Amphiregulin: role in mammary gland development and breast cancer. (Q34768776)

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English	Amphiregulin: role in mammary gland development and breast cancer.	scientific article

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Europe PubMed Central

PubMed publication ID

18398673

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

review article

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Europe PubMed Central

title

Amphiregulin: role in mammary gland development and breast cancer (English)

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Europe PubMed Central

PubMed publication ID

18398673

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

author

Jean McBryan

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1

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Europe PubMed Central

PubMed publication ID

18398673

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

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5 January 2020

Jillian Howlin

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2

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Europe PubMed Central

PubMed publication ID

18398673

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

author name string

Silvia Napoletano

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3

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Europe PubMed Central

PubMed publication ID

18398673

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

Finian Martin

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4

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Europe PubMed Central

PubMed publication ID

18398673

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

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5 January 2020

publication date

9 April 2008

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Europe PubMed Central

PubMed publication ID

18398673

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

published in

Journal of Mammary Gland Biology and Neoplasia

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Europe PubMed Central

PubMed publication ID

18398673

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

volume

13

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Europe PubMed Central

PubMed publication ID

18398673

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

issue

2

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Europe PubMed Central

PubMed publication ID

18398673

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

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5 January 2020

page(s)

159-169

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Europe PubMed Central

PubMed publication ID

18398673

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

cites work

A heparin sulfate-regulated human keratinocyte autocrine factor is similar or identical to amphiregulin

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1007%2FS10911-008-9075-7

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21 January 2018

The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity

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21 January 2018

Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin is a potent mitogen for the vascular smooth muscle cell line, A7r5.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of mammary stroma in modulating the proliferative response to ovarian hormones in the normal mammary gland

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin in lung branching morphogenesis: interaction with heparan sulfate proteoglycan modulates cell proliferation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERalpha-CITED1 co-regulated genes expressed during pubertal mammary gland development: implications for breast cancer prognosis.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell surface ectodomain cleavage of human amphiregulin precursor is sensitive to a metalloprotease inhibitor. Release of a predominant N-glycosylated 43-kDa soluble form

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of epidermal-growth-factor receptor in tumor progression in transformed human mammary epithelial cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of ductal morphogenesis and lobular hyperplasia by amphiregulin in the mouse mammary gland.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammary gland development in adult mice requires epithelial and stromal estrogen receptor alpha

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel role for amphiregulin in protection from liver injury

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin-EGFR signaling regulates PTHrP gene expression in breast cancer cells.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of the transcriptional changes underlying functional defects in the mammary glands of prolactin receptor knockout mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of the cardiac defect in ErbB2 mutant mice reveals essential roles of ErbB2 in peripheral nervous system development

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene targeting of ErbB3 using a Cre-mediated unidirectional DNA inversion strategy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen regulation of mammary gland development and breast cancer: amphiregulin takes center stage

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and function of the epidermal growth factor receptor and erbB-2 during mammary gland morphogenesis.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-anchored growth factors.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling through the stromal epidermal growth factor receptor is necessary for mammary ductal development.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammary gland development and tumorigenesis in estrogen receptor knockout mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen and phorbol esters regulate amphiregulin expression by two separate mechanisms in human breast cancer cell lines

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preneoplastic mammary tumor markers: Cripto and Amphiregulin are overexpressed in hyperplastic stages of tumor progression in transgenic mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin is a novel growth factor involved in normal bone development and in the cellular response to parathyroid hormone stimulation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparin inhibition of autonomous growth implicates amphiregulin as an autocrine growth factor for normal human mammary epithelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection and location of amphiregulin and Cripto-1 expression in the developing postnatal mouse mammary gland

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CITED1 homozygous null mice display aberrant pubertal mammary ductal morphogenesis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting TACE-dependent EGFR ligand shedding in breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted Expression of a Dominant Negative Epidermal Growth Factor Receptor in the Mammary Gland of Transgenic Mice Inhibits Pubertal Mammary Duct Development

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pubertal mammary gland development: insights from mouse models

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin: an early trigger of liver regeneration in mice.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations of gene expression in the development of early hyperplastic precursors of breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin induces tyrosine phosphorylation of the epidermal growth factor receptor and p185erbB2. Evidence that amphiregulin acts exclusively through the epidermal growth factor receptor at the surface of human epithelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin, epidermal growth factor receptor, and estrogen receptor expression in human primary breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of human amphiregulin: a member of the epidermal growth factor family

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin-dependent proliferation of cultured human keratinocytes: autocrine growth, the effects of exogenous recombinant cytokine, and apparent requirement for heparin-like glycosaminoglycans

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of cell proliferation and protease secretion by epidermal growth factor and amphiregulin in tumoral versus normal breast epithelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor beta-1 and amphiregulin act in synergy to increase the production of urokinase-type plasminogen activator in transformed breast epithelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparan sulfate is essential to amphiregulin-induced mitogenic signaling by the epidermal growth factor receptor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of ErbB2/Neu in the mammary epithelium results in impaired ductal outgrowth

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of a nuclear factor kappaB/interleukin-1 positive feedback loop by amphiregulin in human breast cancer cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elucidation of a role for stromal steroid hormone receptors in mammary gland growth and development using tissue recombinants

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of HSulf-1 expression enhances autocrine signaling mediated by amphiregulin in breast cancer.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin as an autocrine growth factor for c-Ha-ras- and c-erbB-2-transformed human mammary epithelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ErbB2 is required for ductal morphogenesis of the mammary gland

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver regeneration

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent parity-induced changes in growth factors, TGF-beta3, and differentiation in the rodent mammary gland.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of amphiregulin in breast cancer.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response to and expression of amphiregulin by ovarian carcinoma and normal ovarian surface epithelial cells: nuclear localization of endogenous amphiregulin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic expression and activation of ERBB receptors in the developing mouse mammary gland

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisense expression for amphiregulin suppresses tumorigenicity of a transformed human breast epithelial cell line

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18398673

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S10911-008-9075-7

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18398673

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

PubMed publication ID

18398673

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18398673

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18398673%20AND%20SRC:MED&resulttype=core&format=json

retrieved

5 January 2020

ResearchGate publication ID

5453383

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