimulating factor

31 March 2020

1 reference

Natural killer T cells reactive to a single glycolipid exhibit a highly diverse T cell receptor beta repertoire and small clone size

31 March 2020

1 reference

CD4-CD8- thymocytes that express the T cell receptor may have previously expressed CD8.

31 March 2020

1 reference

Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.

31 March 2020

1 reference

Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

31 March 2020

1 reference

Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells

31 March 2020

1 reference

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

31 March 2020

1 reference

Precursors of functional MHC class I- or class II-restricted CD8alphaalpha(+) T cells are positively selected in the thymus by agonist self-peptides

31 March 2020

1 reference

Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d

31 March 2020

1 reference

Developmental and functional analyses of CD8(+) NK1.1(+) T cells in class-I-restricted TCR transgenic mice.

31 March 2020

1 reference

Early onset of CD8 transgene expression inhibits the transition from DN3 to DP thymocytes.

31 March 2020

1 reference

Natural Killer T Cells Restricted by the Monomorphic MHC Class 1b CD1d1 Molecules Behave Like Inflammatory Cells

31 March 2020

1 reference

Comparison of the T cell patterns in leprous and cutaneous sarcoid granulomas. Presence of Valpha24-invariant natural killer T cells in T-cell-reactive leprosy together with a highly biased T cell receptor Valpha repertoire

31 March 2020

1 reference

MIP-2 recruits NKT cells to the spleen during tolerance induction

31 March 2020

1 reference

Monocyte chemoattractant protein-1-dependent increase of V alpha 14 NKT cells in lungs and their roles in Th1 response and host defense in cryptococcal infection.

31 March 2020

1 reference

Neonatal invariant Valpha24+ NKT lymphocytes are activated memory cells.

31 March 2020

1 reference

Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: critical role for B7 in CD1d-dependent NKT cell interferon gamma production

31 March 2020

1 reference

Regulation of NKT cells by Ly49: analysis of primary NKT cells and generation of NKT cell line

31 March 2020

1 reference

CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant V alpha 24 J alpha Q T cell receptor alpha chains

31 March 2020

1 reference

A clonal view of alphabeta T cell responses

31 March 2020

1 reference

Fas/Fas ligand interactions promote activation-induced cell death of NK T lymphocytes

31 March 2020

1 reference

Activation of hepatic NKT cells and subsequent liver injury following administration of α-galactosylceramide

31 March 2020

2 references

31 March 2020

inferred from DOI database lookup

7 January 2021

based on heuristic

Critical contribution of IFN-γ and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of α-galactosylceramide

1 reference

Rapid Death and Regeneration of NKT Cells in Anti-CD3ε- or IL-12-Treated Mice

31 March 2020

1 reference

Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus.

31 March 2020

1 reference

Developmentally regulated extinction of Ly-49 receptor expression permits maturation and selection of NK1.1+ T cells

31 March 2020

1 reference

Differential regulation of Ly49 expression on CD4+ and CD4-CD8- (double negative) NK1.1+ T cells

31 March 2020

1 reference

Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells

31 March 2020

1 reference

The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes

31 March 2020

1 reference

Natural killer T cell ligand alpha-galactosylceramide enhances protective immunity induced by malaria vaccines

31 March 2020

1 reference

Immunization with alpha-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis.

31 March 2020

1 reference

Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

31 March 2020

1 reference

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

31 March 2020

1 reference

Distinct cytokine profiles of neonatal natural killer T cells after expansion with subsets of dendritic cells

31 March 2020

1 reference

Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining

31 March 2020

1 reference

Distinct functional lineages of human V(alpha)24 natural killer T cells

31 March 2020

1 reference

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

31 March 2020

1 reference

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

31 March 2020

1 reference

Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

31 March 2020

1 reference

Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Valpha14 natural killer T cells

31 March 2020

1 reference

CD1d-restricted immunoglobulin G formation to GPI-anchored antigens mediated by NKT cells

31 March 2020

1 reference

Cutting edge: the IgG response to the circumsporozoite protein is MHC class II-dependent and CD1d-independent: exploring the role of GPIs in NK T cell activation and antimalarial responses

31 March 2020

1 reference

CD1d-restricted NK T cells are dispensable for specific antibody responses and protective immunity against liver stage malaria infection in mice.

31 March 2020

1 reference

alpha -galactosylceramide-activated Valpha 14 natural killer T cells mediate protection against murine malaria

31 March 2020

1 reference

Resistance to malarial infection is achieved by the cooperation of NK1.1(+) and NK1.1(-) subsets of intermediate TCR cells which are constituents of innate immunity

31 March 2020

1 reference

Natural killer T cell activation inhibits hepatitis B virus replication in vivo.

31 March 2020

1 reference

Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection

31 March 2020

1 reference

Selective reduction of T cells bearing invariant V alpha 24J alpha Q antigen receptor in patients with systemic sclerosis

31 March 2020

1 reference

Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage

31 March 2020

1 reference

Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy

31 March 2020

1 reference

Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases

31 March 2020

1 reference

Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells

31 March 2020

1 reference

NKT-associated markers and perforin in hyperplastic thymuses from patients with Myasthenia gravis

31 March 2020

1 reference

NKT cells - conductors of tumor immunity?

31 March 2020

1 reference

Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

31 March 2020

1 reference

The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells

31 March 2020

1 reference

Sequential production of interferon-gamma by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of alpha -galactosylceramide

31 March 2020

1 reference

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis

31 March 2020

1 reference

Differential tumor surveillance by natural killer (NK) and NKT cells.

31 March 2020

1 reference

NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway

31 March 2020

1 reference

Association between alphabetaTCR+CD4-CD8- T-cell deficiency and IDDM in NOD/Lt mice

31 March 2020

1 reference

A defect in interleukin 12-induced activation and interferon gamma secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus.

31 March 2020

1 reference

alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

31 March 2020

1 reference

Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice

31 March 2020

1 reference

Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

31 March 2020

1 reference

Multiple immuno-regulatory defects in type-1 diabetes

31 March 2020

1 reference

Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

31 March 2020

1 reference

CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

31 March 2020

1 reference

Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis

31 March 2020

1 reference

CD4(+) v(alpha)14 NKT cells play a crucial role in an early stage of protective immunity against infection with Leishmania major

31 March 2020

1 reference

The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids

31 March 2020

1 reference

Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis

31 March 2020

1 reference

Murine natural killer T(NKT) cells [correction of natural killer cells] contribute to the granulomatous reaction caused by mycobacterial cell walls

31 March 2020

1 reference

Resistance of natural killer T cell-deficient mice to systemic Shwartzman reaction

31 March 2020

1 reference

Potent expansion of human natural killer T cells using alpha-galactosylceramide (KRN7000)-loaded monocyte-derived dendritic cells, cultured in the presence of IL-7 and IL-15

31 March 2020

1 reference

The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells

31 March 2020

1 reference

Generation of NK1.1+ T cell antigen receptor alpha/beta+ thymocytes associated with intact thymic structure

31 March 2020

1 reference

Impaired NK1.1 T cell development in mice transgenic for a T cell receptor beta chain lacking the large, solvent-exposed cbeta FG loop

31 March 2020

1 reference

Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice

31 March 2020

1 reference

Critical contribution of liver natural killer T cells to a murine model of hepatitis

31 March 2020

1 reference

Augmentation of Valpha14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis

31 March 2020

1 reference

NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance

31 March 2020

1 reference

Requirement for natural killer T (NKT) cells in the induction of allograft tolerance

31 March 2020

1 reference

CD4(+) Valpha14 natural killer T cells are essential for acceptance of rat islet xenografts in mice

31 March 2020

1 reference

Involvement of decidual Valpha14 NKT cells in abortion

31 March 2020

1 reference

Cutting edge: CD1d deficiency impairs murine host defense against the spirochete, Borrelia burgdorferi

31 March 2020

1 reference

Activation of Valpha14(+) natural killer T cells by alpha-galactosylceramide results in development of Th1 response and local host resistance in mice infected with Cryptococcus neoformans

31 March 2020

1 reference

Enhanced gamma interferon production through activation of Valpha14(+) natural killer T cells by alpha-galactosylceramide in interleukin-18-deficient mice with systemic cryptococcosis

31 March 2020

1 reference

During Trypanosoma cruzi infection CD1d-restricted NK T cells limit parasitemia and augment the antibody response to a glycophosphoinositol-modified surface protein

31 March 2020

1 reference

A thymic precursor to the NK T cell lineage

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI854

0 references

1 reference